1.Study on the effect of Bian-stone-based herbal heat therapy on gastrointestinal reactions during the precon-ditioning period of hematopoietic stem cell transplantation patients
Binlian YAO ; Min XU ; Xiaopei MAO ; Min PENG ; Rui ZHU ; Xiaolan ZHANG ; Menghua YE ; Danhua YANG
Chinese Journal of Nursing 2025;60(12):1420-1426
Objective Exploring the effect of Bian-stone-based herbal heat therapy on herbal heat ironing in gastrointestinal reactions during the preconditioning period of hematopoietic stem cell transplantation patients.Methods Convenience sampling method was used to select 68 cases of hematopoietic stem cell transplantation patients who attended the hematology department of a tertiary-level Chinese medicine hospital in Hangzhou from October 2023 to April 2024 as the study subjects,and the SPSS 26.0 statistical software was used to generate a random number for grouping into an experimental and a control group,with 34 cases in each group.On the basis of intravenous antiemetic medication and routine,the experimental group implemented the Bian-stone-based herbal heat therapy on the basis of intravenous antiemetic medication and conventional nursing care.In the control group,intravenous antiemetic drugs and routine care were used,and the intervention duration of both groups was 14 d,of which 7 d was a course of treatment,with a total of 2 courses of treatment.The incidence of gastroin-testinal reactions,Gastrointestinal Symptom Rating Scale(GSRS)score,Pepsin Ⅰ(PG Ⅰ),Pepsin Ⅱ(PG Ⅱ),and the ratio of PG Ⅰ to PG Ⅱ(PGR)before and after the intervention were compared between the 2 groups.Results The final sample of 66 cases was collected in this study,and 1 patient was dislodged from each of the control group and the experimental group.The comparison of the incidence of gastrointestinal reactions between the 2 groups within 14 days showed that the incidences of nausea,vomiting,abdominal distension,and diarrhea were lower in the experimental group than those in the control group(P<0.05).GSRS scores on days 1,8,and 14 of intervention were compared,and there were effects between groups in both groups(F=5.338,P=0.017).The levels of PG Ⅰ,PG Ⅱ in the experimental group on day 8 of the intervention were lower than those in the control group.The levels of PGR was higher than that in the control group(all P<0.05).The safety of the 2 groups after treatment was evaluated,and the results showed that no serious adverse events occurred in the 2 groups.Conclusion Bian-stone-based herbal heat therapy can improve gastrointestinal reactions and reduce the incidence of gastrointestinal reactions during the preconditioning period of hematopoietic stem cell transplantation patients,which provides clinical guidance for the application of Bian-stone-based herbal heat therapy by nursing staff in the future.
2.Study on the effect of Bian-stone-based herbal heat therapy on gastrointestinal reactions during the precon-ditioning period of hematopoietic stem cell transplantation patients
Binlian YAO ; Min XU ; Xiaopei MAO ; Min PENG ; Rui ZHU ; Xiaolan ZHANG ; Menghua YE ; Danhua YANG
Chinese Journal of Nursing 2025;60(12):1420-1426
Objective Exploring the effect of Bian-stone-based herbal heat therapy on herbal heat ironing in gastrointestinal reactions during the preconditioning period of hematopoietic stem cell transplantation patients.Methods Convenience sampling method was used to select 68 cases of hematopoietic stem cell transplantation patients who attended the hematology department of a tertiary-level Chinese medicine hospital in Hangzhou from October 2023 to April 2024 as the study subjects,and the SPSS 26.0 statistical software was used to generate a random number for grouping into an experimental and a control group,with 34 cases in each group.On the basis of intravenous antiemetic medication and routine,the experimental group implemented the Bian-stone-based herbal heat therapy on the basis of intravenous antiemetic medication and conventional nursing care.In the control group,intravenous antiemetic drugs and routine care were used,and the intervention duration of both groups was 14 d,of which 7 d was a course of treatment,with a total of 2 courses of treatment.The incidence of gastroin-testinal reactions,Gastrointestinal Symptom Rating Scale(GSRS)score,Pepsin Ⅰ(PG Ⅰ),Pepsin Ⅱ(PG Ⅱ),and the ratio of PG Ⅰ to PG Ⅱ(PGR)before and after the intervention were compared between the 2 groups.Results The final sample of 66 cases was collected in this study,and 1 patient was dislodged from each of the control group and the experimental group.The comparison of the incidence of gastrointestinal reactions between the 2 groups within 14 days showed that the incidences of nausea,vomiting,abdominal distension,and diarrhea were lower in the experimental group than those in the control group(P<0.05).GSRS scores on days 1,8,and 14 of intervention were compared,and there were effects between groups in both groups(F=5.338,P=0.017).The levels of PG Ⅰ,PG Ⅱ in the experimental group on day 8 of the intervention were lower than those in the control group.The levels of PGR was higher than that in the control group(all P<0.05).The safety of the 2 groups after treatment was evaluated,and the results showed that no serious adverse events occurred in the 2 groups.Conclusion Bian-stone-based herbal heat therapy can improve gastrointestinal reactions and reduce the incidence of gastrointestinal reactions during the preconditioning period of hematopoietic stem cell transplantation patients,which provides clinical guidance for the application of Bian-stone-based herbal heat therapy by nursing staff in the future.
3.Summary of best evidence for diarrhea assessment and management in hematopoietic stem cell transplantation patients
Xiaopei MAO ; Min XU ; Xiaolan ZHANG ; Min PENG ; Fang CHENG ; Wangfang SHEN ; Menghua YE
Chinese Journal of Modern Nursing 2024;30(30):4163-4170
Objective:To retrieve, evaluate, and summarize evidence on the assessment and management of diarrhea in hematopoietic stem cell transplantation (HSCT) patients both domestically and internationally, providing evidence-based support for clinical practice.Methods:According to the "6S" model, guidelines, clinical decisions, recommended practices, evidence summaries, systematic reviews, and expert consensus related to the assessment and management of diarrhea in HSCT patients were systematically retrieved from relevant databases and websites both domestically and internationally. The search period was from January 1, 2013 to November 30, 2023. Seven researchers conducted literature screening, quality evaluation, evidence extraction, and summarization.Results:A total of 15 articles were included, including four guidelines, three clinical decisions, two recommended practices, one evidence summary, two systematic reviews, and three expert consensus. Thirty-one pieces of evidence were summarized from seven aspects of multidisciplinary management, risk factor management, assessment and monitoring, medication intervention, diet and nutrition management, health education, and daily management.Conclusions:The best evidence for HSCT patient assessment and management summarized can provide reference for clinical practice, and nursing staff should carefully apply evidence based on the actual situation of patients.
4.Application of scenario simulation teaching combined with modular training in nursing education of medical rescue in manned space flight
Xiaopei GAO ; Peiming SUN ; Jing LI ; Liping DING ; Lianyong LI ; Junfeng GAO ; Xiaoming LIU ; Shuai MAO ; Yuxia CHENG
Chinese Journal of Emergency Medicine 2023;32(5):632-636
Objective:To study the application of scenario simulation teaching combined with modular training in nursing education of medical rescue in manned space flight.Methods:Twenty nurses from the medical rescue team of Strategic Support Force Characteristic Medical Center were selected as the research objects. The research objects were randomly divided into the scenario simulation combined with practical training group (practical training group, n=10) and traditional teaching group (control group, n=10). Scenario simulation teaching combined with modular training and traditional teaching were used to carry out nursing training. After the training, theoretical assessment, operation assessment and satisfaction survey were organized. Results:The scenario simulation teaching combined with modular training group was significantly better than the traditional training group in theory assessment, operation assessment and satisfaction survey of nursing staff (all P<0.05). Conclusions:Scenario simulation teaching combined with modular training has obvious teaching effect, which can improve the ability and quality of nursing staff, and help to complete the manned space medical rescue mission efficiently.
5.The characteristics and coping strategies of medical support mission in rescue and landing of Shenzhou-14 manned spacecraft
Peiming SUN ; Tao WANG ; Shuai MAO ; Xiaopei GAO ; Xiaoming LIU ; Junfeng GAO ; Jianwu YANG ; Heming YANG ; Ke LI
Chinese Journal of Emergency Medicine 2023;32(7):903-907
Objective:To review the characteristics and coping strategies of the rescue and landing medical support mission of Shenzhou-14 manned spacecraft.Methods:The characteristics of rescue and landing medical support mission of Shenzhou-14 manned spacecraft was analyzed, and the coping strategies and experience were discussed.Results:(1) The characteristics of rescue and landing medical support mission of Shenzhou-14 manned spacecraft included: long time in space station and high-intensity space missions; high-density space medical support mission in short term; special environmental factors in severe cold night; complex terrain of landing site; and the young medical support team. (2) The main coping strategies of rescue and landing medical support mission of Shenzhou-14 manned spacecraft included: strengthened the organization and leadership and improved the training model; reinforcement learning the medical treatment plan and strengthened the medical rescue skills training; optimized the carrying equipment and added the heat preservation and lighting measures; improved the medical rescue process and perfected the emergency plan; emphasized on the scientific research as important as mission; and strengthened the physical exercise and cold resistance exercise.Conclusions:The characteristics and coping strategies of rescue and landing medical support mission of Shenzhou-14 manned spacecraft are summarized to provide the experience for space medical rescue and offer the support for China's manned space industry.
6.Effect of Rehabilition Nursing with Early Movement Getting Out of Bed to Exercise on Patients after Total Hip Replacement (47 Case Report)
Zhifang ZHAO ; Yuwen YANG ; Xiaopei MAO ; Yi HONG ; Xiuyan LI ; Yufeng GE
Chinese Journal of Rehabilitation Theory and Practice 2008;14(6):597-598
Objective To evaluate the effect of rehabilitation nursing with movement getting out of bed in early period after operation on the patients undergone the total hip replacement (THR).Methods The rehabilitation nursing was performed to 47 patients undergone THR including movement getting out of bed in early period; prepared sufficiently pre-operatively (evaluation and rehabilitation training); avoided the complications post-operatively; monitored the vital signs; trained standardizely; relieved pain sufficiently; took off the tubing as early as possible; rehabilitated with the walking aid.Results None had DVT, dislocation, fracture around the prosthesis, infections, death etc, all patients got out of bed in the 1st day after operation, the average time in hospital was 19 days, and the average Harris scores were 54.26, 62.55, 73.58, 91.17 and 93.35 at pre-operation, and in 14th day, 1st month, 3rd month and 6th month post-operation respectively.Conclusion Rehabilitation nursing with early movement getting out of bed to exercise after THR operation can promote the recovery of the hip function, reduce the complications, shorten the hospital stay.
7.Reoperation for local recurrence after resection of rectal carcinoma(a report of 25 cases)
Chinese Journal of General Surgery 2001;10(3):237-240
Objective To explore the factors related to local recurrence after resection of rectal carcinoma and the significance of reoperation. Methods A retrospective analysis was made on the clinical date of 25 cases who had local recurrence after resection of rectal carcinoma. Results The primary operation revealed that 19 cases were in Dukes stage B,15 in stage C.8 cases were low-differentiated adenocarcinoma,2 adenocarcinoma and 3 malignant chang of villous adenoma. The distal incision margin from the tunor was <3 cm in 16 cases, >3cm in 9. Radical operation was performed in 12 cases, palliative opration in 9; and non-resection procedure was made in 4. The median survival time in radical operation group was 30 months, in palliative opration group 12 months, and in non-resection group 2.3 months. 5-year survival rate in reopration patients was 21.7%. Conclusions Local recurrence after resection of rectal carcinoma is closely related to the Duckes' classification, histological type of tumor, and selection of operation.Active surgical intervention is indicated for local recurrence after resection of rectal carcinoma which can prolong the patient's survival time.


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