Objective:To investigate the clinical effect of percutaneous transhepatic cholangial drainage (PTCD) combined with percutaneous transhepatic papillary balloon dilatation (PTPBD) in the treatment of choledocholithiasis.Methods:The clinical data of patients treated with PTCD combined with PTPBD under digital subtraction angiography for choledocholithiasis in the Interventional Department of the Second Affiliated Hospital of Nantong University from June 2021 to May 2024 were retrospectively analyzed, and a total of 90 patients were enrolled, including 58 males and 32 females, aged (56.6±4.3) years. The changes of liver function, postoperative complications, and prognosis were analyzed.Results:Of 90 patients were successfully treated with PTCD, and 3 patients (3.3%) died after PTCD operation, mainly due to old age combined with a variety of underlying diseases. 85(97.7%) of the remaining 87 patients were successfully treated with PTPBD, while 2 cases (2.3%) experienced technical failure due to excessive stone size (>20 mm). Among the 90 cases after the procedure, there were 6 cases (6.7%) of abdominal pain, 3 cases (3.3%) of bleeding, 4 cases (4.4%) of fever, and no serious complications such as bile duct perforation, intestinal perforation or pancreatitis occurred. The symptoms of 87 patients were improved within 3 to 7 days after PTCD. The changes of leukocyte, total bilirubin, alanine aminotransferase and C reactive protein before and after surgery were statistically significant (all P<0.001). Conclusions:PTCD combined with PTPBD is a minimally invasive treatment for common bile duct stones with obvious advantages in high success rate, safety, and effectiveness, which is especially suitable for elderly patients with multiple underlying diseases, inability to tolerate surgical procedures, or no suitable endoscopic pathways.

Objective To analyze the effect of percutaneous transhepatic cholangial drainage(PTCD)combined with percutaneous transhepatic papillary balloon dilation(PTPBD)in the treatment of common bile duct stone in elderly patients.Methods The clinical data of elderly patients treated with PTCD combined with PTPBD under digital subtraction angiography(DSA)for common bile duct stone were retrospectively collected,the changes in liver function,postoperative complications,and prognosis were analyzed.Results All 70 patients were successfully treated with PTCD,and other 3 patients died after PTCD operation,mainly due to severe infection combined with a variety of underlying diseases.Among the remaining 67 patients,65 cases(97.00%)were successfully treated with PTPBD,while other 2 cases(3.00%)experienced technical failure due to excessive stone size(>20 mm).Among the 70 cases after the pro-cedure,there were 5 cases with abdominal pain,2 cases with bleeding,4 cases with fever,and no serious complications occurred,such as bile duct perforation,intestinal perforation,or pancreatitis.The symptoms of 67 patients were improved from 3 to 7 days after PTCD,and the changes in leukocyte,total bilirubin,alanine aminotransferase and C-reactive protein before and after surgery were sta-tistically significant(P<0.05).Conclusion PTCD combined with PTPBD is a minimally invasive treatment method for common bile duct stone with a high success rate,safety,and effectiveness,which is especially suitable for elderly patients with multiple under-lying diseases,an inability to tolerate surgical and endoscopic treatments.It is worthy of clinical promotion and application.

Objective:To analyse the clinical effect of percutaneous transhepatic papillary balloon dilatation (PTPBD) combined with lithotriptic basket in the treatment of large-diameter common bile duct stone (CBDS) after percutaneous transhepatic cholangia drainage (PTCD).Methods:The clinical data of 50 patients treated with PTPBD combined with lithotriptic basket after PTCD under digital subtraction angiography (DSA) for large-diameter CBDS in the Department of Interventional Radiology, the Second Affiliated Hospital of Nantong University from October 2021 to September 2024 were retrospectively analyzed, including 38 males and 12 females, aged (57.6±3.6) years. Clinical data, including gender, age, long diameter of the stone, and surgery-related complications, were recorded. Changes in leukocyte count, total bilirubin, alanine transaminase and C-reactive protein were compared before PTCD and on the 5th postoperative day.Results:All 50 cases were successfully treated with PTCD. Significant improvements were observed in white blood cell count [(7.35±2.36)×10 9/L vs. (11.34±2.81)×10 9/L], total bilirubin [(27.58±6.24) μmol/L vs. (74.35±12.26) μmol/L], alanine transaminase [(41.25±8.65) U/L vs. (141.41±29.16) U/L] and C-reactive protein [(39.34±13.45) mg/L vs. (81.43±31.35) mg/L] before and after PTCD (all P<0.001). The time interval between PTCD and PTPBD was (14.46±1.01) d. Among the 50 patients, 48 cases (96.0%) were successfully treated with PTPBD combined with a lithotriptic basket, while 2 cases (4.0%) failed due to the basket's inability to retrieve the stones. Among the 50 patients after PTCD, 2 cases (4.0%) of abdominal pain, 2 cases (4.0%) of bleeding, and 2 cases (4.0%) of fever. Following PTPBD with lithotriptic basket stone removal, abdominal pain occurred in 3 patients (6.0%) and fever in 2 (4.0%). Conclusion:PTPBD combined with lithotriptic basket in the second stage after PTCD under DSA is a minimally invasive treatment for large-diameter CBDS with safety and effectiveness.

Objective To investigate the clinical effect of digital subtraction angiography(DSA)-guided percutaneous transhepatic cholangial drainage(PTCD)in treatment of acute obstructive suppurative cholangitis(AOSC).Methods The relevant data of DSA-guided PTCD in treatment of AOSC patients were collected to analyze its safety and effectiveness.Results Among the 70 patients,there were 2 cases of bleeding,1 case of drainage tube blockage,and 1 case of drainage tube detachment,and no other serious surgical related complications occurred.The symptoms of 66 patients were improved from 3 to 7 d after PTCD compared with those before PTCD,and 4 patients died during hospitalization.The average daily bile drainage volume of patients was(650±130)m L,and the changes of leukocyte,total bilirubin,alanine aminotransferase and alkaline phosphatase indexes before and after surgery were statisti-cally significant(P<0.05).Conclusion DSA-guided PTCD in treatment of AOSC is a safe and effective minimally invasive method with high technical success rate,which can timely relieve obstruction,improve symptoms,reduce mortality,and create opportunities and conditions for secondary surgery or interventional therapy.

Objective To investigate the clinical effect of percutaneous transhepatic papillary balloon dilation(PTPBD)in the treatment of common bile duct stone(CBDS).Methods The relevant data of patients treated with PTPBD for CBDS under digital subtraction angiography(DSA)were analyzed retrospectively,and its safety and effectiveness were analyzed.Results Among the 50 patients,there were 3 cases of abdominal pain,2 cases of bleeding,2 cases of fever,and no serious complications related to bile duct or intesti-nal perforation or pancreatitis.45 cases(90.00%)were successfully treated with PTPBD,while other 5 cases experienced technical failure due to excessive stone size(>20 mm).Conclusion PTPBD is a safe,effective,and minimally invasive treatment for CBDS with a high success rate,which is especially suitable for the patients with older age,multiple underlying diseases,inability to toler-ate surgical procedure,and without suitable endoscopic pathways,and the method is worthy of clinical promotion.

Objective To investigate the clinical effect of percutaneous transhepatic papillary balloon dilation(PTPBD)in the treatment of common bile duct stone(CBDS).Methods The relevant data of patients treated with PTPBD for CBDS under digital subtraction angiography(DSA)were analyzed retrospectively,and its safety and effectiveness were analyzed.Results Among the 50 patients,there were 3 cases of abdominal pain,2 cases of bleeding,2 cases of fever,and no serious complications related to bile duct or intesti-nal perforation or pancreatitis.45 cases(90.00%)were successfully treated with PTPBD,while other 5 cases experienced technical failure due to excessive stone size(>20 mm).Conclusion PTPBD is a safe,effective,and minimally invasive treatment for CBDS with a high success rate,which is especially suitable for the patients with older age,multiple underlying diseases,inability to toler-ate surgical procedure,and without suitable endoscopic pathways,and the method is worthy of clinical promotion.

Objective To analyze the effect of percutaneous transhepatic cholangial drainage(PTCD)combined with percutaneous transhepatic papillary balloon dilation(PTPBD)in the treatment of common bile duct stone in elderly patients.Methods The clinical data of elderly patients treated with PTCD combined with PTPBD under digital subtraction angiography(DSA)for common bile duct stone were retrospectively collected,the changes in liver function,postoperative complications,and prognosis were analyzed.Results All 70 patients were successfully treated with PTCD,and other 3 patients died after PTCD operation,mainly due to severe infection combined with a variety of underlying diseases.Among the remaining 67 patients,65 cases(97.00%)were successfully treated with PTPBD,while other 2 cases(3.00%)experienced technical failure due to excessive stone size(>20 mm).Among the 70 cases after the pro-cedure,there were 5 cases with abdominal pain,2 cases with bleeding,4 cases with fever,and no serious complications occurred,such as bile duct perforation,intestinal perforation,or pancreatitis.The symptoms of 67 patients were improved from 3 to 7 days after PTCD,and the changes in leukocyte,total bilirubin,alanine aminotransferase and C-reactive protein before and after surgery were sta-tistically significant(P<0.05).Conclusion PTCD combined with PTPBD is a minimally invasive treatment method for common bile duct stone with a high success rate,safety,and effectiveness,which is especially suitable for elderly patients with multiple under-lying diseases,an inability to tolerate surgical and endoscopic treatments.It is worthy of clinical promotion and application.

Objective To investigate the clinical effect of digital subtraction angiography(DSA)-guided percutaneous transhepatic cholangial drainage(PTCD)in treatment of acute obstructive suppurative cholangitis(AOSC).Methods The relevant data of DSA-guided PTCD in treatment of AOSC patients were collected to analyze its safety and effectiveness.Results Among the 70 patients,there were 2 cases of bleeding,1 case of drainage tube blockage,and 1 case of drainage tube detachment,and no other serious surgical related complications occurred.The symptoms of 66 patients were improved from 3 to 7 d after PTCD compared with those before PTCD,and 4 patients died during hospitalization.The average daily bile drainage volume of patients was(650±130)m L,and the changes of leukocyte,total bilirubin,alanine aminotransferase and alkaline phosphatase indexes before and after surgery were statisti-cally significant(P<0.05).Conclusion DSA-guided PTCD in treatment of AOSC is a safe and effective minimally invasive method with high technical success rate,which can timely relieve obstruction,improve symptoms,reduce mortality,and create opportunities and conditions for secondary surgery or interventional therapy.

Objective:To investigate the clinical effect of percutaneous transhepatic cholangial drainage (PTCD) combined with percutaneous transhepatic papillary balloon dilatation (PTPBD) in the treatment of choledocholithiasis.Methods:The clinical data of patients treated with PTCD combined with PTPBD under digital subtraction angiography for choledocholithiasis in the Interventional Department of the Second Affiliated Hospital of Nantong University from June 2021 to May 2024 were retrospectively analyzed, and a total of 90 patients were enrolled, including 58 males and 32 females, aged (56.6±4.3) years. The changes of liver function, postoperative complications, and prognosis were analyzed.Results:Of 90 patients were successfully treated with PTCD, and 3 patients (3.3%) died after PTCD operation, mainly due to old age combined with a variety of underlying diseases. 85(97.7%) of the remaining 87 patients were successfully treated with PTPBD, while 2 cases (2.3%) experienced technical failure due to excessive stone size (>20 mm). Among the 90 cases after the procedure, there were 6 cases (6.7%) of abdominal pain, 3 cases (3.3%) of bleeding, 4 cases (4.4%) of fever, and no serious complications such as bile duct perforation, intestinal perforation or pancreatitis occurred. The symptoms of 87 patients were improved within 3 to 7 days after PTCD. The changes of leukocyte, total bilirubin, alanine aminotransferase and C reactive protein before and after surgery were statistically significant (all P<0.001). Conclusions:PTCD combined with PTPBD is a minimally invasive treatment for common bile duct stones with obvious advantages in high success rate, safety, and effectiveness, which is especially suitable for elderly patients with multiple underlying diseases, inability to tolerate surgical procedures, or no suitable endoscopic pathways.

Objective:To analyse the clinical effect of percutaneous transhepatic papillary balloon dilatation (PTPBD) combined with lithotriptic basket in the treatment of large-diameter common bile duct stone (CBDS) after percutaneous transhepatic cholangia drainage (PTCD).Methods:The clinical data of 50 patients treated with PTPBD combined with lithotriptic basket after PTCD under digital subtraction angiography (DSA) for large-diameter CBDS in the Department of Interventional Radiology, the Second Affiliated Hospital of Nantong University from October 2021 to September 2024 were retrospectively analyzed, including 38 males and 12 females, aged (57.6±3.6) years. Clinical data, including gender, age, long diameter of the stone, and surgery-related complications, were recorded. Changes in leukocyte count, total bilirubin, alanine transaminase and C-reactive protein were compared before PTCD and on the 5th postoperative day.Results:All 50 cases were successfully treated with PTCD. Significant improvements were observed in white blood cell count [(7.35±2.36)×10 9/L vs. (11.34±2.81)×10 9/L], total bilirubin [(27.58±6.24) μmol/L vs. (74.35±12.26) μmol/L], alanine transaminase [(41.25±8.65) U/L vs. (141.41±29.16) U/L] and C-reactive protein [(39.34±13.45) mg/L vs. (81.43±31.35) mg/L] before and after PTCD (all P<0.001). The time interval between PTCD and PTPBD was (14.46±1.01) d. Among the 50 patients, 48 cases (96.0%) were successfully treated with PTPBD combined with a lithotriptic basket, while 2 cases (4.0%) failed due to the basket's inability to retrieve the stones. Among the 50 patients after PTCD, 2 cases (4.0%) of abdominal pain, 2 cases (4.0%) of bleeding, and 2 cases (4.0%) of fever. Following PTPBD with lithotriptic basket stone removal, abdominal pain occurred in 3 patients (6.0%) and fever in 2 (4.0%). Conclusion:PTPBD combined with lithotriptic basket in the second stage after PTCD under DSA is a minimally invasive treatment for large-diameter CBDS with safety and effectiveness.