Polycystic ovary syndrome (PCOS) is a common gynecological disease, and its pathogenesis is closely related to the intestinal microbiota. This article summarizes the multi-target and multi-pathway of Traditional Chinese Medicine intervention in the treatment of PCOS with intestinal microbiota, in order to provide new ideas for clinical diagnosis and treatment from four aspects: chronic inflammation, oxidative stress, hyperandrogenism and abnormal glucose and lipid metabolism.

Polycystic ovary syndrome (PCOS) is a common gynecological disease, and its pathogenesis is closely related to the intestinal microbiota. This article summarizes the multi-target and multi-pathway of Traditional Chinese Medicine intervention in the treatment of PCOS with intestinal microbiota, in order to provide new ideas for clinical diagnosis and treatment from four aspects: chronic inflammation, oxidative stress, hyperandrogenism and abnormal glucose and lipid metabolism.

Polycystic ovary syndrome (PCOS) is a common gynecological endocrine disease, mostly associated with menstrual disorders, obesity, anovulation, etc., and 50%-70% with insulin resistance (IR), its pathogenesis is still unclear. Gut microbiota is a microecosystem involved in the occurrence and development of diseases as an environmental factor. A number of studies have shown that gut microbiota is closely related to the occurrence of PCOS. This paper summarizes the correlation between gut microbiota and IR-PCOS, and summarizes the mechanism of gut microbiota in IR-PCOS through low-grade inflammation, oxidative stress, DNA methylation and glucolipid metabolism, so as to provide new ideas for clinical diagnosis and treatment.

Polycystic ovary syndrome (PCOS) is a common gynecological endocrine disease, mostly associated with menstrual disorders, obesity, anovulation, etc., and 50%-70% with insulin resistance (IR), its pathogenesis is still unclear. Gut microbiota is a microecosystem involved in the occurrence and development of diseases as an environmental factor. A number of studies have shown that gut microbiota is closely related to the occurrence of PCOS. This paper summarizes the correlation between gut microbiota and IR-PCOS, and summarizes the mechanism of gut microbiota in IR-PCOS through low-grade inflammation, oxidative stress, DNA methylation and glucolipid metabolism, so as to provide new ideas for clinical diagnosis and treatment.