1.Effect of position angle on gastric insufflation during induction of general anesthesia in pediatric patients undergoing day surgery
Niqiao CHEN ; Xiaoqiang SUN ; Xiaoling NONG ; Zhijie LIANG ; Jiamei LIANG ; Yixing LU ; Shunzhong JING ; Anyuan LIU ; Yunan LIN
Chongqing Medicine 2025;54(10):2246-2251
Objective To investigate the effect of body position angle on gastric insufflation during the induction of general anesthesia in pediatric patients undergoing day surgery.Methods A total of 111 children scheduled for elective tracheal intubation under general anesthesia at the First Affiliated Hospital of Guangxi Medical University from December 2022 to March 2023 were selected as study subjects.Six children were ex-cluded due to unclear sonographic visualization of the gastric antrum,resulting in 105 children ultimately in-cluded in the study.The children were divided into three groups using a random number table method:Group D0(supine position),Group D5(5° head-up position),and Group D10(10° head-up position),with 35 children in each group.The presence of a"comet-tail artifact"on ultrasound was used as the criterion for determining gastric insufflation during anesthesia induction.The gastric antrum cross-sectional area(CSA)of the gastric antrum was measured before mask ventilation after loss of consciousness(T1)and immediately after tracheal intubation following mask ventilation(T2).The incidence of gastric insufflation,changes in CSA and their differences,and vital sign changes at T1 and T2,were compared among the three groups.Results Compared with Group D0,the incidence of gastric insufflation was significantly lower in Groups D5 and D10[25.7%(9/35)vs.20.0%(7/35)vs.54.0%(19/35)],and the difference was statistically significant(P<0.05).Howev-er,there was no significant difference between Group D5 and Group D10(P>0.05).No significant difference was observed in CSA at T1 among the three groups(P>0.05).At T2,a statistically significant difference in CSA was found among the three groups(P<0.05),with Group D10 showing a smaller CSA than Group D0(P<0.05).The difference in CSA changes was statistically significant among the three groups(P<0.05),with Groups D5 and D10 exhibiting smaller changes than Group D0,and Group D10 showing a smaller change than Group D5(P<0.05).No significant differences were observed in mean artery pressure(MAP),heart rate,pulse oxygen saturation(SpO2)and pressure of end-tidal carbon dioxide(PETCO2)at T1 and T2 among the three groups(P>0.05).A total of 6 children(5.7%)required brief adjustments in jaw support due to irregular PETCO2 waveforms or abnormal peak airway pressure.Conclusion In pediatric patients undergoing day sur-gery under general anesthesia,a 5° head-up position during induction significantly reduces the incidence of gas-tric insufflation and minimizes changes in gastric antral CSA,while a 10° head-up position does not provide ad-ditional benefits.
2.Functional and prognostic assessment of children with severe disorders of consciousness using convalescent somatosensory evoked potentials
Ying FENG ; Xiaoling DUAN ; Li LIN ; Liang TAO ; Mingqiang ZHANG ; Qiuyi HUANG ; Nong XIAO
Chinese Journal of Physical Medicine and Rehabilitation 2023;45(11):986-991
Objective:To explore the value of convalescent somatosensory evoked potentials (SEPs) in formulating a prognosis for children with severe disorders of consciousness (DOC) caused by brain trauma, infection or hypoxia.Methods:This was a retrospective cohort study of 286 children with DOC children treated between 2013 and 2021. They were divided into a trauma group ( n=103), an intracranial infection group ( n=101), a hypoxia group ( n=42) and an other-causes group ( n=40). Their consciousness status and functional recovery were obtained in follow-up appointments, and their functional condition 1 year after discharge was assessed using the modified Glasgow Outcome scale (GOS). Results:During 8-year follow-up, 16 had died, with 4 deaths within 1 year. Among the 191 cases followed up to 1 year, children with a bilateral N20 SEP had significantly better functional outcomes than those with unilateral or bilateral N20 absence. For the trauma group, the presence of a bilateral N20 signal was a strong indicator of good functional outcome at the 1-year follow-up, with a specificity of 90.9%, sensitivity of 55.6%, positive predictive value (PPV) of 92.6%, negative predictive value (NPV) of 50% and a positive likelihood rate (PLR) of 6.111. However, for the intracranial infection group, the presence of N20 had a low specificity for predicting good outcomes, though the absence of an N20 potential predicted poor functional outcome at 1 year with a specificity of 82.4%, sensitivity of 62.1%, PPV of 75%, and PLR of 3.517. For the hypoxic group, bilateral N20 could not predict a good prognosis, though its absence meant a poor outcome, with a specificity of 87.5%, sensitivity of 63.6%, PPV of 93.3%, and PLR of 5.818.Conclusion:SEPs during the recovery period can help to formulate a prognosis for children with severe DOC. Traumatic brain injury and the presence of bilateral N20 potentials can be used as a good prognostic indicator. For intracranial infection and hypoxic-ischemic brain injury, the absence of an N20 potential indicates a poor prognosis.
3.The impact on the life quality of children with cerebral palsy of rehabilitation based on the International Classification of Function, Disability and Health for Children and Youth
Maoqun RAN ; Xiaoling DUAN ; Nong XIAO
Chinese Journal of Physical Medicine and Rehabilitation 2018;40(8):594-598
Objective To assess the impact of rehabilitation procedures based on the International Classification of Function,Disability and Health for Children and Youth (ICF-CY) on the life quality of children with cerebral palsy.Methods Sixty children with cerebra] palsy were randomly divided into an observation group and a control group,each of 30.The observation group received an assessment of their physical functioning,physical structure,activity participation and environmental factors,as well as family guidance based on the ICF-CY framework.The control group was evaluated and treated according to traditional methods.The experiment lasted two months.Before the treatment,as well as after one and two months,both groups were evaluated using Barthel index (BI) and the parents' satisfaction was assessed.The two groups' family training was also evaluated after two months of treatment.Results The average BI and parent satisfaction scores of the two groups were not significantly different before the intervention.After one and two months,improvement was observed on both measures in both groups,but the observation groups' ratings were higher at both time points.After the 2 months of treatment there was no significant difference between the two groups in terms of physical functioning,but the average scores on family rehabilitation,activity participation and environment factors were all significantly better for the observation group.Conclusion Treatment based on the ICF-CY framework can more effectively improve the participation of children with cerebral palsy,which should have a positive effect on their life quality.
4.Correlation between oral Helicobacter pylori infection and oral lichen planus:a systematic review
Yangyang SHE ; Yizhou LIANG ; Xiaoling NONG
International Journal of Laboratory Medicine 2017;38(24):3365-3367,3370
Objective This study was performed to explore the association between oral Helicobacter pylori(HP)infection and oral lichen planus(OLP).Methods Some online electronic databases such as PubMed,Embase,Cochrane Library,CNKI,Wanfang and Chongqing VIP were searched for the eligible case control studies.The association between oral HP infection and OLP was esti-mated by the pooled odds ratios(OR)and 95% confidence intervals(95% CI).Statistical analyses were performed by using STA-TA11.0 software.Fixed or random effects model was used to calculate ORs and 95% CI according to heterogeneity.Results A total of 7 studies with 307 patients and 207 healthy controls were included in the current study.The results of meta-analysis showed the patients with OLP had a significantly higher prevalence of oral HP infection compared with the healthy population(OR=8.43, 95% CI:2.90-24.52,P<0.001).Conclusion This study suggested that HP may be a risk factor for OLP.These findings may guide new strategies for OLP therapy and prevention.However,due to the influence of the quality of the included literature,addi-tional high quality of studies with larger sample sizes are needed.

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