1.EFFECT OF FACIAL TREATMENT WITH HEATED STEAM ON DETECTION OF HUMAN DEMODEX MITES
Yu-Zhu LAI ; Yan HONG ; Jun QI ; Zhi-Cheng LUO ; Wen-Ting LENG
Acta Parasitologica et Medica Entomologica Sinica 2024;31(3):172-176
Objective The aim of this study was to investigate the potential impact of facial heated steam treatment on the Demodex mite detection rate.Methods Overall,215 patients to suspected demodicidosis who visited the dermatology outpatient department of a tertiary hospital in Lanzhou between May and July 2023 were selected as study subjects.The facial skin scraping method was employed following no pretreatment or heated steam treatment for 10 min to detect facial Demodex.Results The Demodex mite detection rate was significantly(χ2=54.07,P=0.00)higher with heated steam facial treatment(63.7%,137/215)compared to no pretreatment(28.4%,61/215).Conclusions The results indicate a statistically significant difference in the detection rate of human Demodex mites between patients who received facial heated steam treatment and those who did not.These findings provide a novel reference for experimental diagnostic methods of demodicosis.
2.Treatment of Adult Chronic Insomnia and the Effect of Assisting Benzodiazepine Withdrawl with a Combination of Suanza-oren Decoction and Huanglian Wendan Decoction:A Multicenter,Prospective Cohort Study
Si-Yu YANG ; Xiu-Mei LENG ; Jin LIU ; Wen-Hua XU ; Yong-Gui YUAN ; Li-Xia SUN ; Yong LI ; Zheng-Hua HOU ; Zhi XU ; Heng DAI ; Su-Zhen CHEN ; D.Reinhardt JAN ; Xin-Yu DU ; Xin-Ran XU ; Jin ZHONG ; Jing ZHANG ; Ting WU ; Xiu-Qin WANG
Journal of Nanjing University of Traditional Chinese Medicine 2023;39(12):1224-1231
OBJECTIVE To explore the efficacy of Sour Jujube Seed Decoction combined with Huanglian Wendan Decoction on adult chronic insomnia and its effect on hypnotic withdrawal.METHODS 187 patients with chronic insomnia were included for anal-ysis,including 102 in the traditional Chinese medicine(TCM)group and 85 in the western medicine group.The TCM group was trea-ted with Sour Jujube Seed Decoction combined with Huanglian Wendan Decoction,while the western medicine group was treated with benzodiazepine under the consideration of doctor.The intervention period was 1 month,with assessments using the Pittsburgh Sleep Quality Index(PSQI)conducted before and after the intervention.Follow-up evaluations were performed at 3 months and 6 months re-spectively after the intervention.RESULTS There was no significant difference between the two groups at baseline.After the inter-vention,the PSQI scores of patients in both groups were significantly improved(P<0.01).Among them,the TCM group was better than the western medicine group in the improvement of sleep quality and sleeping pills,total PSQI score reduction(P<0.01).The re-sults of linear regression analysis showed that after controlling for confounding factors,the regression coefficients of the TCM group in two different models were1.821 and 1.922 respectively,and the former was statistically significant(P<0.05).By screening patients who took hypnotics at baseline in the TCM group and comparing them with those in the western medicine group,the influencing factors of hypnotic withdrawal were analyzed.During the 3-month follow-up,25 out of 39 patients in the TCM group and 17 out of 80 patients in the western medicine group had hypnotic withdrawal(χ2= 19.25,P<0.001);during the 6-month follow-up,23 of the 39 patients in the TCM group and 18 of the 79 patients in the western medicine group had hypnotic withdrawal(χ2= 13.53,P<0.001),the with-drawal rate of patients in the TCM group was significantly higher than that in the western medicine group.Further regression analysis showed that after adjusting for confounding factors,the results showed that the western medicine group had a significantly higher rate of not withdrawal than the TCM group at 3 months(OR=5.50,95%CI:2.30~13.72)and 6 months(OR=6.43,95%CI:2.54~17.77),and the results were statistically different(P<0.05).CONCLUSION Sour Jujube Seed Decoction combined with Huangli-an Wendan Decoction is effective in treating adult chronic insomnia and assisting in hypnotic withdrawal.
3.Analysis on clinical laboratory indicators of different prognostic patients with severe fever with thrombocytopenia syndrome
Hong-yan ZHANG ; Gui-liu CHEN ; Wen-ting LI ; Rui-xue LENG ; Wei-zi QIN
Chinese Journal of Disease Control & Prevention 2020;24(3):365-368
Objective To analyze the clinical laboratory indicators of severe fever with thrombocytopenia syndrome( SFTS) patients caused by novel Bunyavirus infection,and focus on comparing the indicators of severe patients with different prognosis. The findings may help to predict poor prognosis for severe patients in the early stage. Methods The clinical laboratory indicators of all diagnosed confirmedly patients in two Hospitals,from January 2011 to December 2018,and the differences between groups were analyzed.Results A total of 168 clinically diagnosed SFTS cases ( 117 cases of non-severe cases and 51 cases of severe cases) were included in this study. In the severe cases,the prognosis was improved in 30 cases and the prognosis was poor in 21 cases. The laboratory indicators of severe patients with different prognosis were compared. The data showed that the levels of several indicators in patients with poor prognosis were statistically different with these in patients with better prognosis. In addition,the proportion of coma,diffuse intravascular coagulation and heart failure in patients with poor prognosis was significantly higher than that in patients with improved prognosis ( all P<0. 05) . Conclusion Differentiated prevention and treat- ment strategies should be developed for severe patients with possible poor prognosis.
4.A nationwide, resident-led teaching programme for medical students in Singapore: SingHealth Student Internship Programme Bootcamp.
Daniel Sw TING ; Jill Cs LEE ; Benny Kg LOO ; Katherine BAISA ; Wen Hsin KOO ; Sandy COOK ; Boon Leng LIM
Singapore medical journal 2016;57(5):233-237
INTRODUCTIONThis study aimed to describe the planning, development and evaluation of the success of the first nationwide, resident-led, large-group teaching programme for medical students - the Singapore Health Services Student Internship Programme (SIP) Bootcamp.
METHODSThis was an initial feasibility study evaluating a half-day teaching boot camp initiated, developed and conducted by the resident educators. A three-month preparation period was required to set up an education subcommittee, liaise with medical student leaders, recruit resident educators, meet all the stakeholders and conduct the boot camp. During the SIP Bootcamp, resident educators conducted clinical case presentations using a question-and-answer format. Audience participation was strongly encouraged. A 15-item questionnaire was distributed to assess the participants' learning experience and the resident educators' teaching performance using a five-point Likert scale.
RESULTSOverall, 94.8% (n = 110) of the 116 respondents agreed that the teaching sessions were of high quality and content was relevant to their training. The resident educators appeared well-informed (96.6%, n = 112) and enthusiastic about their respective topics (98.3%, n = 114). However, a few students (9.5%, n = 11) felt that the audio-visual aids and handouts could be improved to better aid their learning process.
CONCLUSIONThis teaching boot camp for medical students was the first of its kind in Singapore and feedback from medical students showed that it was well-received. Further research using different teaching methods, including small-group discussions and surgical practical sessions by resident educators from different specialties, would be of great value to students.
Clinical Competence ; Curriculum ; Education, Medical ; methods ; organization & administration ; Feasibility Studies ; Humans ; Internship and Residency ; Schools, Medical ; Singapore ; Students, Medical ; Surveys and Questionnaires

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