Objective To evaluate the value of color Doppler echocardiography and electrocardiography in assessing cardiac function and disease severity in patients with hypertensive heart disease.Methods A retrospective analysis was conducted on 205 patients with hypertensive heart disease who were categorized into 3 groups based on the New York Heart Association(NYHA)criteria:class Ⅱ(n=62),class Ⅲ(n=89)and class Ⅳ(n=54).The demographic characteristics(including gender and age)and the results of color Doppler echocardiography and electrocardiography were extracted from the hospital's medical record system for analyzing the relationships of the diagnostic findings from color Doppler echocardiography and electrocardiography with cardiac function and disease severity.Results Electrocardiography revealed statistically significant intergroup differences in QTc interval,QRS voltage,and QRS duration across 3 groups(P<0.05).Among 3 groups,class Ⅳ group exhibited the most pronounced abnormalities with prolonged QTc interval and QRS duration,along with reduced QRS voltage(P<0.05).Compared with class Ⅱ group,class Ⅲ group had longer QTc interval and QRS duration,alongside lower QRS voltage(P<0.05).Color Doppler echocardiography showed that left ventricular systolic diameter,left ventricular diastolic diameter,left atrial diameter,left ventricular posterior wall thickness,interventricular septum thickness,left ventricular ejection fraction,and E/A ratio differed significantly across 3 groups(P<0.05).Class Ⅳ group exhibited the largest left ventricular systolic diameter,left ventricular diastolic diameter and left atrial diameter,the thickest left ventricular posterior wall and interventricular septum,and the lowest left ventricular ejection fraction and E/A ratio(P<0.05).Compared with class Ⅱ group,class Ⅲ group had enlarged left ventricular systolic diameter,left ventricular diastolic diameter and left atrial diameter,thicker left ventricular posterior wall and interventricular septum,and reduced left ventricular ejection fraction and E/A ratio(P<0.05).Spearman correlation analysis found that QTc interval,QRS duration,left ventricular systolic diameter,left ventricular diastolic diameter,left atrial diameter,left ventricular posterior wall thickness,and interventricular septum thickness were positively correlated with cardiac functional impairments in patients with hypertensive heart disease,while QRS voltage,left ventricular ejection fraction,and E/A ratio were negatively correlated with cardiac functional impairments in patients with hypertensive heart disease(P<0.05).Multiple linear regression analysis identified QTc interval,QRS duration,left ventricular end-systolic diameter,left ventricular end-diastolic diameter,left atrial diameter,left ventricular posterior wall thickness,ventricular septum thickness,QRS voltage,left ventricular ejection fraction,and E/A ratio as critical factors for assessment of cardiac function(P<0.05).Conclusion Color Doppler echocardiography and electrocardiography demonstrate significant clinical utility in evaluating cardiac function and disease severity in patients with hypertensive heart disease.

Objective To evaluate the value of color Doppler echocardiography and electrocardiography in assessing cardiac function and disease severity in patients with hypertensive heart disease.Methods A retrospective analysis was conducted on 205 patients with hypertensive heart disease who were categorized into 3 groups based on the New York Heart Association(NYHA)criteria:class Ⅱ(n=62),class Ⅲ(n=89)and class Ⅳ(n=54).The demographic characteristics(including gender and age)and the results of color Doppler echocardiography and electrocardiography were extracted from the hospital's medical record system for analyzing the relationships of the diagnostic findings from color Doppler echocardiography and electrocardiography with cardiac function and disease severity.Results Electrocardiography revealed statistically significant intergroup differences in QTc interval,QRS voltage,and QRS duration across 3 groups(P<0.05).Among 3 groups,class Ⅳ group exhibited the most pronounced abnormalities with prolonged QTc interval and QRS duration,along with reduced QRS voltage(P<0.05).Compared with class Ⅱ group,class Ⅲ group had longer QTc interval and QRS duration,alongside lower QRS voltage(P<0.05).Color Doppler echocardiography showed that left ventricular systolic diameter,left ventricular diastolic diameter,left atrial diameter,left ventricular posterior wall thickness,interventricular septum thickness,left ventricular ejection fraction,and E/A ratio differed significantly across 3 groups(P<0.05).Class Ⅳ group exhibited the largest left ventricular systolic diameter,left ventricular diastolic diameter and left atrial diameter,the thickest left ventricular posterior wall and interventricular septum,and the lowest left ventricular ejection fraction and E/A ratio(P<0.05).Compared with class Ⅱ group,class Ⅲ group had enlarged left ventricular systolic diameter,left ventricular diastolic diameter and left atrial diameter,thicker left ventricular posterior wall and interventricular septum,and reduced left ventricular ejection fraction and E/A ratio(P<0.05).Spearman correlation analysis found that QTc interval,QRS duration,left ventricular systolic diameter,left ventricular diastolic diameter,left atrial diameter,left ventricular posterior wall thickness,and interventricular septum thickness were positively correlated with cardiac functional impairments in patients with hypertensive heart disease,while QRS voltage,left ventricular ejection fraction,and E/A ratio were negatively correlated with cardiac functional impairments in patients with hypertensive heart disease(P<0.05).Multiple linear regression analysis identified QTc interval,QRS duration,left ventricular end-systolic diameter,left ventricular end-diastolic diameter,left atrial diameter,left ventricular posterior wall thickness,ventricular septum thickness,QRS voltage,left ventricular ejection fraction,and E/A ratio as critical factors for assessment of cardiac function(P<0.05).Conclusion Color Doppler echocardiography and electrocardiography demonstrate significant clinical utility in evaluating cardiac function and disease severity in patients with hypertensive heart disease.

Microwave thermotherapy(MWTT),as a treatment for tumors,lacks specificity and requires sensitizers.Most reported microwave sensitizers are single metal-organic frameworks(MOFs),which must be loaded with ionic liquids to enhance the performance in MWTT.Meanwhile,MWTT is rarely combined with other treatment modalities.Here,we synthesized a novel Fe-Cu bimetallic organic framework FeCuMOF(FCM)by applying a hydrothermal method and further modified it with methyl polyethylene glycol(mPEG).The obtained FCM@PEG(FCMP)showed remarkable heating performance under low-power microwave irradiation;it also acted as a novel nanospheres enzyme to catalyze H2O2 decompo-sition,producing abundant reactive oxygen species(ROS)to deplete glutathione(GSH)and prevent ROS clearance from tumor cells during chemodynamic treatment.The FCMP was biodegradable and demonstrated excellent biocompatibility,allowing it to be readily metabolized without causing toxic effects.Finally,it was shown to act as a suitable agent for T2 magnetic resonance imaging(MRI)in vitro and in vivo.This new bimetallic nanostructure could successfully realize two tumor treatment modalities(MWTTand chemodynamic therapy)and dual imaging modes(T2 MRI and microwave thermal imaging).Our findings represent a breakthrough for integrating the diagnosis and treatment of tumors and pro-vides a reference for developing new microwave sensitizers.

Objective To observe the effects of Shuangliao Houfeng Powder on complications of dental extraction .Methods 280 patients who need dental extraction were recruited into a treatment group and a control group. The treatment group was applied with Shuangliao Houfeng Powder externally on alveolus dentalis after dental extraction, while the control group received no post-treatment after dental extraction. Wound healing and incidence of complications were observed after three days. Results Wound healing in stage 1 showed better results in the treatment group than the control group (P<0.05). Postoperative bleeding time of the treatment group was significantly shorter than the control group (P<0.01) . Besides the treatment group got better improvements in such symptoms as gingival swelling, pain, and difficulty in mouth opening than the control group (P< 0.05). Conclusion Shuangliao Houfeng Powder is effective on complications of dental extraction and worthy of promotion in clinic.

Objective To study the effect of Jiaweiyunvjian on periodontitis in the old.Methods A total of 180 periodontitis patients were randomly recruited into a treatment group and a control group,90 patients in each.The control group was treated with calculus removal and oral metronidazole,while the treatment group was treated with Jiaweiyunvjian on the basis ofthe control group.After both groups were treated for 7 days,therapeutic effects were observed.Results The total effective rate was 90.4%and 73.3%in the treatment group in the control group respectively.There was significant diffefence (P<0.01).In the 6-month follow-up,there were 7 cases(7.4%)relapsed in the treatment group and 16 cases(18.6%)relapsed in the control group,also showing significant difference(P<0.05).Conclusion Jiaweiyunvjian has curative effects on periodontitis of the old people.

OBJECTIVE: To investigate the effect of balloon kyphoplasty combined with bone cement on the treatment osteoporotic vertebral fracture.METHODS: A total of 58 aged patients with single osteoporotic vertebral compression fracture (58 vertebral bodies) were treated with balloon kyphoplasty. The fracture always occurred at T_8-L_4 segment of vertebral body in particular at T_(10)-L_2 segment of thoracic waist. By local anesthesia, lateral or bilateral pedicle of vertebral arch was punctured to injection bone cement under C-arm fluoroscopy.RESULTS: Bone cement leakage occurred in 8 cases, including leakage along posterior longitudinal ligament into adjacent posterior margin of vertebral body (n=1), external edge of vertebral body (n=6), and subcutaneous tissue (n=1); however, all the patients did not have clinical symptoms. C-arm fluoroscopy showed that height of vertebral body was increased, and rachiokyphosis was improved after treatment. Pain was obviously improved, and the easement rate of pain was 100%. There was significant difference in visual simulation score, angle degree of rachiokyphosis, and living activity scale before and 6 months after treatment (P < 0.05), but there was no significant difference between 6 months after treatment and following up stopping (P>0.05).CONCLUSION: Balloon kyphoplasty can significantly ease pain caused by osteoporotic spinal fractures and tumor metastatic spinal fractures and can partially restore vertebral body height and kyphosis deformity, there is conducive to improving spinal function and improving the quality of life.