Bladder paraganglioma is a rare neuroendocrine tumor, accounting for only 0.05% of all bladder tumors. This article reports the diagnosis and treatment of a 16-year-old male patient with acute hemorrhage secondary to a giant bladder paraganglioma(approximately 10 cm in maximum diameter). Preoperative imaging evaluation suggested locally advanced disease, and the patient subsequently received three cycles of neoadjuvant chemotherapy with temozolomide. He patient's blood tests revealed hemorrhagic shock. During the waiting period of surgery, hemostasis was successfully achieved through emergency transarterial embolization. Subsequently, the patient underwent emergency radical cystectomy combined with orthotopic ileal neobladder reconstruction under general anesthesia and recovered well after surgery. Postoperative pathological examination confirmed the diagnosis of bladder paraganglioma, with positive immunohistochemical staining for succinate dehydrogenase subunit B and a Ki-67 proliferation index of 3%. At the 6-week follow-up, the patient's blood pressure and endocrine parameters had returned to normal, with a satisfactory quality of life. This case demonstrates that a multidisciplinary team approach can effectively integrate expertise from various specialties to formulate comprehensive and systematic treatment plans, which is crucial for ensuring successful management of such complex cases.

Objective To explore the clinical efficacy of Indigo thrombus aspiration system in acute pulmonary embolism(APE).Methods Seventy APE patients were selected.All patients were treated with percutaneous mechanical thrombectomy(PMT),and the Indigo thrombus aspiration system was used during surgery.The clinical efficacy and the occurrence of complications after surgery were compared in patients.Results The total therapy effective rate after surgery for patients was 94.29％(66/70),of which 42 cases were significantly effective,24 cases were effective and 4 cases were ineffective.The occurrence rate of complications after surgery for patients was 8.57％(6/70),including bradycardia in 1 case,tachycardia in 1 case,arrhythmia in 1 case,hemorrhage in 2 cases and renal insufficiency in 1 case.Conclusion The clinical efficacy of Indigo thrombus aspiration system in APE is significant and has certain safety.

Humans ; Parkinson Disease/diagnosis* ; Machine Learning

Themedical's () infantgenre in western Hunan Province is one of the most famous infantgenres in China. Based on physiological and pathological characteristics of infants, generation-inhibition theory of five-elements andmedical's promotion-inhibition theory of five-meridians, theprotocol of "" was flexibly adjusted; according to different constitution types, including lung-deficiency type, spleen-deficiency type, kidney-deficiency type,-deficiency type,-deficiency type,-deficiency type, phlegm-wet type, phlegm-heat type, different protocols were adopted to prevent or reduce the asthma recurrence and reach the aim of regulating constitution and disease prevention.