1.Serous Cystadenocarcinoma of the Paratestis: A Rare Presentation of a Müllerian Tumor in an Elderly Filipino Male
Xhyrel June J. Tagaylo ; Jeffrey S. So ; Steffanie Charlyne A. Tamayo ; Patricia Danielle V. Dayrit ; Angelo Gabriel P. Profeta ; Neil Patrick Jose L. Samson ; Macario S. Vjuan S. Vjuan
Philippine Journal of Pathology 2026;(75th PSP Research Competition Abstracts):1-
Introduction:
Müllerian tumors are rare in males, with serous tumors representing
the most often subtype with only 50 cases documented. Excluding the benign/
borderline counterparts, only 29 are reported as primary malignant testicular masses
and only 4 are reported in the elderly. Due to rarity, there is no exact consensus in the
optimal grouping and management of these patients. Herein we report a case of serous
cystadenocarcinoma of the paratestis in an elderly Filipino male.
Case Description:
A 66 y/o male presented with scrotal enlargement. He had
previously undergone a Hartmann’s procedure for fecal impaction. An incidental
finding of a complicated hydrocele was noted on CT scan done few months prior his
scheduled colostomy takedown. He was subsequently referred to urology service for
evaluation. Tumor markers (AFP and βHCG) were all normal. One month prior to
admission, a marked increase in the size of the right scrotum was observed, prompting
decision to proceed with surgery.
Discussion:
Orchiectomy specimen evaluation requires careful assessment of tumor
appearance, location, and extent. In this case, the tumor arises in the paratestis without
involvement of the testicular parenchyma, showing solid and cystic areas with papillary
excrescences. The tumor showed enlarged, hyperchromatic nuclei with irregular
contours, abundant cytoplasm, and psammoma bodies. IHC revealed negative for
calretinin, glypican3, CDX2, SATB2, and CK20, but positive for CK7, Pax8, ER, and
WT1. Paratesticular serous cystadenocarcinoma diagnosis was made after carefully
ruling-out mesothelioma, YST and/or metastases. P53 staining was equivocal, with 5%
of cells positive amid broad negativity. Molecular testing was advised for grading and
prognosis.
Conclusion
Serous cancers are rare in males and must require IHC for diagnosis and
radical surgery due to high resistance to other treatments. Hydrocele being a frequent
finding can sometimes delay the diagnosis. Careful monitoring remains critical for
detecting progression and metastasis.
Cystadenocarcinoma, Serous
;
Orchiectomy
2.The Efficacy of Simultaneous Breast Reconstruction and Contralateral Balancing Procedures in Reducing the Need for Second Stage Operations.
Mark L SMITH ; Emily M CLARKE-PEARSON ; Michael VORNOVITSKY ; Joseph H DAYAN ; William SAMSON ; Mark R SULTAN
Archives of Plastic Surgery 2014;41(5):535-541
BACKGROUND: Patients having unilateral breast reconstruction often require a second stage procedure on the contralateral breast to improve symmetry. In order to provide immediate symmetry and minimize the frequency and extent of secondary procedures, we began performing simultaneous contralateral balancing operations at the time of initial reconstruction. This study examines the indications, safety, and efficacy of this approach. METHODS: One-hundred and two consecutive breast reconstructions with simultaneous contralateral balancing procedures were identified. Data included patient age, body mass index (BMI), type of reconstruction and balancing procedure, specimen weight, transfusion requirement, complications and additional surgery under anesthesia. Unpaired t-tests were used to compare BMI, specimen weight and need for non-autologous transfusion. RESULTS: Average patient age was 48 years. The majority had autologous tissue-only reconstructions (94%) and the rest prosthesis-based reconstructions (6%). Balancing procedures included reduction mammoplasty (50%), mastopexy (49%), and augmentation mammoplasty (1%). Average BMI was 27 and average reduction specimen was 340 grams. Non-autologous blood transfusion rate was 9%. There was no relationship between BMI or reduction specimen weight and need for transfusion. We performed secondary surgery in 24% of the autologous group and 100% of the prosthesis group. Revision rate for symmetry was 13% in the autologous group and 17% in the prosthesis group. CONCLUSIONS: Performing balancing at the time of breast reconstruction is safe and most effective in autologous reconstructions, where 87% did not require a second operation for symmetry.
Anesthesia
;
Blood Transfusion
;
Body Mass Index
;
Breast
;
Breast Neoplasms
;
Female
;
Free Tissue Flaps
;
Humans
;
Mammaplasty*
;
Prostheses and Implants


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