1.Research on motor imagery recognition based on feature fusion and transfer adaptive boosting.
Yuxin ZHANG ; Chenrui ZHANG ; Shihao SUN ; Guizhi XU
Journal of Biomedical Engineering 2025;42(1):9-16
This paper proposes a motor imagery recognition algorithm based on feature fusion and transfer adaptive boosting (TrAdaboost) to address the issue of low accuracy in motor imagery (MI) recognition across subjects, thereby increasing the reliability of MI-based brain-computer interfaces (BCI) for cross-individual use. Using the autoregressive model, power spectral density and discrete wavelet transform, time-frequency domain features of MI can be obtained, while the filter bank common spatial pattern is used to extract spatial domain features, and multi-scale dispersion entropy is employed to extract nonlinear features. The IV-2a dataset from the 4 th International BCI Competition was used for the binary classification task, with the pattern recognition model constructed by combining the improved TrAdaboost integrated learning algorithm with support vector machine (SVM), k nearest neighbor (KNN), and mind evolutionary algorithm-based back propagation (MEA-BP) neural network. The results show that the SVM-based TrAdaboost integrated learning algorithm has the best performance when 30% of the target domain instance data is migrated, with an average classification accuracy of 86.17%, a Kappa value of 0.723 3, and an AUC value of 0.849 8. These results suggest that the algorithm can be used to recognize MI signals across individuals, providing a new way to improve the generalization capability of BCI recognition models.
Brain-Computer Interfaces
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Humans
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Support Vector Machine
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Algorithms
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Neural Networks, Computer
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Imagination/physiology*
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Pattern Recognition, Automated/methods*
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Electroencephalography
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Wavelet Analysis
2.Evaluation method and system for aging effects of autonomic nervous system based on cross-wavelet transform cardiopulmonary coupling.
Juntong LYU ; Yining WANG ; Wenbin SHI ; Pengyan TAO ; Jianhong YE
Journal of Biomedical Engineering 2025;42(4):748-756
Heart rate variability time and frequency indices are widely used in functional assessment for autonomic nervous system (ANS). However, this method merely analyzes the effect of cardiac dynamics, overlooking the effect of cardio-pulmonary interplays. Given this, the present study proposes a novel cardiopulmonary coupling (CPC) algorithm based on cross-wavelet transform to quantify cardio-pulmonary interactions, and establish an assessment system for ANS aging effects using wearable electrocardiogram (ECG) and respiratory monitoring devices. To validate the superiority of the proposed method under nonstationary and low signal-to-noise ratio conditions, simulations were first conducted to demonstrate the performance strength of the proposed method to the traditional one. Next, the proposed CPC algorithm was applied to analyze cardiac and respiratory data from both elderly and young populations, revealing that young populations exhibited significantly stronger couplings in the high-frequency band compared with their elderly counterparts. Finally, a CPC assessment system was constructed by integrating wearable devices, and additional recordings from both elderly and young populations were collected by using the system, completing the validation and application of the aging effect assessment algorithm and the wearable system. In conclusion, this study may offers methodological and system support for assessing the aging effects on the ANS.
Humans
;
Autonomic Nervous System/physiology*
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Algorithms
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Aging/physiology*
;
Electrocardiography/methods*
;
Heart Rate/physiology*
;
Wavelet Analysis
;
Aged
;
Signal Processing, Computer-Assisted
;
Wearable Electronic Devices
3.AQMFB-DWT: A Preprocessing Technique for Removing Blink Artifacts Before Extracting Pain-evoked Potential EEG.
Wenjia GAO ; Dan LIU ; Qisong WANG ; Yongping ZHAO ; Jinwei SUN
Neuroscience Bulletin 2025;41(12):2285-2295
The pain-evoked potential electroencephalogram (EEG) is an effective electrophysiological indicator for pain assessment, yet its extraction is challenging due to interference from background activity and involuntary blinks. Although existing blink artifact-removal methods show efficacy, they face limitations such as the need for reference signals, neglect of individual differences, and reliance on user input, hindering their practical application in clinical pain assessments. In this paper, we propose a novel framework applying adaptive quadrature mirror filter banks (AQMFB) with discrete wavelet transform (DWT) to remove blink artifacts in pain EEG. Unlike traditional DWT methods that apply fixed wavelets across subjects, our method adapts wavelet construction based on the characteristics of EEG. Experimental results demonstrate that AQMFB-DWT outperforms four leading methods in removing blink artifacts with minimal distortion of pain information, all within an acceptable processing time. This technique is a valuable preprocessing step for enhancing the extraction of pain-evoked potentials.
Humans
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Artifacts
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Blinking/physiology*
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Electroencephalography/methods*
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Pain/diagnosis*
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Male
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Wavelet Analysis
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Adult
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Female
;
Evoked Potentials/physiology*
;
Young Adult
;
Brain/physiopathology*
;
Pain Measurement/methods*
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Signal Processing, Computer-Assisted
4.Automatic sleep staging algorithm for stochastic depth residual networks based on transfer learning.
Yunzhi TIAN ; Qiang ZHOU ; Wan LI
Journal of Biomedical Engineering 2023;40(2):286-294
The existing automatic sleep staging algorithms have the problems of too many model parameters and long training time, which in turn results in poor sleep staging efficiency. Using a single channel electroencephalogram (EEG) signal, this paper proposed an automatic sleep staging algorithm for stochastic depth residual networks based on transfer learning (TL-SDResNet). Firstly, a total of 30 single-channel (Fpz-Cz) EEG signals from 16 individuals were selected, and after preserving the effective sleep segments, the raw EEG signals were pre-processed using Butterworth filter and continuous wavelet transform to obtain two-dimensional images containing its time-frequency joint features as the input data for the staging model. Then, a ResNet50 pre-trained model trained on a publicly available dataset, the sleep database extension stored in European data format (Sleep-EDFx) was constructed, using a stochastic depth strategy and modifying the output layer to optimize the model structure. Finally, transfer learning was applied to the human sleep process throughout the night. The algorithm in this paper achieved a model staging accuracy of 87.95% after conducting several experiments. Experiments show that TL-SDResNet50 can accomplish fast training of a small amount of EEG data, and the overall effect is better than other staging algorithms and classical algorithms in recent years, which has certain practical value.
Humans
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Sleep Stages
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Algorithms
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Sleep
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Wavelet Analysis
;
Electroencephalography/methods*
;
Machine Learning
5.Epilepsy detection and analysis method for specific patient based on data augmentation and deep learning.
Yong YANG ; Xiaolin QIN ; Xiaoguang LIN ; Han WEN ; Yuncong PENG
Journal of Biomedical Engineering 2022;39(2):293-300
In recent years, epileptic seizure detection based on electroencephalogram (EEG) has attracted the widespread attention of the academic. However, it is difficult to collect data from epileptic seizure, and it is easy to cause over fitting phenomenon under the condition of few training data. In order to solve this problem, this paper took the CHB-MIT epilepsy EEG dataset from Boston Children's Hospital as the research object, and applied wavelet transform for data augmentation by setting different wavelet transform scale factors. In addition, by combining deep learning, ensemble learning, transfer learning and other methods, an epilepsy detection method with high accuracy for specific epilepsy patients was proposed under the condition of insufficient learning samples. In test, the wavelet transform scale factors 2, 4 and 8 were set for experimental comparison and verification. When the wavelet scale factor was 8, the average accuracy, average sensitivity and average specificity was 95.47%, 93.89% and 96.48%, respectively. Through comparative experiments with recent relevant literatures, the advantages of the proposed method were verified. Our results might provide reference for the clinical application of epilepsy detection.
Algorithms
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Child
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Deep Learning
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Electroencephalography
;
Epilepsy/diagnosis*
;
Humans
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Seizures/diagnosis*
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Signal Processing, Computer-Assisted
;
Wavelet Analysis
6.An Adaptive Method for Detecting and Removing EEG Noise.
Si-Nian YUAN ; Ruo-Wei LI ; Zi-Fu ZHU ; Sheng-Cai MA ; Hang-Duo NIU ; Ji-Lun YE ; Xu ZHANG
Chinese Journal of Medical Instrumentation 2022;46(3):248-253
To solve the problem of real-time detection and removal of EEG signal noise in anesthesia depth monitoring, we proposed an adaptive EEG signal noise detection and removal method. This method uses discrete wavelet transform to extract the low-frequency energy and high-frequency energy of a segment of EEG signals, and sets two sets of thresholds for the low-frequency band and high-frequency band of the EEG signal. These two sets of thresholds can be updated adaptively according to the energy situation of the most recent EEG signal. Finally, we judge the level of signal interference according to the range of low-frequency energy and high-frequency energy, and perform corresponding denoising processing. The results show that the method can more accurately detect and remove the noise interference in the EEG signal, and improve the stability of the calculated characteristic parameters.
Algorithms
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Electroencephalography
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Signal Processing, Computer-Assisted
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Signal-To-Noise Ratio
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Wavelet Analysis
7.Bowel Sounds Detection Method and Experiment Based on Multi-feature Combination.
Siqi LIU ; Xianrong WAN ; Deqiang XIE ; Congqing JIANG ; Xianghai REN
Chinese Journal of Medical Instrumentation 2022;46(5):473-480
Bowel sounds is an important indicator to monitor and reflect intestinal motor function, and traditional manual auscultation requires high professional knowledge and rich clinical experience of doctors. In addition, long-time auscultation is time-consuming and laborious, which may lead to misjudgment caused by subjective error. To solve the problem, firstly, the wavelet transform is used to preprocess the bowel sounds signal for noise reduction and enhancement. Secondly, three typical features of intestinal sound were extracted. According to the combination of these features, a three-stage decision was designed to carry out multi-parameter and multi-feature joint threshold detection. This algorithm realized the detection of bowel sound signal and the location of its start and end points, making it possible that the complete bowel sound signal was extracted effectively. In this study, a large number of clinical data and label of bowel sounds were collected, and a new effective evaluation method was proposed to verify the proposed method. The accuracy rate is 83.51%. Results of this study will provide systematic support and theoretical guarantee for the diagnosis of intestinal diseases and the monitoring of postoperative intestinal function recovery of patients.
Algorithms
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Auscultation
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Humans
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Intestines
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Signal Processing, Computer-Assisted
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Wavelet Analysis
8.Research on automatic removal of ocular artifacts from single channel electroencephalogram signals based on wavelet transform and ensemble empirical mode decomposition.
Rui ZHANG ; Jiajun LIU ; Mingming CHEN ; Lipeng ZHANG ; Yuxia HU
Journal of Biomedical Engineering 2021;38(3):473-482
The brain-computer interface (BCI) systems used in practical applications require as few electroencephalogram (EEG) acquisition channels as possible. However, when it is reduced to one channel, it is difficult to remove the electrooculogram (EOG) artifacts. Therefore, this paper proposed an EOG artifact removal algorithm based on wavelet transform and ensemble empirical mode decomposition. Firstly, the single channel EEG signal is subjected to wavelet transform, and the wavelet components which involve EOG artifact are decomposed by ensemble empirical mode decomposition. Then the predefined autocorrelation coefficient threshold is used to automatically select and remove the intrinsic modal functions which mainly composed of EOG components. And finally the 'clean' EEG signal is reconstructed. The comparative experiments on the simulation data and the real data show that the algorithm proposed in this paper solves the problem of automatic removal of EOG artifacts in single-channel EEG signals. It can effectively remove the EOG artifacts when causes less EEG distortion and has less algorithm complexity at the same time. It helps to promote the BCI technology out of the laboratory and toward commercial application.
Algorithms
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Artifacts
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Computer Simulation
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Electroencephalography
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Signal Processing, Computer-Assisted
;
Wavelet Analysis
9.A heart rate detection method for wearable electrocardiogram with the presence of motion interference.
Jialing XIE ; Yushun GONG ; Liang WEI ; Juan WANG ; Weiming LI ; Yongqin LI
Journal of Biomedical Engineering 2021;38(4):764-773
The dynamic electrocardiogram (ECG) collected by wearable devices is often corrupted by motion interference due to human activities. The frequency of the interference and the frequency of the ECG signal overlap with each other, which distorts and deforms the ECG signal, and then affects the accuracy of heart rate detection. In this paper, a heart rate detection method that using coarse graining technique was proposed. First, the ECG signal was preprocessed to remove the baseline drift and the high-frequency interference. Second, the motion-related high amplitude interference exceeding the preset threshold was suppressed by signal compression method. Third, the signal was coarse-grained by adaptive peak dilation and waveform reconstruction. Heart rate was calculated based on the frequency spectrum obtained from fast Fourier transformation. The performance of the method was compared with a wavelet transform based QRS feature extraction algorithm using ECG collected from 30 volunteers at rest and in different motion states. The results showed that the correlation coefficient between the calculated heart rate and the standard heart rate was 0.999, which was higher than the result of the wavelet transform method (
Electrocardiography
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Heart Rate
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Humans
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Signal Processing, Computer-Assisted
;
Wavelet Analysis
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Wearable Electronic Devices
10.An anesthesia depth computing method study based on wavelet transform and artificial neural network.
Sinian YUAN ; Jilun YE ; Xu ZHANG ; Jingjing ZHOU ; Xue TAN ; Ruowei LI ; Zhuqiang DENG ; Yaomao DING
Journal of Biomedical Engineering 2021;38(5):838-847
General anesthesia is an essential part of surgery to ensure the safety of patients. Electroencephalogram (EEG) has been widely used in anesthesia depth monitoring for abundant information and the ability of reflecting the brain activity. The paper proposes a method which combines wavelet transform and artificial neural network (ANN) to assess the depth of anesthesia. Discrete wavelet transform was used to decompose the EEG signal, and the approximation coefficients and detail coefficients were used to calculate the 9 characteristic parameters. Kruskal-Wallis statistical test was made to these characteristic parameters, and the test showed that the parameters were statistically significant for the differences of the four levels of anesthesia: awake, light anesthesia, moderate anesthesia and deep anesthesia (
Algorithms
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Anesthesia, General
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Electroencephalography
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Humans
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Neural Networks, Computer
;
Wavelet Analysis

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