Objective To investigate the predictive value of systemic immune-inflammation index(SII)and N-terminal pro-brain natriuretic peptide(NT-proBNP)level in elderly patients with acute ST-segment elevation myocardial infarction(STEMI)developing contrast-induced acute kidney injury(CIAKI)after PCI.Methods A total of 1085 elderly STEMI patients undergoing emergency PCI in the Affiliated Hospital of Xuzhou Medical University from January 2018 to March 2023 were consecutively recruited as a training set,and another 287 elderly STEMI pa-tients receiving emergency PCI in the East Branch of the Affiliated Hospital from January 2021 to June 2023 were included as a verification set.According to the diagnostic criteria of CIAKI,they were divided into CIAKI group(n=95)and non-CIAKI group(n=990).Based on the results of restricted cubic spline(RCS)analysis,the patients from the training set were assigned into low-risk subgroup(n=292),moderate-risk group(n=515)and high-risk group(n=278).Multivari-ate logistic regression analysis was used to analyze the independent risk factors of CIAKI in elder-ly STEMI patients after PCI,and ROC curve was plotted to analyze the predictive value of combi-nation of SII and NT-proBNP.The risk of CIAKI was compared among the patients at different risk grades.Results Age,SII,baseline serum creatinine,NT-proBNP,fasting blood glucose and use of diuretics were independent risk factors for CIAKI after primary PCI in elderly STEMI patients(P＜0.05,P＜0.01).The AUC value of SII combined with NT-proBNP in predicting CIAKI was 0.801(95％CI:0.761-0.842,P＜0.01),with a sensitivity of 83.2％and a specificity of 67.5％,both superior to that of SII or NT-proBNP alone.RCS analysis revealed an increased risk of CIAKI at SII ≥1084.97 × 109/L and NT-proBNP ≥296.12 ng/L.The incidence of CIAKI was increased with the increase of risk grades(1.71％vs 6.41％vs 20.50％).Conclusion SII and NT-proBNP are independent risk factors for CIAKI after emergency PCI in elderly STEMI pa-tients.And their combination has better predictive value for CIAKI.

Objective To investigate the predictive value of Cys C and AT Ⅲ for CIAKI in elderly hypertensive patients with AMI after PCI.Methods A total of 911 elderly hypertensive patients with AMI undergoing emergency PCI in the Affiliated Hospital of Xuzhou Medical University from January 2019 to May 2023 were consecutively enrolled,and then randomly divided into a training group(731 cases)and a validation group(180 cases)in a ratio of 8∶2.According to the diagnostic criteria of CIAKI defined by the European Society of Urogenital Radiology,the patients of the training group were further divided into CIAKI subgroup(n=91)and non-CIAKI sub-group(n=640).The basic clinical data were compared between the CIAKI and non-CIAKI sub-groups and between the training and validation groups.Multivariate logistic regression analysis was used.ROC curve was drawn to analyze the predictive value of Cys C,ATⅢ and their combina-tion for CIAKI.Results Fasting blood glucose,TG,Cys C,and diuretics were independent risk factors(OR=1.116,95％CI:1.009-1.235;OR=1.786,95％CI:1.363-2.339;OR=13.360,95％CI:4.462-39.999;OR=10.606,95％CI:4.110-27.370),while LVEF and AT Ⅲ were protective factors(OR=0.932,95％CI:0.897-0.968;OR=0.949,95％CI:0.929-0.969)for CIAKI in eld-erly hypertensive patients after emergency PCI.The AUC value of Cys C and AT Ⅲ combined to-gether in predicting CIAKI after emergency PCI was 0.818(95％CI:0.773-0.863,P＜0.01),which was better than either of them alone.When Cys C level ≥1.10 mg/L,the risk of CIAKI was increased with the increment of the level;when AT Ⅲ ≥69％,the risk of CIAKI was decreased with the increase of AT Ⅲ level.Conclusion High Cys C level and low AT Ⅲ level are independ-ent risk factors for CIAKI,and their combination can improve the accuracy of predicting CIAKI after emergency PCI in elderly patients with hypertensive AMI.

Objective:To investigate the status of sleep quality and regulatory emotional self-efficacy of in vitro fertilization-embryo transfer (IVF-ET) patients and to analyze the relationship between the two indicators. Methods:From February to November 2019, a cross-sectional study including 156 female IVF-ET patients entering the cycle in the Department of Reproduction of the First Affiliated Hospital of Nanchang University was performed. Chinese version of the Emotional Regulation Self-efficacy Scale (RES-C) and Pittsburgh Sleep Quality Index (PSQI) were used to investigate their emotional regulation self-efficacy and sleep quality.Pearson correlation analysis was used to analyze their relationship.Results:The detection rate of poor sleep quality in 156 patients (44.9%, 70/156) was higher than that in normal person (13.20%-33.92%). The age, education, place of residence, infertility duration, family income, occupation, repeated cycle were correlated with poor sleep quality ( P=0.004, P=0.013, P=0.014, P=0.007, P=0.001). Emotional regulation self-efficacy score (38.51±8.74) was lower than norm (45.08±6.96) ( t=-9.360, P<0.001). The total score of PSQI (7.56±1.81) was significantly higher than the norm (2.52±1.60) ( t=16.076 , P<0.001), the score of all factors except hypnotic drugs was higher than the norm ( P<0.001). The score of regulatory emotional self-efficacy was negatively correlated with the total score of PSQI ( r=-0.564, P<0.001). Emotional self-efficacy, infertility duration and age had predictive effect on sleep quality. Conclusion:Since the sleep quality and self-efficacy of emotion regulation in IVF-ET patients are relatively low, medical staff should develop targeted psychological intervention to improve patients' ability of emotional regulation and effectively improve their sleep quality, so as to achieve better outcomes of pregnancy aid treatment.

Objective:To investigate the status of sleep quality and regulatory emotional self-efficacy of in vitro fertilization-embryo transfer (IVF-ET) patients and to analyze the relationship between the two indicators. Methods:From February to November 2019, a cross-sectional study including 156 female IVF-ET patients entering the cycle in the Department of Reproduction of the First Affiliated Hospital of Nanchang University was performed. Chinese version of the Emotional Regulation Self-efficacy Scale (RES-C) and Pittsburgh Sleep Quality Index (PSQI) were used to investigate their emotional regulation self-efficacy and sleep quality.Pearson correlation analysis was used to analyze their relationship.Results:The detection rate of poor sleep quality in 156 patients (44.9%, 70/156) was higher than that in normal person (13.20%-33.92%). The age, education, place of residence, infertility duration, family income, occupation, repeated cycle were correlated with poor sleep quality ( P=0.004, P=0.013, P=0.014, P=0.007, P=0.001). Emotional regulation self-efficacy score (38.51±8.74) was lower than norm (45.08±6.96) ( t=-9.360, P<0.001). The total score of PSQI (7.56±1.81) was significantly higher than the norm (2.52±1.60) ( t=16.076 , P<0.001), the score of all factors except hypnotic drugs was higher than the norm ( P<0.001). The score of regulatory emotional self-efficacy was negatively correlated with the total score of PSQI ( r=-0.564, P<0.001). Emotional self-efficacy, infertility duration and age had predictive effect on sleep quality. Conclusion:Since the sleep quality and self-efficacy of emotion regulation in IVF-ET patients are relatively low, medical staff should develop targeted psychological intervention to improve patients' ability of emotional regulation and effectively improve their sleep quality, so as to achieve better outcomes of pregnancy aid treatment.

Objective To evaluate the feasibility,effectiveness and safety of Carto3 three-dimensional electrophysiological mapping system in guiding radiofrequency ablation (RFA) for paroxysmal supraventricular tachycardia (PSVT).Methods The clinical data of a total of 28 patients with PSVT (Carto group),who received RFA guided by Carto3 three-dimensional electrophysiological mapping system during the period from March 2015 to February 2016,were retrospectively collected.Other 36 parents with PSVT,who received fluoroscopy-guided RFA during the period from March 2014 to February 2015,were collected as control group.The X-ray irradiation time,success rate of operation,operation time,complication and recurrence rate were calculated and the results were compared between the two groups.Results The mean fluoroscopy time in Carto group was (2.6±2.3) min,which was significantly less than (15.8±9.5) min in the control group (P＜0.001),and among them zero X-ray irradiation was obtained in 8 patients who had atrioventricular nodal reentrant tachycardia (AVNRT).The operation success rates of Carto group and the control group were 100％ (28/28) and 94.4％ (35/36) respectively (P＞0.05).The operation time in Carto group and the control group was (162.7±34.4) min and (149.4±46.2) min respectively (P＞0.05).In Carto group no any complications occurred,and in the control group one patient with AVNRT developed transient degree Ⅱ atrioventricular block during ablation process.All patients were followed up for 6 months,and no recurrence was observed in all patients of both groups.Conclusion For the treatment of PSVT,RFA guided by Carto3 three-dimensional electrophysiological mapping system is safe and effective,it can significantly reduce the X-ray irradiation time,even zero X-ray radiation in some AVNRT patients,meanwhile,this technique does not increase operation time and operation risk.