1.Comparative study on simultaneous bilateral and unilateral posterior vocal cord resection using CO 2 laser for bilateral vocal cord paralysis
Jieying PENG ; Hongliang ZHENG ; Shicai CHEN ; Meng LI ; Wei WANG ; Hao JIANG ; Xiangqiang DUAN ; Caiyun ZHANG ; Yingna GAO ; Mengjie CHEN ; Minhui ZHU
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2025;60(3):338-344
Objective:To compare and analyze the efficacy of bilateral and unilateral posterior vocal cord resection with CO 2 laser under endoscopy in the treatment of bilateral vocal cord paralysis. Methods:This case series study retrospectively analyzed the data of 110 patients with bilateral vocal cord paralysis who underwent endoscopic CO 2 laser posterior cordotomy at the Department of Otolaryngology-Head and Neck Surgery, the First Affiliated Hospital of Naval Medical University, from October 2016 to January 2023. The cohort consisted of 36 males [mean age (45.5±9.1) years, range 24-72 years] and 74 females [mean age (47.2±10.1) years, range 22-67 years]. Among them, 47 patients underwent simultaneous bilateral posterior cordotomy (bilateral cordotomy group), while 63 patients underwent unilateral posterior cordotomy (unilateral cordotomy group). Pre-and postoperative indicators, including swallowing function, glottal size, and vocal function (subjective and objective assessments), were compared between the two surgical approaches. The Wilcoxon signed-rank test was used to analyze changes in swallowing function, glottal size, and vocal function (subjective and objective assessments) within each group before and after surgery, whereas the Mann-Whitney U test was utilized to assess differences between groups. Results:Postoperative follow-up was 1-5 years [median follow-up time was 1.6 (1.3, 2.0) years].The one-time extubation rate was 71.4%(45/63)in the unilateral posterior vocal cord resection group and 87.2%(41/47)in the bilateral posterior vocal cord resection group, significantly higher in the bilateral group ( χ2=3.94, P<0.05). One week after surgery, the swallowing function score of unilateral cordotomy group was 2 (1, 2.5) points, which was significantly better than that of bilateral cordotomy group [2 (1.5, 3) points, Z=-2.118, P<0.05], and the swallowing function score of both groups returned to normal 3 months after surgery. There were no significant differences in preoperative glottic closure during inhalation, auditory perceptual evaluation (GRBAS), objective voice analysis, and Voice Handicap Index-10 (VHI-10) between the two groups ( P>0.05). Postoperatively, the maximum transverse diameter of the posterior glottis during inspiration in the unilateral cordotomy group was 4.49 (4.24, 4.77) mm, significantly smaller than that in the bilateral cordotomy group, which was 5.05 (4.52, 5.62) mm ( Z=-4.103, P<0.05). Among the GRBAS parameters, G (grade of hoarseness), B (breathiness), and A (asthenia), as well as VHI-10 scores and objective voice analysis parameters [jitter, shimmer, harmonic-noise ratio (HNR), and maximum phonation time (MPT)], were significantly better in the unilateral cordotomy group compared to the bilateral cordotomy group, with statistically significant differences ( P<0.05). Conclusions:Unilateral posterior vocal cord resection using CO 2 laser is simple and feasible for the treatment of bilateral vocal cord paralysis, with shorter recovery time, maximal preservation of laryngeal phonatory function, and fewer complications compared to bilateral resection. However, the one-time extubation rate is higher with bilateral resection, reducing the need for a second surgery and associated patient discomfort. This study offers guidance for clinical decision-making in the surgical management of bilateral vocal cord paralysis.
2.Comparative study on simultaneous bilateral and unilateral posterior vocal cord resection using CO 2 laser for bilateral vocal cord paralysis
Jieying PENG ; Hongliang ZHENG ; Shicai CHEN ; Meng LI ; Wei WANG ; Hao JIANG ; Xiangqiang DUAN ; Caiyun ZHANG ; Yingna GAO ; Mengjie CHEN ; Minhui ZHU
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2025;60(3):338-344
Objective:To compare and analyze the efficacy of bilateral and unilateral posterior vocal cord resection with CO 2 laser under endoscopy in the treatment of bilateral vocal cord paralysis. Methods:This case series study retrospectively analyzed the data of 110 patients with bilateral vocal cord paralysis who underwent endoscopic CO 2 laser posterior cordotomy at the Department of Otolaryngology-Head and Neck Surgery, the First Affiliated Hospital of Naval Medical University, from October 2016 to January 2023. The cohort consisted of 36 males [mean age (45.5±9.1) years, range 24-72 years] and 74 females [mean age (47.2±10.1) years, range 22-67 years]. Among them, 47 patients underwent simultaneous bilateral posterior cordotomy (bilateral cordotomy group), while 63 patients underwent unilateral posterior cordotomy (unilateral cordotomy group). Pre-and postoperative indicators, including swallowing function, glottal size, and vocal function (subjective and objective assessments), were compared between the two surgical approaches. The Wilcoxon signed-rank test was used to analyze changes in swallowing function, glottal size, and vocal function (subjective and objective assessments) within each group before and after surgery, whereas the Mann-Whitney U test was utilized to assess differences between groups. Results:Postoperative follow-up was 1-5 years [median follow-up time was 1.6 (1.3, 2.0) years].The one-time extubation rate was 71.4%(45/63)in the unilateral posterior vocal cord resection group and 87.2%(41/47)in the bilateral posterior vocal cord resection group, significantly higher in the bilateral group ( χ2=3.94, P<0.05). One week after surgery, the swallowing function score of unilateral cordotomy group was 2 (1, 2.5) points, which was significantly better than that of bilateral cordotomy group [2 (1.5, 3) points, Z=-2.118, P<0.05], and the swallowing function score of both groups returned to normal 3 months after surgery. There were no significant differences in preoperative glottic closure during inhalation, auditory perceptual evaluation (GRBAS), objective voice analysis, and Voice Handicap Index-10 (VHI-10) between the two groups ( P>0.05). Postoperatively, the maximum transverse diameter of the posterior glottis during inspiration in the unilateral cordotomy group was 4.49 (4.24, 4.77) mm, significantly smaller than that in the bilateral cordotomy group, which was 5.05 (4.52, 5.62) mm ( Z=-4.103, P<0.05). Among the GRBAS parameters, G (grade of hoarseness), B (breathiness), and A (asthenia), as well as VHI-10 scores and objective voice analysis parameters [jitter, shimmer, harmonic-noise ratio (HNR), and maximum phonation time (MPT)], were significantly better in the unilateral cordotomy group compared to the bilateral cordotomy group, with statistically significant differences ( P<0.05). Conclusions:Unilateral posterior vocal cord resection using CO 2 laser is simple and feasible for the treatment of bilateral vocal cord paralysis, with shorter recovery time, maximal preservation of laryngeal phonatory function, and fewer complications compared to bilateral resection. However, the one-time extubation rate is higher with bilateral resection, reducing the need for a second surgery and associated patient discomfort. This study offers guidance for clinical decision-making in the surgical management of bilateral vocal cord paralysis.
3.Analysis on the effect of different surgical methods on patients with severe cervical spondylotic myelopathy
Feng MIAO ; Xiangqiang WANG ; Zuqing YANG
Clinical Medicine of China 2017;33(11):1022-1025
Objective To compare the causes of poor effects after surgical treatment for severe cervical spondylotic myelopathy,and to analyze the clinical value of posterior surgery in the treatment of severe cervical spondylotic myelopathy.Methods From September 2013 to November 2016,ninety-two patients with severe cervical myelopathy in Shiyan Medical Hospital were selected as the research object,the patients were divided into the observation group and the control group,50 cases in each group,according to the different surgical methods,the control group received anterior cervical discectomy and interbody fusion and internal fixation treatment,the observation group was treated with cervical posterior decompression surgical treatment,the prognosis and the changes of cervical vertebra function in the two groups were recorded.Results There were statistically significant differences between the two groups in terms of operation time,intraoperative blood loss and postoperative hospital stay(t=5.392,7.114,4.552,P<0.05).The intervertebral height at 1 month after surgery in the observation group and the control group were(4.92 ± 1.51)mm and(4.26 ± 1.32)mm,significantly lower than those before the operation((3.72±0.42)mm,(3.78±0.93)mm)(t=10.495,6.114,P<0.05) .At 1 month after operation,the intervertebral height of the observation group was significantly higher than that of the control group(t=4.521,P<0.05).The excellent and good rate of JOA score of the observation group and control group at 1 month after operation were 97.6% and 84.0%,respectively,and the rate of the observation group was significantly higher than that of the control group(χ2=4.797,P<0.05).In the observation group and the control group,there were 1 case of throat pain after operation,and they were relieved after suitable treatment.Conclusion Compared with the anterior approach,the posterior treatment of severe cervical spondylotic myelopathy can reduce the trauma of patients,promote the recovery of intervertebral height and improve the function of the cervical spine,so as to achieve better results.

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