1.Effects of an improved perioperative diet management based on enhanced recovery after surgery in patients undergoing total hip arthroplasty
Pu XUE ; Huiping XU ; Yaya ZHAI ; Caijuan GUO ; Xiaojuan LI
Chinese Journal of Modern Nursing 2023;29(20):2734-2737
Objective:To explore the effects of an improved perioperative diet management based on the concept of enhanced recovery after surgery (ERAS) in patients undergoing total hip arthroplasty (THA) .Methods:From May 2020 to May 2022, convenience sampling was used to select 320 patients who underwent their first unilateral THA at the First Affiliated Hospital of Zhengzhou University. According to the random number table method, patients were divided into control group ( n=160) and observation group ( n=160). The control group adopted a routine perioperative diet management, while the observation group improved the perioperative diet management based on the ERAS concept, and nurses performed preoperative fasting and postoperative diet and drinking water nursing according to the plan. We compared the preoperative hunger and thirst between two groups of patients, and recorded the gastrointestinal function such as postoperative anal exhaust and defecation time, bowel sound recovery time, postoperative nausea and vomiting degree, and post eating nausea and vomiting degree between the two groups. Results:The number of preoperative hunger and thirst patients in the observation group was less than that in the control group, and the postoperative exhaust time, defecation time, and bowel sound recovery time were shorter than those in the control group ( P<0.05). The degree of nausea and vomiting after eating after surgery was lower than that in the control group. The differences were all statistically significant ( P<0.05) . Conclusions:The improved perioperative diet management based on ERAS has good clinical effects in THA patients, reducing perioperative discomfort and promoting postoperative gastrointestinal function recovery.
2.Clinical observation on the therapeutic effect of Integration of Traditional Chinese and Western Medicine in the treatment of irritable bowel syndrome of diarrhea type of liver depression and spleen deficiency and its influence on inflammatory factors and intestinal mucosal barrier function
Chinese Journal of Primary Medicine and Pharmacy 2020;27(13):1550-1554
Objective:To explore the therapeutic effect of Integration of Traditional Chinese and Western Medicine in the treatment of irritable bowel syndrome of diarrhea type of liver depression and spleen deficiency, and its influence on inflammatory factors and intestinal mucosal barrier function.Methods:From May 2017 to May 2019, 86 patients with diarrhea-predominant irritable bowel syndrome admitted to the Traditional Chinese Medicine Hospital of Wenling were randomly divided into observation group (43 cases) and control group (43 cases) according to random number table method.The patients in the control group were given trimetastatin tablets, while the patients in the observation group were given traditional Chinese medicine decoction on the basis of the control group.The two groups were treated for 6 weeks.The therapeutic effects, main symptom scores, inflammatory factors, intestinal mucosal barrier function and adverse reactions were compared between the two groups before and after treatment.Results:The total effective rate of the observation group was 93.02%(40/43), which was higher than 67.44%(29/43) of the control group(χ 2=8.871, P<0.05). The main symptom scores of the observation group were (0.52±0.16)points, (0.46±0.12)points, (0.58±0.15)points, (0.39±0.09)points and (0.41±0.10)points, repectively, which were lower than those of the control group[(1.28±0.25)points, (1.16±0.26)points, (1.34±0.27)points, (0.95±0.14)points and (0.93±0.17)points]( t=16.790, 16.030, 16.135, 22.064, 17.289, all P<0.05). The serum levels of IL-6[(8.27±1.38)μg/L] and IL-8[(2.63±0.43)μg/L] in the observation group were lower than those in the control group[(14.39±2.37)μg/L and (4.37±0.56)μg/L]( t=14.633, 16.160, all P<0.05). The levels of plasma endotoxin[(2.68±0.46)U/mL] and D-lactate[(4.87±0.79)μg/L] in the observation group were lower than those in the control group[(3.97±0.63)U/mL and (7.39±0.95)μg/L]( t=10.844, 13.374, all P<0.05). No serious adverse reactions occurred in both two groups. Conclusion:The combination of traditional Chinese and western medicine has good clinical effect in treating diarrhea-predominant irritable bowel syndrome, which can alleviate inflammation and improve intestinal mucosal barrier function, with fewer adverse reactions.
3.Clinical study on the treatment of functional dyspepsia of liver-stomach disharmony with integrated traditional Chinese and western medicine
Chinese Journal of Primary Medicine and Pharmacy 2020;27(16):1938-1942
Objective:To explore the clinical effect of integrated traditional Chinese and western medicine in the treatment of functional dyspepsia of liver-stomach disharmony.Methods:From June 2018 to June 2019, 92 patients with functional dyspepsia admitted to Wenling Hospital of Traditional Chinese Medicine were divided into observation group(46 cases) and control group(46 cases) according to random number table method.The control group was treated with trimebutine maleate orally, while the observation group was treated with self-made traditional Chinese medicine decoction on the basis of the control group.Both two groups were treated for 4 weeks.The therapeutic effect, the changes of TCM symptom score, gastric motility index and adverse reactions were compared between the two groups before and after treatment.Results:The total effective rate of the observation group(93.48%) was higher than that of the control group(69.57%)(χ 2=8.731, P<0.05). After treatment, the scores of upper abdominal pain, abdominal distension and early saturated belch acid in the two groups were lower compared with those before treatment(all P<0.05). After treatment, the scores of upper abdominal pain, abdominal distension and early saturated belch acid in the observation group were lower than those in the control group( t=11.068, 22.320, 15.073, 14.369, all P<0.05). After treatment, the levels of serum MLT and LEP in the two groups were higher than those before treatment(all P<0.05), while the level of CRH were lower than those before treatment(all P<0.05). After treatment, the levels of serum MLT and LEP in the observation group were higher than those in the control group, while the level of CRH in the observation group was lower than that in the control group, the differences between the two groups were statistically significant( t=12.022, 15.884, 16.536, all P<0.05). The incidence of adverse reactions in the observation group(4.35%) was lower than that in the control group(23.91%)(χ 2=7.256, P<0.05). Conclusion:The combination of traditional Chinese and western medicine has good effect on functional dyspepsia of liver-stomach disharmony, it can improve gastric motility, and has few adverse reactions, which is worthy of clinical reference.
4.Clinical Observation on High Colonic Lavement for Delaying Renal Failure in 98 Cases
Journal of Traditional Chinese Medicine 1992;0(11):-
Objective: To observe effect of combination of TCM-WM with high colonic lavement for delaying renal failure. Methods: 98 cases of renal failure at compensatory phase were randomly divided into a treatment group treated with high colonic lavement, twice each week. 2 hours each time, and a control group treated with oral administration of coated aldehyde oxystarch,10g each time, thrice each day, 3 months constituting one course. Results: After lavenment. symptoms were improved, deceaseing velosity of the clearance rate of endogenous creatinine in blood and urine slowed lowered, renal survival rate of kidney increased, and the interval of dialasis and other replacement therapy obviously postponed in the treatment group as compared with that before treatment and the control group. Conclusion: The high colonic lavement has obvious therapeutiv effect in delaying renal failure velosity with a smaller stimulation to the stomach and smal intestine. It is an effective way for conservation treatment of renal failure.

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