1.Oral health-related quality of life status and risk factors in patients with mental disorders.
Xuemei YANG ; Hongyu WANG ; Yonghua TANG ; Chengjun YIN ; Jingya YU ; Xiaoqin BI
West China Journal of Stomatology 2025;43(1):84-91
OBJECTIVES:
This study aims to explore the current status and risk factors of oral health-related quality of life OHRQoL in patients with mental disorders and provide evidence for effective intervention measures.
METHODS:
A total of 397 patients diagnosed with mental illness were selected by convenience sampling, and investigation was carried out using general data questionnaire, health literacy in dentistry-14 (HeLD-14), oral health impact profile-14 (OHIP-14), and oral health status checklist.
RESULTS:
The total score of OHIP-14 in patients with mental disorders was 8(2, 14). The score of HeLD-14 was negatively correlated with the score of OHIP-14 (r=-0.142, P<0.01). The results of multiple linear regression showed that six variables including annual family income, schizophrenia, sweets, frequency of visits to the dentist, dental caries, and missing teeth affected OHRQoL of patients with mental disorders (P<0.05).
CONCLUSIONS
The poor OHRQoL of psychiatric patients is associated with many factors. Medical personnel should pay attention to their oral health problems and develop targeted oral care programs throughout the course of disease to improve oral health and related quality of life of patients.
Humans
;
Quality of Life
;
Oral Health
;
Mental Disorders
;
Risk Factors
;
Surveys and Questionnaires
;
Male
;
Female
;
Dental Caries
;
Adult
;
Middle Aged
;
Schizophrenia
2.Risk prediction of demoralization syndrome in patients with oral cancer.
Liyan MAO ; Xixi YANG ; Xiaoqin BI ; Min LIU ; Chongyang ZHAO ; Zuozhen WEN
West China Journal of Stomatology 2025;43(3):395-405
OBJECTIVES:
This study aimed to construct a risk prediction model for the occurrence of the demora-lization syndrome in patients with oral cancer and provide a scientific basis for the prevention of this syndrome in patients with oral cancer and the development of personalized care programs.
METHODS:
A total of 486 patients with oral cancer in West China Hospital of Stomatology of Sichuan University and Sun Yat-sen Memorial Hospital of Sun Yat-sen University from 2024 March to July were selected by convenience sampling. We integrated clinical data and evidence from previous studies to identify the key variables affecting the demoralization syndrome in patients with oral cancer. The 486 patients were divided into a training set and a validation set in an 8∶2 ratio. A clinical risk prediction model was established based on the individual data of 365 patients in the development cohort. Through least absolute shrinkage and selection operator (LASSO) regression, a moderate to severe risk prediction model of demoralization syndrome in oral cancer was constructed, and a clinical machine-learning nomogram was constructed. Bootstrap resampling was used for internal validation. The data of 121 patients in the validation cohort were externally validated.
RESULTS:
The incidence of the demoralization syndrome in patients with oral cancer was 405 cases (83.3%), of which 279 cases (57.4%) were mild, 176 cases (36.2%) were moderate, and 31 cases (6.4%) were severe. The core model, including patient education level, disease understanding, and MDASI-HN score, was used to predict the risk of outcome. Internal validation of the model yielded C statistic of 0.783 6 (95% CI: 0.78-0.87), beta of 0.843 4, and calibration intercept of -0.040 6. Through external validation, the validation set C statistic was 0.80 (95%CI: 0.71-0.87), beta was 0.80, and calibration intercept was -0.08.
CONCLUSIONS
Our risk prediction mo-del of the demoralization syndrome in patients with oral cancer performed robustly in validation cohorts of different nur-sing environments. The model has good correction and good discrimination and can be used as an evaluation and prediction item at admission.
Humans
;
Mouth Neoplasms/complications*
;
Male
;
Female
;
Nomograms
;
Middle Aged
;
Syndrome
;
Aged
;
Adult
;
Risk Factors
;
Risk Assessment
;
Machine Learning
3.Soil conditioners affect rhizospheric bacterial communities of Cabernet Sauvignon.
Shuaicheng AN ; Jiangtao BI ; Gong LI ; Ruifan MAO ; Peng LIU ; Zhibing HUI ; Xiaoqin SU
Chinese Journal of Biotechnology 2025;41(6):2432-2450
Three soil conditioners were prepared from granulated food waste and decomposed cattle manure combined with desulfurization gypsum, coal gangue, and maifanite, respectively. Field trials were conducted in the saline field growing Cabernet Sauvignon. The effects of soil conditioners on rhizospheric bacterial communities were studied, with the aim of providing a scientific basis for soil amelioration and restoration. Five treatments were designed, including the control (T1), conventional fertilization (T2), reduced chemical fertilization+organic matter-based soil conditioner with calcium additives (T3), reduced chemical fertilization+organic matter-based soil conditioner with silica additives (T4), and reduced chemical fertilization+organic matter-based soil conditioner with magnesium additives (T5), each with three replications. The results indicated that soil conditioners improved the rhizospheric nutrients, yield, and quality of grape (P<0.05), increased relative abundance of Proteobacteria by 17.32%-23.37%, decreased relative abundance of unidentified_Bacteria and Acidobacteriota by 4.22%-28.42% and 20.88%-35.81%, respectively. The bacterial community composition and diversity were different between treatments. Function analysis showed that the expression levels of the genes involved in chromosome and protein synthesis, mRNA biosynthesis, and glyoxylate and dicarboxylate metabolism were up-regulated in the treatments with soil conditioners. The correlation analysis revealed that multiple environmental factors affected the alpha diversity of rhizospheric bacterial communities, and some bacterial taxa were closely related to the grape yield and quality. It is concluded that soil conditioners can effectively alter rhizosphere nutrient levels and bacterial community structures and functions. T5 treatment outperforms other treatments in improving the physico-chemical and biological characteristics of rhizosphere, and the yield, and quality of grape. It has potential for application, and provides an important basis for development of new-type soil conditioners.
Soil Microbiology
;
Rhizosphere
;
Soil/chemistry*
;
Vitis/microbiology*
;
Fertilizers
;
Bacteria/growth & development*
;
Cattle
;
Manure
;
Animals
4.Elevated preoperative troponin T in geriatric hip fracture patients: its value in predicting adverse cardiac events
Yue BI ; Bo GAO ; Xiaoqin WEN ; Jie WANG
Clinical Medicine of China 2025;41(6):401-406
Objective:To investigate the value of elevated preoperative troponin T (TnT) in predicting perioperative adverse cardiac events in geriatric hip fracture patients.Methods:A total of 273 elderly patients undergoing surgical treatment for hip fracture at Department of Cardiology, Tianjin Hospital between January 2024 and December 2024 were enrolled. Basic demographic information was recorded, and preoperative TnT levels were measured. Patients with elevated preoperative TnT ( n=114) were enrolled into the elevated group, while those with normal TnT ( n=159) were enrolled into the normal group. Fracture types included femoral neck fracture ( n=141) and intertrochanteric fracture ( n=132). The impact of elevated preoperative TnT on perioperative major adverse cardiovascular events (MACEs), as well as the influence of different fracture types on MACEs, were analyzed. Normally distributed continuous data were expressed as Mean±SD and compared by independent samples t-test. Categorical data were expressed as case(%) and compared by χ2 test. Multivariate binary logistic regression analysis was performed. The predictive value of TnT for MACEs was assessed by plotting the receiver operating characteristic (ROC) curve and calculating the area under the curve (AUC). Results:The incidence of perioperative MACEs was significantly higher in the elevated TnT group (21.9%, 25/114) compared to the normal TnT group (3.1%, 5/159), with a statistically significant difference ( χ2=23.95, P<0.001). The comparison of postoperative MACEs incidence between different fracture types showed no statistically significant difference [12.1% (17/141) vs. 9.8% (13/132)] ( χ2=0.34, P=0.560). Multivariate binary logistic regression analysis indicated that elevated TnT level ( OR=8.633, 95% CI: 3.117-23.911, P<0.001) was an independent risk factor for perioperative major adverse cardiovascular events (MACEs), increasing the risk by 7.633 times compared to patients with normal TnT. A TnT threshold of ≥0.028 μg/L predicted MACEs with a sensitivity of 0.600 and specificity of 0.954 (AUC=0.839, 95% CI: 0.751-0.926, P<0.05). Conclusion:Troponin T can serve as an independent predictor of perioperative adverse cardiovascular events in elderly patients undergoing surgery for hip fracture and plays a crucial role in the perioperative cardiovascular risk assessment of these patients.
5.Development of a clinical practice training system for postgraduate graduates of the oral nursing profession
Lixia KUANG ; Yu ZHANG ; Lu BAI ; Guangma WANG ; Jingyan YU ; Xuemei YANG ; Liyan MAO ; Xiaoqin BI
Chinese Journal of Practical Nursing 2025;41(23):1765-1772
Objective:To construct a clinical practice training system for master′s degree students specializing in oral nursing based on the competency iceberg model for job performance, and to provide a valuable reference for the clinical training of master′s students in oral nursing.Methods:The research team initially formulated the components of the clinical practice training system through an extensive literature review and semi-structured interviews. From October 17, 2023, to November 13, 2023, the Delphi expert consultation methodology was utilized to facilitate two rounds of inquiries involving 20 specialists in the domain of oral care.Results:The positive coefficients of the two rounds of expert inquiries were 95.24% (20/21) and 100.00% (21/21). The authority coefficients were 0.925 and 0.929, while the variation coefficients ranged from 0.00 to 0.22 and from 0.05 to 0.11. Additionally, Kendall′s harmony coefficients were 0.229 and 0.319 (both P<0.01). The finalized training system included training objectives, training content, training requirements and examinations, totaling 3 first-level items, 18 second-level items and 67 third-level items. Conclusions:The training system of clinical practice for oral nursing graduate students constructed in this study is informative and reliable, and can provide reference for clinical practice of professional postgraduates in oral nursing.
6.Health care needs of oral cancer patients at different stages of the disease: a qualitative study
Chinese Journal of Modern Nursing 2025;31(11):1494-1499
Objective:To explore the health care needs of oral cancer patients at different stages of the disease based on timing theory to provide a reference for developing health care programs for oral cancer patients.Methods:Purposive sampling was used to select patients who were hospitalized in the Department of Head and Neck Tumor Surgery of West China Hospital of Stomatology, Sichuan University, from January to April 2023, as respondents. Timing theory was used as the theoretical framework to develop the interview outline, information was collected through semi-structured interviews, and content analysis was used to analyze the data.Results:By synthesizing the health care needs of oral cancer patients with surgery at five stages of 48 hours after admission, three days after surgery, seven days after surgery, two weeks after discharge, and onemonth after discharge, seven themes and 19 sub-themes were extracted, including support for disease-related information (condition and treatment modalities, surgical costs, and reimbursement by medical insurance), alleviation of adverse emotions (surgical anxiety, hopelessness in diagnosis and treatment, fear of recurrence, and loss of self-worth), symptom management needs (management of oral-related symptom clusters, individualized symptom management), guidance on health care skills (postoperative family care skills, oral wound care, diet and nutritional care), and functional rehabilitation training (oral function training, motor function training), follow-up treatment guidance (consultation for abnormalities, arrangements for follow-up consultation, guidance on preparation for radiotherapy, and other treatment recommendations), and self-management needs (healthy life management, coping strategies) .Conclusions:Oral cancer patients with surgery have multiple healthcare needs in the first month after surgery. It is recommended that healthcare professionals conduct a comprehensive assessment of the patient's relevant needs and provide staged symptom management and personalized health guidance to the patient.
7.Development of a clinical practice training system for postgraduate graduates of the oral nursing profession
Lixia KUANG ; Yu ZHANG ; Lu BAI ; Guangma WANG ; Jingyan YU ; Xuemei YANG ; Liyan MAO ; Xiaoqin BI
Chinese Journal of Practical Nursing 2025;41(23):1765-1772
Objective:To construct a clinical practice training system for master′s degree students specializing in oral nursing based on the competency iceberg model for job performance, and to provide a valuable reference for the clinical training of master′s students in oral nursing.Methods:The research team initially formulated the components of the clinical practice training system through an extensive literature review and semi-structured interviews. From October 17, 2023, to November 13, 2023, the Delphi expert consultation methodology was utilized to facilitate two rounds of inquiries involving 20 specialists in the domain of oral care.Results:The positive coefficients of the two rounds of expert inquiries were 95.24% (20/21) and 100.00% (21/21). The authority coefficients were 0.925 and 0.929, while the variation coefficients ranged from 0.00 to 0.22 and from 0.05 to 0.11. Additionally, Kendall′s harmony coefficients were 0.229 and 0.319 (both P<0.01). The finalized training system included training objectives, training content, training requirements and examinations, totaling 3 first-level items, 18 second-level items and 67 third-level items. Conclusions:The training system of clinical practice for oral nursing graduate students constructed in this study is informative and reliable, and can provide reference for clinical practice of professional postgraduates in oral nursing.
8.Elevated preoperative troponin T in geriatric hip fracture patients: its value in predicting adverse cardiac events
Yue BI ; Bo GAO ; Xiaoqin WEN ; Jie WANG
Clinical Medicine of China 2025;41(6):401-406
Objective:To investigate the value of elevated preoperative troponin T (TnT) in predicting perioperative adverse cardiac events in geriatric hip fracture patients.Methods:A total of 273 elderly patients undergoing surgical treatment for hip fracture at Department of Cardiology, Tianjin Hospital between January 2024 and December 2024 were enrolled. Basic demographic information was recorded, and preoperative TnT levels were measured. Patients with elevated preoperative TnT ( n=114) were enrolled into the elevated group, while those with normal TnT ( n=159) were enrolled into the normal group. Fracture types included femoral neck fracture ( n=141) and intertrochanteric fracture ( n=132). The impact of elevated preoperative TnT on perioperative major adverse cardiovascular events (MACEs), as well as the influence of different fracture types on MACEs, were analyzed. Normally distributed continuous data were expressed as Mean±SD and compared by independent samples t-test. Categorical data were expressed as case(%) and compared by χ2 test. Multivariate binary logistic regression analysis was performed. The predictive value of TnT for MACEs was assessed by plotting the receiver operating characteristic (ROC) curve and calculating the area under the curve (AUC). Results:The incidence of perioperative MACEs was significantly higher in the elevated TnT group (21.9%, 25/114) compared to the normal TnT group (3.1%, 5/159), with a statistically significant difference ( χ2=23.95, P<0.001). The comparison of postoperative MACEs incidence between different fracture types showed no statistically significant difference [12.1% (17/141) vs. 9.8% (13/132)] ( χ2=0.34, P=0.560). Multivariate binary logistic regression analysis indicated that elevated TnT level ( OR=8.633, 95% CI: 3.117-23.911, P<0.001) was an independent risk factor for perioperative major adverse cardiovascular events (MACEs), increasing the risk by 7.633 times compared to patients with normal TnT. A TnT threshold of ≥0.028 μg/L predicted MACEs with a sensitivity of 0.600 and specificity of 0.954 (AUC=0.839, 95% CI: 0.751-0.926, P<0.05). Conclusion:Troponin T can serve as an independent predictor of perioperative adverse cardiovascular events in elderly patients undergoing surgery for hip fracture and plays a crucial role in the perioperative cardiovascular risk assessment of these patients.
9.Health care needs of oral cancer patients at different stages of the disease: a qualitative study
Chinese Journal of Modern Nursing 2025;31(11):1494-1499
Objective:To explore the health care needs of oral cancer patients at different stages of the disease based on timing theory to provide a reference for developing health care programs for oral cancer patients.Methods:Purposive sampling was used to select patients who were hospitalized in the Department of Head and Neck Tumor Surgery of West China Hospital of Stomatology, Sichuan University, from January to April 2023, as respondents. Timing theory was used as the theoretical framework to develop the interview outline, information was collected through semi-structured interviews, and content analysis was used to analyze the data.Results:By synthesizing the health care needs of oral cancer patients with surgery at five stages of 48 hours after admission, three days after surgery, seven days after surgery, two weeks after discharge, and onemonth after discharge, seven themes and 19 sub-themes were extracted, including support for disease-related information (condition and treatment modalities, surgical costs, and reimbursement by medical insurance), alleviation of adverse emotions (surgical anxiety, hopelessness in diagnosis and treatment, fear of recurrence, and loss of self-worth), symptom management needs (management of oral-related symptom clusters, individualized symptom management), guidance on health care skills (postoperative family care skills, oral wound care, diet and nutritional care), and functional rehabilitation training (oral function training, motor function training), follow-up treatment guidance (consultation for abnormalities, arrangements for follow-up consultation, guidance on preparation for radiotherapy, and other treatment recommendations), and self-management needs (healthy life management, coping strategies) .Conclusions:Oral cancer patients with surgery have multiple healthcare needs in the first month after surgery. It is recommended that healthcare professionals conduct a comprehensive assessment of the patient's relevant needs and provide staged symptom management and personalized health guidance to the patient.
10.Current status and influencing factors of fear of surgery in patients with oral and maxillofacial tumors
Yu ZHANG ; Lixia KUANG ; Xiaoqin BI ; Xueli ZHAN ; Tianyu ZHANG
West China Journal of Stomatology 2024;42(4):494-501
Objective This study aimed to investigate the incidence and severity of surgical fear in patients with oral and maxillofacial tumors.Methods The survey participants were composed of patients with oral and maxillofacial tu-mors,who were scheduled to undergo surgery.A general information questionnaire,the Surgical Fear Questionnaire(SFQ),the Patient Health Questionnaire(PHQ)-9,and the Generalized Anxiety Disorder(GAD)-7 score were used for the investigation.Results A total of 203 patients were investigated.Among them,85.22%had fear of surgery.The me-dian score of SFQ was 20,and the quartile was(6,36).The patients were categorized into none,mild,moderate,and severe groups according fear level.Gender,diabetes,obvious discomfort before surgery,PHQ-9,and GAD-7 scores were the variables with statistical difference in each fear level.Multifactor analysis showed that women were more likely to have moderate and severe fear than men(OR=2.19,P=0.03;OR=2.72,P=0.01),patients with obvious preoperative discomfort symptoms were more inclined to have no fear(OR=4.73,P=0.02),and patients with diabetes were more likely to have severe fear(OR=3.33,P=0.02).The incidence rates of depression and anxiety were 31.03%and 24.63%,respectively.The incidence of anxiety and de-pression in patients with severe fear was 40.00%.Surgical fear was moderately positively correlated with anxiety(r=0.491,P<0.001)and depression(r=0.514,P<0.001).Conclusion The fear of surgery in patients with oral and maxillo-facial tumors is common and distributed in all levels.Medical staff can screen and assess patients with moderate and se-vere fear of surgery in accordance with the influencing factors and implement targeted interventions to reduce fear of sur-gery,anxiety,and depression on the basis of the source of fear.

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