1.Automatic sleep staging algorithm for stochastic depth residual networks based on transfer learning.
Yunzhi TIAN ; Qiang ZHOU ; Wan LI
Journal of Biomedical Engineering 2023;40(2):286-294
The existing automatic sleep staging algorithms have the problems of too many model parameters and long training time, which in turn results in poor sleep staging efficiency. Using a single channel electroencephalogram (EEG) signal, this paper proposed an automatic sleep staging algorithm for stochastic depth residual networks based on transfer learning (TL-SDResNet). Firstly, a total of 30 single-channel (Fpz-Cz) EEG signals from 16 individuals were selected, and after preserving the effective sleep segments, the raw EEG signals were pre-processed using Butterworth filter and continuous wavelet transform to obtain two-dimensional images containing its time-frequency joint features as the input data for the staging model. Then, a ResNet50 pre-trained model trained on a publicly available dataset, the sleep database extension stored in European data format (Sleep-EDFx) was constructed, using a stochastic depth strategy and modifying the output layer to optimize the model structure. Finally, transfer learning was applied to the human sleep process throughout the night. The algorithm in this paper achieved a model staging accuracy of 87.95% after conducting several experiments. Experiments show that TL-SDResNet50 can accomplish fast training of a small amount of EEG data, and the overall effect is better than other staging algorithms and classical algorithms in recent years, which has certain practical value.
Humans
;
Sleep Stages
;
Algorithms
;
Sleep
;
Wavelet Analysis
;
Electroencephalography/methods*
;
Machine Learning
2.Bowel Sounds Detection Method and Experiment Based on Multi-feature Combination.
Siqi LIU ; Xianrong WAN ; Deqiang XIE ; Congqing JIANG ; Xianghai REN
Chinese Journal of Medical Instrumentation 2022;46(5):473-480
Bowel sounds is an important indicator to monitor and reflect intestinal motor function, and traditional manual auscultation requires high professional knowledge and rich clinical experience of doctors. In addition, long-time auscultation is time-consuming and laborious, which may lead to misjudgment caused by subjective error. To solve the problem, firstly, the wavelet transform is used to preprocess the bowel sounds signal for noise reduction and enhancement. Secondly, three typical features of intestinal sound were extracted. According to the combination of these features, a three-stage decision was designed to carry out multi-parameter and multi-feature joint threshold detection. This algorithm realized the detection of bowel sound signal and the location of its start and end points, making it possible that the complete bowel sound signal was extracted effectively. In this study, a large number of clinical data and label of bowel sounds were collected, and a new effective evaluation method was proposed to verify the proposed method. The accuracy rate is 83.51%. Results of this study will provide systematic support and theoretical guarantee for the diagnosis of intestinal diseases and the monitoring of postoperative intestinal function recovery of patients.
Algorithms
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Auscultation
;
Humans
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Intestines
;
Signal Processing, Computer-Assisted
;
Wavelet Analysis
3.An Adaptive Method for Detecting and Removing EEG Noise.
Si-Nian YUAN ; Ruo-Wei LI ; Zi-Fu ZHU ; Sheng-Cai MA ; Hang-Duo NIU ; Ji-Lun YE ; Xu ZHANG
Chinese Journal of Medical Instrumentation 2022;46(3):248-253
To solve the problem of real-time detection and removal of EEG signal noise in anesthesia depth monitoring, we proposed an adaptive EEG signal noise detection and removal method. This method uses discrete wavelet transform to extract the low-frequency energy and high-frequency energy of a segment of EEG signals, and sets two sets of thresholds for the low-frequency band and high-frequency band of the EEG signal. These two sets of thresholds can be updated adaptively according to the energy situation of the most recent EEG signal. Finally, we judge the level of signal interference according to the range of low-frequency energy and high-frequency energy, and perform corresponding denoising processing. The results show that the method can more accurately detect and remove the noise interference in the EEG signal, and improve the stability of the calculated characteristic parameters.
Algorithms
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Electroencephalography
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Signal Processing, Computer-Assisted
;
Signal-To-Noise Ratio
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Wavelet Analysis
4.Epilepsy detection and analysis method for specific patient based on data augmentation and deep learning.
Yong YANG ; Xiaolin QIN ; Xiaoguang LIN ; Han WEN ; Yuncong PENG
Journal of Biomedical Engineering 2022;39(2):293-300
In recent years, epileptic seizure detection based on electroencephalogram (EEG) has attracted the widespread attention of the academic. However, it is difficult to collect data from epileptic seizure, and it is easy to cause over fitting phenomenon under the condition of few training data. In order to solve this problem, this paper took the CHB-MIT epilepsy EEG dataset from Boston Children's Hospital as the research object, and applied wavelet transform for data augmentation by setting different wavelet transform scale factors. In addition, by combining deep learning, ensemble learning, transfer learning and other methods, an epilepsy detection method with high accuracy for specific epilepsy patients was proposed under the condition of insufficient learning samples. In test, the wavelet transform scale factors 2, 4 and 8 were set for experimental comparison and verification. When the wavelet scale factor was 8, the average accuracy, average sensitivity and average specificity was 95.47%, 93.89% and 96.48%, respectively. Through comparative experiments with recent relevant literatures, the advantages of the proposed method were verified. Our results might provide reference for the clinical application of epilepsy detection.
Algorithms
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Child
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Deep Learning
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Electroencephalography
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Epilepsy/diagnosis*
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Humans
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Seizures/diagnosis*
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Signal Processing, Computer-Assisted
;
Wavelet Analysis
5.An anesthesia depth computing method study based on wavelet transform and artificial neural network.
Sinian YUAN ; Jilun YE ; Xu ZHANG ; Jingjing ZHOU ; Xue TAN ; Ruowei LI ; Zhuqiang DENG ; Yaomao DING
Journal of Biomedical Engineering 2021;38(5):838-847
General anesthesia is an essential part of surgery to ensure the safety of patients. Electroencephalogram (EEG) has been widely used in anesthesia depth monitoring for abundant information and the ability of reflecting the brain activity. The paper proposes a method which combines wavelet transform and artificial neural network (ANN) to assess the depth of anesthesia. Discrete wavelet transform was used to decompose the EEG signal, and the approximation coefficients and detail coefficients were used to calculate the 9 characteristic parameters. Kruskal-Wallis statistical test was made to these characteristic parameters, and the test showed that the parameters were statistically significant for the differences of the four levels of anesthesia: awake, light anesthesia, moderate anesthesia and deep anesthesia (
Algorithms
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Anesthesia, General
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Electroencephalography
;
Humans
;
Neural Networks, Computer
;
Wavelet Analysis
6.Automatic epileptic seizure detection algorithm based on dual density dual tree complex wavelet transform.
Tongzhou KANG ; Rundong ZUO ; Lanfeng ZHONG ; Wenjing CHEN ; Heng ZHANG ; Hongxiu LIU ; Dakun LAI
Journal of Biomedical Engineering 2021;38(6):1035-1042
It is very important for epilepsy treatment to distinguish epileptic seizure and non-seizure. In this study, an automatic seizure detection algorithm based on dual density dual tree complex wavelet transform (DD-DT CWT) for intracranial electroencephalogram (iEEG) was proposed. The experimental data were collected from 15 719 competition data set up by the National Institutes of Health (NINDS) in Kaggle. The processed database consisted of 55 023 seizure epochs and 501 990 non-seizure epochs. Each epoch was 1 second long and contained 174 sampling points. Firstly, the signal was resampled. Then, DD-DT CWT was used for EEG signal processing. Four kinds of features include wavelet entropy, variance, energy and mean value were extracted from the signal. Finally, these features were sent to least squares-support vector machine (LS-SVM) for learning and classification. The appropriate decomposition level was selected by comparing the experimental results under different wavelet decomposition levels. The experimental results showed that the features selected in this paper were different between seizure and non-seizure. Among the eight patients, the average accuracy of three-level decomposition classification was 91.98%, the sensitivity was 90.15%, and the specificity was 93.81%. The work of this paper shows that our algorithm has excellent performance in the two classification of EEG signals of epileptic patients, and can detect the seizure period automatically and efficiently.
Algorithms
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Electroencephalography
;
Epilepsy/diagnosis*
;
Humans
;
Seizures/diagnosis*
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Signal Processing, Computer-Assisted
;
Support Vector Machine
;
Wavelet Analysis
7.Application of Improved Wavelet Threshold in Denoising of ECG Signals.
Xue TAN ; Jilun YE ; Xu ZHANG ; Chenyang LI ; Jingjing ZHOU ; Kejian DOU
Chinese Journal of Medical Instrumentation 2021;45(1):1-5
The ECG signal is susceptible to interference from the external environment during the acquisition process, affecting the analysis and processing of the ECG signal. After the traditional soft-hard threshold function is processed, there is a defect that the signal quality is not high and the continuity at the threshold is poor. An improved threshold function wavelet denoising is proposed, which has better regulation and continuity, and effectively solves the shortcomings of traditional soft and hard threshold functions. The Matlab simulation is carried out through a large amount of data, and various processing methods are compared. The results show that the improved threshold function can improve the denoising effect and is superior to the traditional soft and hard threshold denoising.
Algorithms
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Computer Simulation
;
Electrocardiography
;
Signal Processing, Computer-Assisted
;
Wavelet Analysis
8.Research on automatic removal of ocular artifacts from single channel electroencephalogram signals based on wavelet transform and ensemble empirical mode decomposition.
Rui ZHANG ; Jiajun LIU ; Mingming CHEN ; Lipeng ZHANG ; Yuxia HU
Journal of Biomedical Engineering 2021;38(3):473-482
The brain-computer interface (BCI) systems used in practical applications require as few electroencephalogram (EEG) acquisition channels as possible. However, when it is reduced to one channel, it is difficult to remove the electrooculogram (EOG) artifacts. Therefore, this paper proposed an EOG artifact removal algorithm based on wavelet transform and ensemble empirical mode decomposition. Firstly, the single channel EEG signal is subjected to wavelet transform, and the wavelet components which involve EOG artifact are decomposed by ensemble empirical mode decomposition. Then the predefined autocorrelation coefficient threshold is used to automatically select and remove the intrinsic modal functions which mainly composed of EOG components. And finally the 'clean' EEG signal is reconstructed. The comparative experiments on the simulation data and the real data show that the algorithm proposed in this paper solves the problem of automatic removal of EOG artifacts in single-channel EEG signals. It can effectively remove the EOG artifacts when causes less EEG distortion and has less algorithm complexity at the same time. It helps to promote the BCI technology out of the laboratory and toward commercial application.
Algorithms
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Artifacts
;
Computer Simulation
;
Electroencephalography
;
Signal Processing, Computer-Assisted
;
Wavelet Analysis
9.A heart rate detection method for wearable electrocardiogram with the presence of motion interference.
Jialing XIE ; Yushun GONG ; Liang WEI ; Juan WANG ; Weiming LI ; Yongqin LI
Journal of Biomedical Engineering 2021;38(4):764-773
The dynamic electrocardiogram (ECG) collected by wearable devices is often corrupted by motion interference due to human activities. The frequency of the interference and the frequency of the ECG signal overlap with each other, which distorts and deforms the ECG signal, and then affects the accuracy of heart rate detection. In this paper, a heart rate detection method that using coarse graining technique was proposed. First, the ECG signal was preprocessed to remove the baseline drift and the high-frequency interference. Second, the motion-related high amplitude interference exceeding the preset threshold was suppressed by signal compression method. Third, the signal was coarse-grained by adaptive peak dilation and waveform reconstruction. Heart rate was calculated based on the frequency spectrum obtained from fast Fourier transformation. The performance of the method was compared with a wavelet transform based QRS feature extraction algorithm using ECG collected from 30 volunteers at rest and in different motion states. The results showed that the correlation coefficient between the calculated heart rate and the standard heart rate was 0.999, which was higher than the result of the wavelet transform method (
Electrocardiography
;
Heart Rate
;
Humans
;
Signal Processing, Computer-Assisted
;
Wavelet Analysis
;
Wearable Electronic Devices
10.Research on the detection algorithm of electrocardiogram characteristic wave based on energy segmentation and stationary wavelet transform.
Jinzhen LIU ; Lifei SUN ; Hui XIONG ; Meiling LIANG
Journal of Biomedical Engineering 2021;38(6):1181-1192
The detection of electrocardiogram (ECG) characteristic wave is the basis of cardiovascular disease analysis and heart rate variability analysis. In order to solve the problems of low detection accuracy and poor real-time performance of ECG signal in the state of motion, this paper proposes a detection algorithm based on segmentation energy and stationary wavelet transform (SWT). Firstly, the energy of ECG signal is calculated by segmenting, and the energy candidate peak is obtained after moving average to detect QRS complex. Secondly, the QRS amplitude is set to zero and the fifth component of SWT is used to locate P wave and T wave. The experimental results show that compared with other algorithms, the algorithm in this paper has high accuracy in detecting QRS complex in different motion states. It only takes 0.22 s to detect QSR complex of a 30-minute ECG record, and the real-time performance is improved obviously. On the basis of QRS complex detection, the accuracy of P wave and T wave detection is higher than 95%. The results show that this method can improve the efficiency of ECG signal detection, and provide a new method for real-time ECG signal classification and cardiovascular disease diagnosis.
Algorithms
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Arrhythmias, Cardiac
;
Electrocardiography
;
Heart Rate
;
Humans
;
Signal Processing, Computer-Assisted
;
Wavelet Analysis

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