1.Effects of Remote Versus In-hospital Rehabilitation Training on Motor Function and Quality of Life in Patients with Parkinson's Disease: A Retrospective Cohort Study
Ying GE ; Wowa ZHAO ; Lu ZHANG ; Xiaoyi ZHAO ; Xuan SHU ; Jiawei LI ; Ying LIU
Medical Journal of Peking Union Medical College Hospital 2025;17(2):438-444
To compare the efficacy of remote rehabilitation training versus in-hospital rehabilitation training in improving motor function and quality of life in patients with Parkinson's disease (PD). Clinical data of PD patients who underwent remote or in-hospital rehabilitation at Peking Union Medical College Hospital between April 2021 and December 2023 were retrospectively collected. Both groups received structured rehabilitation training three times per week for four consecutive weeks. The remote rehabilitation group performed home-based exercises supervised via a mobile APP, while the in-hospital group underwent therapist-guided training in the hospital. Motor function was assessed before and after treatment using the Berg Balance Scale (BBS), Timed Up&Go Test (TUGT), Five Times Sit-to-Stand Test (FTSST), Unified Parkinson's Disease Rating Scale Part Ⅲ (UPDRS-Ⅲ), and wearable gait analysis. Daily living activities and quality of life were evaluated using UPDRS-Ⅱ and the 39-item Parkinson's Disease Questionnaire (PDQ-39). A total of 107 eligible PD patients were enrolled, including 59 in the remote rehabilitation group and 48 in the in-hospital group. In the remote group, UPDRS-Ⅲ scores improved from 18.20±9.22 to 15.34±7.82, and BBS scores increased from 48.25±6.07 to 51.27±4.50 (both Both remote and in-hospital rehabilitation significantly improve motor function and quality of life in PD patients. However, in-hospital rehabilitation demonstrates superior efficacy in enhancing balance, physical mobility, and quality of life compared to remote rehabilitation.
2.Motor function and quality of life in Parkinson's disease patients with freezing of gait
Ying GE ; Wowa ZHAO ; Lu ZHANG ; Xuan SHU ; Jiawei LI ; Ying LIU
Chinese Journal of Rehabilitation Theory and Practice 2024;30(3):339-344
Objective To observe the differences in motor function and quality of life among mild-to-moderate Parkinson's disease(PD)patients with or without freezing of gait(FOG),and the correlation of FOG to motor function and quality of life. Methods From April,2021 to December,2022,132 mild-to-moderate PD patients aged 60 to 80 years were selected from Peking Union Medical College Hospital,and were divided into FOG group(n = 43)and non-FOG group(n = 89)according to the clinical features.They were assessed with Freezing of Gait Questionnaire(FOGQ),Berg Balance Scale(BBS),Timed"Up&Go"Test(TUGT),Five Times Sit to Stand Test(FTSST),isokinetic muscle strength,Unified Parkinson's Disease Rating Scale(UPDRS)and 39-item Parkinson's Disease Question-aire-39(PDQ-39). Results The BBS score was lower(Z =-2.354,P<0.05),and the TUGT,FTSST,UPDRS part 2 and part 3 scores,and the Parkinson's disease summary index(PDSI)were higher in FOG group than in non-FOG group(Z>3.074,t = 2.748,P<0.01).FOGQ score correlated with BBS score,UPDRS Part 2 and Part 3 scores,and PDSI(|r|>0.392,P<0.001). Conclusion FOG would impair motor function,activities of daily living and quality of life in mild-to-moderate PD pa-tients,and increase the risk of falls.
3.Advances in the Evaluation of Freezing of Gait in Parkinson's Disease
Ying GE ; Wowa ZHAO ; Ying LIU
Medical Journal of Peking Union Medical College Hospital 2023;15(3):642-648
Freezing of gait (FOG) is a common motor manifestation in the middle and late stages of Parkinson's disease. It is also a major cause of falls and may lead to disability, making it important to identify and treat FOG effectively. In this paper, we review the common and practical methods of FOG detection in clinical and research studies, with a view to provide clinical reference.
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