Objective:To explore the classification characteristics of the resilience of infertile women, and to analyze the distribution differences of each category in demographic and disease-related variables such as education level and type of infertility.Methods:Using convenient sampling method and cross-sectional survey, 400 infertile women in the Reproductive Medicine Center of the First Affiliated Hospital of Soochow University were assessed with the scale CD-RISC-10 from September 2019 to December 2020. The potential categories of resilience were analyzed, and then multivariate logistic regression was used to analyze the demographic and disease-related characteristics of different categories.Results:The resilience of infertile women can be divided into 3 potential categories: "low tenacity class" (group C1), "high tenacity class" (group C2) and "general resilience but low strength class" (group C3), accounting for 21.8% (87/400), 37.5% (150/400) and 41.8% (163/400) of the total respectively. Multivariate logistic regression analysis showed that there were significant differences in marriage duration type of infertility and the sense of fear or helplessness between group C1 and group C2 (<3.0 years vs. ≥7.0 years, P=0.019; P=0.045; P=0.015); there was a significant difference in marriage duration between group C1 and group C3 (<3.0 years vs. ≥7.0 years, P=0.039; 3.0-4.9 years vs. ≥7.0 years, P=0.024); there was a significant difference in education level between group C2 and group C3 (Junior high school or technical secondary school vs. Bachelor degree or above, P=0.003; Junior college vs. Bachelor degree or above, P=0.030). Conclusion:The resilience of infertile women has obvious sub category characteristics. There are differences in the distribution of education level, marriage duration type of infertility and the sense of fear or helplessness among different groups of infertile women. We should pay attention to the infertile women with low education level, short marriage time, primary infertility, strong sense of fear or helplessness, and adopt reasonable intervention to improve their resilience.

Objective:To explore the classification characteristics of the resilience of infertile women, and to analyze the distribution differences of each category in demographic and disease-related variables such as education level and type of infertility.Methods:Using convenient sampling method and cross-sectional survey, 400 infertile women in the Reproductive Medicine Center of the First Affiliated Hospital of Soochow University were assessed with the scale CD-RISC-10 from September 2019 to December 2020. The potential categories of resilience were analyzed, and then multivariate logistic regression was used to analyze the demographic and disease-related characteristics of different categories.Results:The resilience of infertile women can be divided into 3 potential categories: "low tenacity class" (group C1), "high tenacity class" (group C2) and "general resilience but low strength class" (group C3), accounting for 21.8% (87/400), 37.5% (150/400) and 41.8% (163/400) of the total respectively. Multivariate logistic regression analysis showed that there were significant differences in marriage duration type of infertility and the sense of fear or helplessness between group C1 and group C2 (<3.0 years vs. ≥7.0 years, P=0.019; P=0.045; P=0.015); there was a significant difference in marriage duration between group C1 and group C3 (<3.0 years vs. ≥7.0 years, P=0.039; 3.0-4.9 years vs. ≥7.0 years, P=0.024); there was a significant difference in education level between group C2 and group C3 (Junior high school or technical secondary school vs. Bachelor degree or above, P=0.003; Junior college vs. Bachelor degree or above, P=0.030). Conclusion:The resilience of infertile women has obvious sub category characteristics. There are differences in the distribution of education level, marriage duration type of infertility and the sense of fear or helplessness among different groups of infertile women. We should pay attention to the infertile women with low education level, short marriage time, primary infertility, strong sense of fear or helplessness, and adopt reasonable intervention to improve their resilience.

Objective To explore the application value of single-door laminoplasty via Y type nano-bone plate in treating multilevel cervical spondylotic myelopathy (MCSM) and analyze the short-term efficacy.Methods From January 2013 to December 2016,79 cases of MCSM were treated with single-door laminoplasty via Y type nano-bone plate to evaluate the improvement of post-operative neurological function by the Japanese Orthopaedic Association (JOA) evaluation system.We also measured cervical curvature of cervical X-ray and C5 sagittal diameter of the spinal canal before operation and 6 months after operation to understand the maintenance and enlargement of the spinal canal.The improvement degree of spinal cord compression was evaluated by preoperative and postoperative cervical MRI.Osseous healing on the open door side and the door shaft side was observed with the aid of three-dimensional spiral CT.Results Follow-up ranged from 6 to 36 months,with an average of (20.4±7.9)months.Preoperative JOA score was (8.6 ± 1.3) points and JOA score 6 months after operation was (14.3 ± 1.5)points (P ＜ 0.05).JOA improvement rate was (68.6 ± 15.8)％;postoperative follow-up X-ray and threedimensional spiral CT showed that the spinal canal had satisfying enlargement,the door shaft side all had osseous healing,the open door side osseous healing was not obvious,and there was no lamina collapse or reclosing.Sagittal diameter of theC spinal canal was (8.9±l.1)mm before operation and (15.1±l.1)mm 6 months after operation (P＜0.05).The spinal canal enlargement rate was (70.8±22.3)％,cervical curvature was (14.8± 7.0)°preoperatively and (15.1±6.7)°postoperatively with no significant difference (P＞0.05).Conclusion EOLP via Y type nano-bone plate is safe and efficacious in treating MCSM.It not only provides a good immediate fixation,but also provides the possibility for the open door side lateral osseous fusion.

Objective To establish a methamphetamine-dependent model in zebrabfish.Methods On the basis of conditioned place preference (CPP) in drug-dependent experiment,place preference box for zebrafishes was designed.According to the natural characteristics of zebrafishes,their preference side and non-preferred side were determined.After intraperitoneal injection of methamphetamine,zebrafishes were placed in non-preferred side(drug box).After intraperitoneal injection of normal saline,zebrafishes were placed in preference side (non-drug box).CPP training was five days and then the methamphetamine-induced place preference in zebrafish were observed.Results After five days training,the staying time of zebrafishes of control group in drug box was not significantly lengthened to compared with before training(.( 287.5 ± 80.18 ) s,(276.3 ± 85.04) s),P＞ 0.05 ).The staying time of zebrafishes of model group in drug box was markedly extended after training.In comparison with before training or control group,the significant differences were observed ( (465.5 ± 113.49 ) s,( 247.9 ±95.62)s,(276.3 ±85.04)s,P＜0.01).Conclusion Methamphetamine can induce conditioned place preference in zebrafishes.The CPP model in zebrafish established in this study can be used as a new animal model in drug dependence.