OBJECTIVES: This study aims to explore the current status and risk factors of oral health-related quality of life OHRQoL in patients with mental disorders and provide evidence for effective intervention measures. METHODS: A total of 397 patients diagnosed with mental illness were selected by convenience sampling, and investigation was carried out using general data questionnaire, health literacy in dentistry-14 (HeLD-14), oral health impact profile-14 (OHIP-14), and oral health status checklist. RESULTS: The total score of OHIP-14 in patients with mental disorders was 8(2, 14). The score of HeLD-14 was negatively correlated with the score of OHIP-14 (r=-0.142, P<0.01). The results of multiple linear regression showed that six variables including annual family income, schizophrenia, sweets, frequency of visits to the dentist, dental caries, and missing teeth affected OHRQoL of patients with mental disorders (P<0.05). CONCLUSIONS The poor OHRQoL of psychiatric patients is associated with many factors. Medical personnel should pay attention to their oral health problems and develop targeted oral care programs throughout the course of disease to improve oral health and related quality of life of patients.
Humans ; Quality of Life ; Oral Health ; Mental Disorders ; Risk Factors ; Surveys and Questionnaires ; Male ; Female ; Dental Caries ; Adult ; Middle Aged ; Schizophrenia

OBJECTIVES: This study aimed to construct a risk prediction model for the occurrence of the demora-lization syndrome in patients with oral cancer and provide a scientific basis for the prevention of this syndrome in patients with oral cancer and the development of personalized care programs. METHODS: A total of 486 patients with oral cancer in West China Hospital of Stomatology of Sichuan University and Sun Yat-sen Memorial Hospital of Sun Yat-sen University from 2024 March to July were selected by convenience sampling. We integrated clinical data and evidence from previous studies to identify the key variables affecting the demoralization syndrome in patients with oral cancer. The 486 patients were divided into a training set and a validation set in an 8∶2 ratio. A clinical risk prediction model was established based on the individual data of 365 patients in the development cohort. Through least absolute shrinkage and selection operator (LASSO) regression, a moderate to severe risk prediction model of demoralization syndrome in oral cancer was constructed, and a clinical machine-learning nomogram was constructed. Bootstrap resampling was used for internal validation. The data of 121 patients in the validation cohort were externally validated. RESULTS: The incidence of the demoralization syndrome in patients with oral cancer was 405 cases (83.3%), of which 279 cases (57.4%) were mild, 176 cases (36.2%) were moderate, and 31 cases (6.4%) were severe. The core model, including patient education level, disease understanding, and MDASI-HN score, was used to predict the risk of outcome. Internal validation of the model yielded C statistic of 0.783 6 (95% CI: 0.78-0.87), beta of 0.843 4, and calibration intercept of -0.040 6. Through external validation, the validation set C statistic was 0.80 (95%CI: 0.71-0.87), beta was 0.80, and calibration intercept was -0.08. CONCLUSIONS Our risk prediction mo-del of the demoralization syndrome in patients with oral cancer performed robustly in validation cohorts of different nur-sing environments. The model has good correction and good discrimination and can be used as an evaluation and prediction item at admission.
Humans ; Mouth Neoplasms/complications* ; Male ; Female ; Nomograms ; Middle Aged ; Syndrome ; Aged ; Adult ; Risk Factors ; Risk Assessment ; Machine Learning

Three soil conditioners were prepared from granulated food waste and decomposed cattle manure combined with desulfurization gypsum, coal gangue, and maifanite, respectively. Field trials were conducted in the saline field growing Cabernet Sauvignon. The effects of soil conditioners on rhizospheric bacterial communities were studied, with the aim of providing a scientific basis for soil amelioration and restoration. Five treatments were designed, including the control (T1), conventional fertilization (T2), reduced chemical fertilization+organic matter-based soil conditioner with calcium additives (T3), reduced chemical fertilization+organic matter-based soil conditioner with silica additives (T4), and reduced chemical fertilization+organic matter-based soil conditioner with magnesium additives (T5), each with three replications. The results indicated that soil conditioners improved the rhizospheric nutrients, yield, and quality of grape (P<0.05), increased relative abundance of Proteobacteria by 17.32%-23.37%, decreased relative abundance of unidentified_Bacteria and Acidobacteriota by 4.22%-28.42% and 20.88%-35.81%, respectively. The bacterial community composition and diversity were different between treatments. Function analysis showed that the expression levels of the genes involved in chromosome and protein synthesis, mRNA biosynthesis, and glyoxylate and dicarboxylate metabolism were up-regulated in the treatments with soil conditioners. The correlation analysis revealed that multiple environmental factors affected the alpha diversity of rhizospheric bacterial communities, and some bacterial taxa were closely related to the grape yield and quality. It is concluded that soil conditioners can effectively alter rhizosphere nutrient levels and bacterial community structures and functions. T5 treatment outperforms other treatments in improving the physico-chemical and biological characteristics of rhizosphere, and the yield, and quality of grape. It has potential for application, and provides an important basis for development of new-type soil conditioners.
Soil Microbiology ; Rhizosphere ; Soil/chemistry* ; Vitis/microbiology* ; Fertilizers ; Bacteria/growth & development* ; Cattle ; Manure ; Animals

Objective This study aimed to investigate the incidence and severity of surgical fear in patients with oral and maxillofacial tumors.Methods The survey participants were composed of patients with oral and maxillofacial tu-mors,who were scheduled to undergo surgery.A general information questionnaire,the Surgical Fear Questionnaire(SFQ),the Patient Health Questionnaire(PHQ)-9,and the Generalized Anxiety Disorder(GAD)-7 score were used for the investigation.Results A total of 203 patients were investigated.Among them,85.22%had fear of surgery.The me-dian score of SFQ was 20,and the quartile was(6,36).The patients were categorized into none,mild,moderate,and severe groups according fear level.Gender,diabetes,obvious discomfort before surgery,PHQ-9,and GAD-7 scores were the variables with statistical difference in each fear level.Multifactor analysis showed that women were more likely to have moderate and severe fear than men(OR=2.19,P=0.03;OR=2.72,P=0.01),patients with obvious preoperative discomfort symptoms were more inclined to have no fear(OR=4.73,P=0.02),and patients with diabetes were more likely to have severe fear(OR=3.33,P=0.02).The incidence rates of depression and anxiety were 31.03%and 24.63%,respectively.The incidence of anxiety and de-pression in patients with severe fear was 40.00%.Surgical fear was moderately positively correlated with anxiety(r=0.491,P<0.001)and depression(r=0.514,P<0.001).Conclusion The fear of surgery in patients with oral and maxillo-facial tumors is common and distributed in all levels.Medical staff can screen and assess patients with moderate and se-vere fear of surgery in accordance with the influencing factors and implement targeted interventions to reduce fear of sur-gery,anxiety,and depression on the basis of the source of fear.

Objective This study aimed to explore the risk factors of postoperative hypokalemia in patients with oral cancer and to provide a basis for preventing and controlling postoperative hypokalemia.Methods We included 366 pa-tients undergoing oral cancer surgery in the Department of Head and Neck Oncology,West China Hospital of Stomatolo-gy,Sichuan University from January 2022 to August 2022.Univariate and multivariate analyses were used to determine the risk factors of postoperative hypokalemia.The receiver operation characteristic(ROC)curve was used to quantify the effectiveness of the factors.A nomogram of the risk factors for postoperative hypokalemia in oral cancer patients was de-veloped and validated.Results A total of 224 patients(61.20％)had postoperative hypokalemia,the lowest serum po-tassium level(3.50±0.35)mmol/L on the 4th day after surgery,and the highest incidence of hypokalemia(54.68％).Vari-ables with P＜0.05 in the univariate analysis were quantified by ROC curve followed by multivariate logistic regression analysis.Results showed an independent correlation with postoperative hypokalemia as follows:preoperative se-rum potassium＜3.87 mmol/L(P=0.008),preoperative se-rum calcium＜2.31 mmol/L(P=0.033),preoperative PNI＜49.16(P=0.032),postoperative drainage volume＞264.25 mL(P=0.002).The above variables were constructed into a postoperative hypokalemia risk nomogram and verified,and a good degree of fit was found.Conclusion The indepen-dent risk factors for postoperative hypokalemia in patients with oral cancer were as follows:preoperative serum potassi-um＜3.87 mmol/L,preoperative serum calcium＜2.31 mmol/L,preoperative PNI＜49.16,and postoperative drainage vol-ume＞264.25 mL.Clinical attention should be paid to managing the above high-risk patients.Preventive potassium sup-plementation should be performed as soon as possible to reduce hypokalemia occurrence.

Objective To investigate the related influencing factors of unplanned reoperation (UR) in patients with oral cancer.Methods A total of 160 oral cancer patients with UR who were hospitalized in the Department of Head and Neck Oncology,West China Hospital of Stomatology,Sichuan University from Janu-ary 1,2018 to December 31,2022 were selected as the study group,and another 160 patients without UR in the same period were selected as the matching group by 1:1 matching.The clinical data of the two groups were compared.The variables that met the requirements were screened.The multivariate logistic stepwise regres-sion model was further used to analyze the influencing factors of UR in oral cancer.Results UR mostly oc-curred within one day after surgery in patients with oral cancer (66.88％),mainly due to flap vascular crisis (48.13％).Compared with the matched group,the hospitalization time of the study group was prolonged,the hospitalization cost was increased,and the differences were statistically significant (P<0.05).Multivariate lo-gistic stepwise regression analysis showed that albumin and neutrophil-lymphocyte-ratio score (ANS,OR=1.693,95％CI:1.207-2.347,P=0.002),difference in hemoglobin levels before and after surgery (OR=1.056,95％CI:1.035-1.077,P<0.001) and free tissue flap repair (OR=4.609,95％CI:2.350-9.036,P<0.001) were the influencing factors for UR in patients with oral cancer.Conclusion UR prolongs the hospi-talization time and increases the hospitalization cost of patients.High ANS,large difference in hemoglobin lev-els before and after surgery,and free tissue flap repair are independent risk factors for UR in patients with oral cancer.

Objective:To explore the clinical training needs for postgraduates with master's degree in oral nursing based on job competency, so as to provide a basis for improving the postgraduate training system and enhancing the job competency of postgraduates with master's degree in oral nursing.Methods:This study was descriptive and qualitative. From March to April 2023, purposive sampling was used to select 8 postgraduates with master's degree in oral nursing for semi-structured in-depth interviews. The targeted content analysis method was used for data sorting and analysis.Results:The clinical training needs for postgraduates with master's degree in oral nursing based on job competency were summarized into four themes and 13 sub-themes, namely self-awareness (understanding of oral nursing, understanding of postgraduates with master's degree in oral nursing, understanding of the current training model for postgraduates with master's degree in oral nursing), ability traits (self-learning ability, reform and innovation ability, interpersonal communication ability), learning motivation (self-improvement, career development, serving society), and clinical training needs (theoretical knowledge, skill operation, scientific research and innovation ability, evidence-based practice ability) .Conclusions:Universities should collaborate with hospitals to develop clinical training plans and carry out theoretical and practical education for postgraduates with master's degree in oral nursing, and pay attention to the cultivation of the research innovation and evidence-based practice abilities of postgraduates with master's degree in oral nursing, in order to help them further improve their job competency.

Objective:To analyze the current status, development trends, and gaps in studies on symptom clusters in patients with head and neck tumors using bibliometric methods.Methods:Relevant literature on symptom clusters in patients with head and neck tumors was retrieved from databases including China National Knowledge Infrastructure, WanFang data, China Biology Medicine disc, Web of Science Core Collection, PubMed, and Scopus. A visual analysis of the literature content was conducted.Results:A total of 37 studies were included. The studies primarily focused on patients with nasopharyngeal carcinoma. Symptom clusters in patients with head and neck tumors demonstrated dynamic variability. Emerging trends in this field include nutrition-related symptom clusters, symptom interventions, and the identification of core symptoms. However, current studies still exhibit limitations, such as using singular research tools and clustering methods and a lack of exploration of internal mechanisms.Conclusions:Future research should focus on improving study design through multidisciplinary collaboration, utilizing data mining techniques to systematically explore the internal mechanisms of symptom clusters in patients with head and neck tumors, identifying symptom intervention targets, and conducting high-quality intervention studies to verify the reliability and effectiveness of these targets and interventions.

Objective:To explore the research status, hotspots and trends in the field of discharge readiness in the past 20 years.Methods:We searched the article on discharge readiness in the core collection of Web of Science published from January 1, 2000 to March 23, 2022. Visual analysis was implemented through CiteSpace software.Results:A total of 3 781 articles were included. The country with the largest number of publications was the United States. The author with the largest number of publications was Professor Mor of Brown University. The journal with the largest number of publications and the largest influence of literature was the Journal of Clinical Nursing. The research hotspot keywords on discharge readiness were care, outcome, mortality, frailty, skilled nursing facility, and hospital readmission. The research hotspots were nursing and geriatrics. The people concerned were the elderly and newborn. The diseases concerned were chronic diseases and surgeries. The research frontier was to reduce the incidence of postoperative complications and readmission rate of elderly patients through out-of-hospital continuous nursing services based on multidisciplinary team cooperation. Conclusions:Researchers should carry out the research of hospital-community-family out-of-hospital continuous nursing service led by nurses for elderly patients with chronic diseases based on the multidisciplinary team cooperation.

Objective:To form the expert consensus on screening and evaluation of dysphagia with oral cancer patients (abbreviated as Consensus) , so as to standardize the relevant contents of screening and evaluation of dysphagia in the whole cycle of oral cancer. Methods:By referring to domestic and foreign literature related to dysphagia, combining with the specialty characteristics of oral cancer and the clinical experience of experts, a preliminary consensus was formed through in-depth interviews with experts. A total of 21 experts were selected for three rounds of expert letter consultation and expert meeting, the corresponding items were sorted out, analyzed and modified based on expert opinions, and the Consensus was finally formed. Results:The effective recovery rates of the three rounds of correspondence were 100.00% (21/21) , the expert authority coefficient was 0.91, the variation coefficient of each item was 0.04-0.20, and Kendall's harmony coefficient was 0.05 ( P<0.05) . The final consensus included four aspects, such as the effect of oral cancer on swallowing, the clinical manifestations of dysphagia, the basic procedures of screening and evaluation and the prevention and treatment of complications during evaluation. Conclusions:This Consensus is scientific and practical, which can provide clinical guidance for the screening and evaluation of dysphagia in the whole cycle of oral cancer.