Objective:To investigate the clinical efficacy of hyperbaric oxygen（HBO）comprehensive treatment of sudden sensorineural hearing loss（SSHL）and the related influencing factors.Methods:A total of 310 SSHL patients admitted to PLA No.971 Hospital from January 2017 to June 2019 were selected and divided into control group（ n=154）and observation group（ n=156）. The control group was on medication only，while the observation group was treated with medication combined with HBO. The therapeutic effects were compared between the two groups. The rank sum test was adopted to test the significance of gender，age，comorbid diabetes mellitus（DM），hypertension，onset to treatment time（OTT），type of hearing loss curve，and degree of hearing impairment between the patients whose treatment was effective and those whose treatment was ineffective in the observation group. Logistic regression was used to analyze the independent factors affecting the prognosis. Results:After treatment，the total effective rate was 80.33% in the observation group and 66.90% in the control group，and there were statistically significant differences between the two groups（ P<0.05）. Among the patients in the observation group，there was no statistically significant difference between those whose treatment was effective and those whose treatment was ineffective in terms of gender，DM，and hypertension（ P>0.05），while there were statistically significant differences in terms of age，OTT，type of hearing loss curve，and degree of hearing loss（ P<0.05）. The results of logistic regression analysis showed that the OTT and the type of hearing loss curve were the independent influencing factors for the HBO comprehensive treatment of SSHL. Conclusion:HBO comprehensive treatment has obvious curative effects in treating SSHL. The OTT and the type of hearing loss curve are the influencing factors of the clinical efficacy of HBO combined with medication in treating SSHL．

Objective:To investigate the clinical efficacy of hyperbaric oxygen（HBO）comprehensive treatment of sudden sensorineural hearing loss（SSHL）and the related influencing factors.Methods:A total of 310 SSHL patients admitted to PLA No.971 Hospital from January 2017 to June 2019 were selected and divided into control group（ n=154）and observation group（ n=156）. The control group was on medication only，while the observation group was treated with medication combined with HBO. The therapeutic effects were compared between the two groups. The rank sum test was adopted to test the significance of gender，age，comorbid diabetes mellitus（DM），hypertension，onset to treatment time（OTT），type of hearing loss curve，and degree of hearing impairment between the patients whose treatment was effective and those whose treatment was ineffective in the observation group. Logistic regression was used to analyze the independent factors affecting the prognosis. Results:After treatment，the total effective rate was 80.33% in the observation group and 66.90% in the control group，and there were statistically significant differences between the two groups（ P<0.05）. Among the patients in the observation group，there was no statistically significant difference between those whose treatment was effective and those whose treatment was ineffective in terms of gender，DM，and hypertension（ P>0.05），while there were statistically significant differences in terms of age，OTT，type of hearing loss curve，and degree of hearing loss（ P<0.05）. The results of logistic regression analysis showed that the OTT and the type of hearing loss curve were the independent influencing factors for the HBO comprehensive treatment of SSHL. Conclusion:HBO comprehensive treatment has obvious curative effects in treating SSHL. The OTT and the type of hearing loss curve are the influencing factors of the clinical efficacy of HBO combined with medication in treating SSHL．