Objective To explore the correlation between triglyceride-glucose(TyG)index and hyperuricemia in men with normal fasting blood glucose(FPG)levels.Methods A total of 309 men with normal FPG who participated in a health examination at the Ninth Medical Center of the People's Liberation Army General Hospital in April 2024 were enrolled in this study.All the subjects were divided into the normal uric acid(NUA,n=218)group and the hyperuricemia(HUA,n=91)group according to serum uric acid(SUA)levels.Results Scr,TG,weight,SBP,DBP,BMI,ALT,AST,γ-GGT,and TyG index were higher in the HUA group than in the NUA group(P<0.05).Pearson and Spearman correlation analysis showed that SUA were positively correlated with Scr,eGFR,TG,weight,SBP,DBP,BMI,ALT,AST,γ-GGT and TyG(P<0.05),and negatively correlated with HDL-C(P<0.05).Logistic regression analysis showed that after adjusting for confounding factors,TyG index remained an important influencing factor for HUA.ROC curve analysis showed that the area under the ROC curve of TyG index predicting hyperuricemia in men with normal FPG was 0.665,with an cutoff value of 8.45.Conclusions TyG index in men with normal FPG are influencing factors for hyperuricemia,indicating that hyperuricemia has a close association with insulin resistance,and is an important component of metabolic syndrome.

Intracranial or extracranial artery stenosis is the major reason of ischemic stroke,which leads to insufficient cerebral blood flow perfusion and triggers cerebral dysfunction.The detection rate of unruptured intracranial aneurysm(UIA)combined with intracranial or extracranial artery stenosis is increasing with advances in diagnostic techniques for cerebrovascular disease.Due to the complexity of location and hemodynamic implications,there is no consensus on the treatment of UIA combined with intracranial or extracranial artery stenosis.This article summarized several types of UIA combined with intracranial or extracranial artery stenosis in terms of anatomical location,hemodynamics,and therapy strategies,aiming to provide references for clinical interventionalists.

To investigate the bone health status and potential influencing factors of bone mineral density in adult patients with hemophilia, providing a reference for improving their bone health and for the prevention, treatment, and rehabilitation intervention of osteoporosis.

Body weight abnormalities, including overweight, obesity, and underweight, have become a dual public health challenge in Chinese adults: overweight and obesity lead to a variety of chronic complications, while underweight increases the risks of malnutrition, sarcopenia, and organ dysfunction. To systematically address these issues, multidisciplinary experts in endocrinology, sports science, nutrition, and psychiatry from various regions have held multiple weight management seminars. Based on the latest epidemiological data and clinical evidence, they expanded the guideline to include assessment and intervention strategies for underweight, in addition to the core content of obesity management. This guideline outlines the etiological mechanisms, evaluation methods, and multidimensional management strategies for overweight and obesity, covering key areas such as diagnosis and assessment, medical nutrition therapy, exercise prescription, pharmacological intervention, and psychological support. It is intended to provide a scientific and standardized approach to weight management across the adult population, aiming to curb the rising prevalence of obesity, mitigate complications associated with abnormal body weight, and improve nutritional status and overall quality of life.

Objective To explore the correlation between triglyceride-glucose(TyG)index and hyperuricemia in men with normal fasting blood glucose(FPG)levels.Methods A total of 309 men with normal FPG who participated in a health examination at the Ninth Medical Center of the People's Liberation Army General Hospital in April 2024 were enrolled in this study.All the subjects were divided into the normal uric acid(NUA,n=218)group and the hyperuricemia(HUA,n=91)group according to serum uric acid(SUA)levels.Results Scr,TG,weight,SBP,DBP,BMI,ALT,AST,γ-GGT,and TyG index were higher in the HUA group than in the NUA group(P<0.05).Pearson and Spearman correlation analysis showed that SUA were positively correlated with Scr,eGFR,TG,weight,SBP,DBP,BMI,ALT,AST,γ-GGT and TyG(P<0.05),and negatively correlated with HDL-C(P<0.05).Logistic regression analysis showed that after adjusting for confounding factors,TyG index remained an important influencing factor for HUA.ROC curve analysis showed that the area under the ROC curve of TyG index predicting hyperuricemia in men with normal FPG was 0.665,with an cutoff value of 8.45.Conclusions TyG index in men with normal FPG are influencing factors for hyperuricemia,indicating that hyperuricemia has a close association with insulin resistance,and is an important component of metabolic syndrome.

Intracranial or extracranial artery stenosis is the major reason of ischemic stroke,which leads to insufficient cerebral blood flow perfusion and triggers cerebral dysfunction.The detection rate of unruptured intracranial aneurysm(UIA)combined with intracranial or extracranial artery stenosis is increasing with advances in diagnostic techniques for cerebrovascular disease.Due to the complexity of location and hemodynamic implications,there is no consensus on the treatment of UIA combined with intracranial or extracranial artery stenosis.This article summarized several types of UIA combined with intracranial or extracranial artery stenosis in terms of anatomical location,hemodynamics,and therapy strategies,aiming to provide references for clinical interventionalists.

[Objective]To investigate the clinical characteristics and efficacy of Chief KONG Yaoqi's scalp acupuncture triotherapy in the treatment of tic disorder.[Methods]This study analyzed and summarized the theoretical foundation and operational techniques of Chief KONG's scalp acupuncture triotherapy through collecting and analyzing the typical cases and relevant literature.Additionally,a supporting case is provided.[Results]Tic disorder is a common neuropsychiatric disease.Chief KONG believes that the location of tic disorder is in the brain and heart,emphasizing treatment based on the spirit.Scalp acupuncture can stimulate specific regions of the head,thereby enhancing neurological function.Body acupuncture is used to treat the cause and mechanism with tonification and purgation,while acupoint application is used to enhance the body's resistance and nourish the primordial energy.The patient in this case was caused by wind movement due to deficiency,Chief KONG used scalp acupuncture to calm the mind and spirit to stop the tics,body acupuncture to suppress wind and stop convulsions to control the movements,indirect moxibustion and acupoint application to tonify the kidney and spleen.The therapeutic effect was definite.[Conclusion]Chief KONG's combined therapy of scalp acupuncture emphasizes treating children's tic disorder based on the spirit and focuses on tonifying the liver,spleen and kidney.His clinical experience is worthy of promotion and application in clinical practice.

[Objective]To investigate the clinical characteristics and efficacy of Chief KONG Yaoqi's scalp acupuncture triotherapy in the treatment of tic disorder.[Methods]This study analyzed and summarized the theoretical foundation and operational techniques of Chief KONG's scalp acupuncture triotherapy through collecting and analyzing the typical cases and relevant literature.Additionally,a supporting case is provided.[Results]Tic disorder is a common neuropsychiatric disease.Chief KONG believes that the location of tic disorder is in the brain and heart,emphasizing treatment based on the spirit.Scalp acupuncture can stimulate specific regions of the head,thereby enhancing neurological function.Body acupuncture is used to treat the cause and mechanism with tonification and purgation,while acupoint application is used to enhance the body's resistance and nourish the primordial energy.The patient in this case was caused by wind movement due to deficiency,Chief KONG used scalp acupuncture to calm the mind and spirit to stop the tics,body acupuncture to suppress wind and stop convulsions to control the movements,indirect moxibustion and acupoint application to tonify the kidney and spleen.The therapeutic effect was definite.[Conclusion]Chief KONG's combined therapy of scalp acupuncture emphasizes treating children's tic disorder based on the spirit and focuses on tonifying the liver,spleen and kidney.His clinical experience is worthy of promotion and application in clinical practice.

Body weight abnormalities, including overweight, obesity, and underweight, have become a dual public health challenge in Chinese adults: overweight and obesity lead to a variety of chronic complications, while underweight increases the risks of malnutrition, sarcopenia, and organ dysfunction. To systematically address these issues, multidisciplinary experts in endocrinology, sports science, nutrition, and psychiatry from various regions have held multiple weight management seminars. Based on the latest epidemiological data and clinical evidence, they expanded the guideline to include assessment and intervention strategies for underweight, in addition to the core content of obesity management. This guideline outlines the etiological mechanisms, evaluation methods, and multidimensional management strategies for overweight and obesity, covering key areas such as diagnosis and assessment, medical nutrition therapy, exercise prescription, pharmacological intervention, and psychological support. It is intended to provide a scientific and standardized approach to weight management across the adult population, aiming to curb the rising prevalence of obesity, mitigate complications associated with abnormal body weight, and improve nutritional status and overall quality of life.

Objective:To provide warning information for early renal injury in pilots by investigating the relationship between serum cystatin C (Cys-C) level and renal blood flow parameters in healthy pilots.Methods:A total of 347 military pilots who underwent annual physical examination in the Air Service Department of the 960th Hospital of Joint Logistics Support Force from July of 2019 to December of 2021 were selected as the pilot group, and 347 healthy subjects who were in same age span and examined at same period were selected as the control group. Color Doppler flow imaging was used to qualitatively analyze renal artery blood flow parameters, including the peak systolic velocity (PSV), end-diastolic blood flow velocity (EDV) and resistance index (RI) of the main renal artery, segmental artery and interlobar arteries. The serum urea nitrogen, serum creatinine and uric acid of subjects were measured. Both pilot group and the control group were divided into 21-30 years old, 31-40 years old and 41-50 years old groups. According to the median level of serum Cys-C, the pilots were divided into high Cys-C group and low Cys-C group. The Cys-C level and renal blood flow parameters of each group were compared, and the correlation between Cys-C level and renal blood flow parameters of pilots was analyzed.Results:There were no significant differences on serum Cys-C level between the pilot group and the control group at all ages (all P>0.05). There was a significant difference on Cys-C levels among the pilots of different ages ( H=8.24, P=0.045). There was no significant difference in Cys-C levels among control groups at different ages ( P>0.05). The levels of endogenous creatinine clearance and uric acid in the high Cys-C group were higher than those in the low Cys-C group, and the differences were significant ( Z=-4.17, -2.98, P<0.001, =0.003). The EDV of main renal artery in high Cys-C group was lower than that in low Cys-C group, and the difference was significant ( t=4.82, P=0.021). The EDV of interlobar arteries in high Cys-C group was lower than that in low Cys-C group, and the difference was significant ( Z=-5.48, P=0.030). Correlation analysis showed that the Cys-C level of pilots was positively correlated with age, flying hours and uric acid level ( r=0.381, 0.165, 0.359, P=0.001, 0.002, 0.003). Cys-C level was negatively correlated with EDV of main renal artery and interlobar arteries ( r=-0.306, -0.321, P=0.048, 0.024), and positively correlated with RI of main renal artery ( r=0.417, P=0.029). Conclusions:The serum Cys-C of pilots could reflect certain basic data of renal function and is hopeful to provide warning for early renal injury due it correlated to the EDV of main renal artery and interlobar arteries and the RI of main renal artery.