Creutzfeldt-Jakob disease is an extremely rare neurodegenerative disease. Due to the lack of specificity of its clinical symptoms, early diagnosis is difficult; Some patients often initially visit the mental health department because they may present psychological symptoms, that are easy misdiagnosed as a mental disorder. This article reports a case with emotional disturbance as the initial symptoms, the early diagnosis as a mental disorder, and the final diagnosis as probable sporadic Creutzfeldt-Jakob disease to improve awareness of this disease.

Creutzfeldt-Jakob disease is an extremely rare neurodegenerative disease. Due to the lack of specificity of its clinical symptoms, early diagnosis is difficult; Some patients often initially visit the mental health department because they may present psychological symptoms, that are easy misdiagnosed as a mental disorder. This article reports a case with emotional disturbance as the initial symptoms, the early diagnosis as a mental disorder, and the final diagnosis as probable sporadic Creutzfeldt-Jakob disease to improve awareness of this disease.

ObjectiveTo evaluate reliability and psychiatric clinical value of quantum resonance spectrometer (QRS) application in depression symptoms detection.MethodsThe psychiatric symptoms of 97 cases respectively obtained from QRS test and psychiatrist check were performed comparative analysis.The detecting order and checking order was under an order of go to see doctor random.ResultsSensitivity and negative predictive value of QRS were 100％ same as psychiatrists'examination in eating disorders; also specificity and positive predictive were 100％ in depressed mood,will weaken and sleep disorders.Kappa values were all greater than 0.8 of QRS in slow thinking,depressed mood,will weaken and other symptoms.The AUC of ROC line were all greater than 0.9 of QRS in slow thinking,depressed mood,will weaken,et al.11 symptoms.ConclusionQRS could be used as secondary depression diagnostic tools,provide a new basis for clinical diagnosis.