1.The relationship between AGI event grading and short-term prognosis in patients with acute ischemic stroke of different severity levels
Shaohui LIU ; Xi WU ; Siyuan WEI ; Zhixin WU ; Shaojuan HUANG ; Yi SU ; Yuanyi LI ; Wending FAN ; Qingyu WU
The Journal of Practical Medicine 2024;40(23):3323-3330
Objective To explore the grading of acute gastrointestinal injury(AGI)events in patients with different severities of acute ischemic stroke(AIS)and correlation of short-term prognosis.Methods AIS patients admitted from the Advanced Stroke Center of the Eighth Clinical Medical College of Guangzhou University of Chinese Medicine from January 2023 to November 2023 were retrospectively selected,and depending on the degree of nerve function defect(NIHSS)scores.AIS patients were divided into two groups:NIHSS ≤ 14 group and NIHSS>14 group.The National Institute of Health Stroke Scale(NIHSS)score,general baseline data,clinical test indicators,AGI event classification and short-term prognosis were collected at admission.Results A total of 270 patients were included,with an average age of(64.95±13.65)years,70.0%males and 30.0%females.The proportion of AIS patients with AGI incident accounted for 66.30%.AIS patients after AGI incidents,90 days after the onset of the modified Rankin rating scale(mRS)score>2 points of 83 people,accounting for 30.7%;The poor clinical outcomes of 270 AIS patients with different AGI event grades were significantly different(P<0.05),among which AGI grade 0 and AGI grade Ⅰ were significantly different from AGI grade Ⅲ and AGI grade Ⅳ,respectively.The incidence of poor prognosis of AGI grade Ⅲ and AGI grade Ⅳ is significantly higher than that of AGI grade 0 and AGI grade Ⅰ.In AIS patients with NIHSS>14 group,there were significant differences in the adverse clinical outcomes between AGI grade 0,AGI grade Ⅰ and AGI grade Ⅲ(P<0.05),and the incidence of poor prognosis of AGI grade Ⅲ was significantly higher than that of AGI grade 0 and AGI grade Ⅰ.Multivariate Logistic regression analysis showed that NIHSS score was an independent risk factor for AGI events in AIS patients(P<0.05).The higher the NIHSS score,the higher the risk of AGI events in AIS patients.And age,NIHSS score,systolic blood pressure is 90 days after AGI events affect AIS patients independent risk factors of poor prognosis(P<0.05),the higher the age,the greater the NIHSS score,the higher systolic blood pressure of patients with AIS 90 days after AGI events are at higher risk of poor prognosis.Conclusion AGI event grading in patients with AIS of different severity is associated with short-term prognosis.
2.The relationship between AGI event grading and short-term prognosis in patients with acute ischemic stroke of different severity levels
Shaohui LIU ; Xi WU ; Siyuan WEI ; Zhixin WU ; Shaojuan HUANG ; Yi SU ; Yuanyi LI ; Wending FAN ; Qingyu WU
The Journal of Practical Medicine 2024;40(23):3323-3330
Objective To explore the grading of acute gastrointestinal injury(AGI)events in patients with different severities of acute ischemic stroke(AIS)and correlation of short-term prognosis.Methods AIS patients admitted from the Advanced Stroke Center of the Eighth Clinical Medical College of Guangzhou University of Chinese Medicine from January 2023 to November 2023 were retrospectively selected,and depending on the degree of nerve function defect(NIHSS)scores.AIS patients were divided into two groups:NIHSS ≤ 14 group and NIHSS>14 group.The National Institute of Health Stroke Scale(NIHSS)score,general baseline data,clinical test indicators,AGI event classification and short-term prognosis were collected at admission.Results A total of 270 patients were included,with an average age of(64.95±13.65)years,70.0%males and 30.0%females.The proportion of AIS patients with AGI incident accounted for 66.30%.AIS patients after AGI incidents,90 days after the onset of the modified Rankin rating scale(mRS)score>2 points of 83 people,accounting for 30.7%;The poor clinical outcomes of 270 AIS patients with different AGI event grades were significantly different(P<0.05),among which AGI grade 0 and AGI grade Ⅰ were significantly different from AGI grade Ⅲ and AGI grade Ⅳ,respectively.The incidence of poor prognosis of AGI grade Ⅲ and AGI grade Ⅳ is significantly higher than that of AGI grade 0 and AGI grade Ⅰ.In AIS patients with NIHSS>14 group,there were significant differences in the adverse clinical outcomes between AGI grade 0,AGI grade Ⅰ and AGI grade Ⅲ(P<0.05),and the incidence of poor prognosis of AGI grade Ⅲ was significantly higher than that of AGI grade 0 and AGI grade Ⅰ.Multivariate Logistic regression analysis showed that NIHSS score was an independent risk factor for AGI events in AIS patients(P<0.05).The higher the NIHSS score,the higher the risk of AGI events in AIS patients.And age,NIHSS score,systolic blood pressure is 90 days after AGI events affect AIS patients independent risk factors of poor prognosis(P<0.05),the higher the age,the greater the NIHSS score,the higher systolic blood pressure of patients with AIS 90 days after AGI events are at higher risk of poor prognosis.Conclusion AGI event grading in patients with AIS of different severity is associated with short-term prognosis.

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