1.Effects of Fuzi Lizhong Oral liquid on immune function and intestinal health of chicks
Qiongyi ZHANG ; Chanchan CUI ; Shijia ZHANG ; Xiao WANG ; Xicui DU ; Yongzhan BAO ; Wanyu SHI
Chinese Journal of Veterinary Science 2025;45(4):818-824
In order to investigate the effects of Fuzi Lizhong Oral liquid on immune function and in-testinal health of chicks,185 1-day-old healthy chicks were randomly divided into 4 groups.The blank control group(CG group)was given normal tap water;the high,medium and low dose groups(FZH group,FZM group and FZL group)were given tap water containing 5.00,2.50 and 1.25 g/L of Fuzi Lizhong Oral liquid,respectively.Starting from the first day of age,the drug was administered continuously for 5 d,and the blood was collected from the subwing vein on the sixth day of the test.The results showed that compared with CG group,thymus index in FZH group was significantly increased(P<0.05).Compared with CG group,serum IgM,IgG and sIgA in FZH group were significantly increased(P<0.05),and serum IgG and sIgA in FZM group were signifi-cantly increased(P<0.05).Compared with CG group,the relative expression of Occludin and Claudin-1 mRNA in FZH group was significantly increased(P<0.05),and the relative expression of ZO-1 mRNA in FZM and FZH groups was significantly increased(P<0.05).Compared with CG group,Shannon index of FZH group was significantly increased(P<0.05),Simpson index of FZH group was significantly decreased(P<0.05),and many beneficial bacteria such as Strepto-coccus spinosus,Eubacillus spinosus and Lactobacillus spinosus played a synergistic role.The results showed that adding 5.00 g/L Fuzi Lizhong Oral liquid in drinking water could improve the immunity of chicks,maintain the intestinal barrier function of chicks,increase the intestinal flora richness and promote the intestinal health of chicks.
2.Effects of Shenling Baizhu Oral Liquid on intestinal barrier and intestinal flora of broilers
Chanchan CUI ; Shijia ZHANG ; Qiongyi ZHANG ; Xiao WANG ; Xicui DU ; Wanyu SHI ; Yongzhan BAO ; Fuxing CHEN
Chinese Journal of Veterinary Science 2025;45(5):1045-1052
A total of 300 1-day-old broilers were randomly divided into 5 groups with 5 replicates per group and 12 broilers per replicate.The control group was given free drinking water(CG),the astragalus polysaccharide control group(HPS)received 0.8 mL/L of astragalus polysaccharide o-ral liquid in drinking water,and the experimental groups(SBL,SBM,SBH)received 1.5,3.0,4.5 mL/,of Shenling Baizhu Oral Liquid in drinking water.The results showed as follows:com-pared to the CG group,SIgA content in HPS group,group SBM and group SBH was significantly increased(P<0.05),IL-6 and IL-1β contents were significantly decreased(P<0.05),Occludin,Mucin-2 and Bcl-2 contents were significantly increased(P<0.05).The results of 16S rRNA test showed that the specific OUT number in groups HPS and SBM was significantly higher than that in group CG(P<0.05),α diversity analysis showed that compared with group CG,Chao1 index and Simpson index of group HPS,group SBM and group SBH were significantly increased,and βdiversity analysis showed that there were significant differences in species composition between test group and blank control group(P<0.05).The relative abundance analysis at the phylum level showed that the relative abundance of Firmicutes and Bacteroides in groups SBM and SBH was significantly higher than that in group CG(P<0.05).The above results showed that Shenling Baizhu Oral Liquid could improve the intestinal health and enhance the resistance of broilers.
3.Effects of Fuzi Lizhong Oral liquid on immune function and intestinal health of chicks
Qiongyi ZHANG ; Chanchan CUI ; Shijia ZHANG ; Xiao WANG ; Xicui DU ; Yongzhan BAO ; Wanyu SHI
Chinese Journal of Veterinary Science 2025;45(4):818-824
In order to investigate the effects of Fuzi Lizhong Oral liquid on immune function and in-testinal health of chicks,185 1-day-old healthy chicks were randomly divided into 4 groups.The blank control group(CG group)was given normal tap water;the high,medium and low dose groups(FZH group,FZM group and FZL group)were given tap water containing 5.00,2.50 and 1.25 g/L of Fuzi Lizhong Oral liquid,respectively.Starting from the first day of age,the drug was administered continuously for 5 d,and the blood was collected from the subwing vein on the sixth day of the test.The results showed that compared with CG group,thymus index in FZH group was significantly increased(P<0.05).Compared with CG group,serum IgM,IgG and sIgA in FZH group were significantly increased(P<0.05),and serum IgG and sIgA in FZM group were signifi-cantly increased(P<0.05).Compared with CG group,the relative expression of Occludin and Claudin-1 mRNA in FZH group was significantly increased(P<0.05),and the relative expression of ZO-1 mRNA in FZM and FZH groups was significantly increased(P<0.05).Compared with CG group,Shannon index of FZH group was significantly increased(P<0.05),Simpson index of FZH group was significantly decreased(P<0.05),and many beneficial bacteria such as Strepto-coccus spinosus,Eubacillus spinosus and Lactobacillus spinosus played a synergistic role.The results showed that adding 5.00 g/L Fuzi Lizhong Oral liquid in drinking water could improve the immunity of chicks,maintain the intestinal barrier function of chicks,increase the intestinal flora richness and promote the intestinal health of chicks.
4.Effects of Shenling Baizhu Oral Liquid on intestinal barrier and intestinal flora of broilers
Chanchan CUI ; Shijia ZHANG ; Qiongyi ZHANG ; Xiao WANG ; Xicui DU ; Wanyu SHI ; Yongzhan BAO ; Fuxing CHEN
Chinese Journal of Veterinary Science 2025;45(5):1045-1052
A total of 300 1-day-old broilers were randomly divided into 5 groups with 5 replicates per group and 12 broilers per replicate.The control group was given free drinking water(CG),the astragalus polysaccharide control group(HPS)received 0.8 mL/L of astragalus polysaccharide o-ral liquid in drinking water,and the experimental groups(SBL,SBM,SBH)received 1.5,3.0,4.5 mL/,of Shenling Baizhu Oral Liquid in drinking water.The results showed as follows:com-pared to the CG group,SIgA content in HPS group,group SBM and group SBH was significantly increased(P<0.05),IL-6 and IL-1β contents were significantly decreased(P<0.05),Occludin,Mucin-2 and Bcl-2 contents were significantly increased(P<0.05).The results of 16S rRNA test showed that the specific OUT number in groups HPS and SBM was significantly higher than that in group CG(P<0.05),α diversity analysis showed that compared with group CG,Chao1 index and Simpson index of group HPS,group SBM and group SBH were significantly increased,and βdiversity analysis showed that there were significant differences in species composition between test group and blank control group(P<0.05).The relative abundance analysis at the phylum level showed that the relative abundance of Firmicutes and Bacteroides in groups SBM and SBH was significantly higher than that in group CG(P<0.05).The above results showed that Shenling Baizhu Oral Liquid could improve the intestinal health and enhance the resistance of broilers.
5.Morphologic improvements of trachea of children with congenital tracheal stenosis after slide tracheoplasty
Wanyu WEN ; Xinwei DU ; Shunmin WANG ; Zhiwei XU ; Zhaohui LU
Chinese Journal of Thoracic and Cardiovascular Surgery 2022;38(7):402-408
Objective:To study the changes of stenotic segment trachea diameter, trachea length and carina angle before and after slide tracheoplasty.Methods:From January 2010 to January 2018, 77 children with congenital tracheal stenosis(female=36) with complete clinical data accepted slide tracheoplasty in Shanghai Children's Medical Center were selected as the observation group. The diameter of stenosis segment, the length of stenosis segment, the full length of trachea and carina angle were measured by CT image, and the ratio of stenosis segment length to full trachea length was calculated. A group of children with normal trachea morphology and the same sample number, and they had no significant difference in age, height and weight were selected as the control group.Results:The median operative age of 77 children in the observation group was 1.3(1.1, 1.9)years old, the height was 76.0(72.0, 83.0)cm, and the weight was 9.0(7.9, 10.8)kg. The age, height and weight of 77 children in the control group were 1.5(1.0, 2.0) years old and 78.0(71.0, 85.0) cm, 9.2(7.9, 11.0) kg respectively. After slide tracheoplasty, the diameter of trachea in the stenotic segment of children increased from 2.7 mm to 4.4 mm, which was increased by 63.0%( P<0.001), but still smaller than that of children in the control group(6.1 mm). The average length of trachea was shortened by 0.7 cm( P<0.001), and there was no significant difference between the total length of trachea(5.4 cm) and the total length of trachea(5.5 cm). The postoperative carina angle decreased by 27.9°( P<0.001), there was no significant difference in postoperative carina angle between the observation group(93.0°) and the control group(90.7°). Conclusion:The diameter of reconstructed trachea in children with CTS is significantly increased, the length and carina angle of trachea become smaller after slide tracheoplasty. The morphology of trachea is more similar to children in the control group.
6.Effect of hyperbaric oxygen on delayed neuropsychiatric sequelae followed carbon monoxide poisoning
Yanjie ZHANG ; Ganqin DU ; Jinpeng GUO ; Zaihang ZHANG ; Wanyu ZHAO
Chinese Journal of Emergency Medicine 2018;27(7):794-798
Objective To explore the effect of different hyperbaric oxygen treatment (HBOT) on delayed neuropsychiatric sequelae followed carbon monoxide (CO) poisoning (DNS).Methods Patients diagnosed acute carbon monoxide poisoning (ACOP) or DNS due to CO poisoning in the hospital from October 2015 to October 2016 were included.Patients who died of ACOP or in persisting unconsciousness condition were excluded.Information of the patients were retrospectively collected including personal data,clinical features and treatment course of hyperbaric oxygen (HBO).All subjects were divided into two groups,consisting of cases who developed into DNS and who fully recovered,according toclinical symptoms.The differences of personal data,clinical features and treatment course of HBO were compared between the two groups.After adjusting the confounding factors,hyperbaric oxygen treatment program of the two groups were analyzed.Results DNS occurred in 39 patients with acute CO poisoning,while 130 patients were fully recovery.The ratio of patients over 55 years old or with smoking history in the DNS group were higher than that in the good outcome group (82.1% vs.60.8%,23.1% vs.10.8%).Patients who awoke from unconsciousness but left cognitive impairment were more likely to develop into DNS (P=0.017).Patients who treated with HBO within the first 24 hours,risk of developing into DNS were decreased(OR=0.14,P<0.01).At the same time,2 times per day and within the first 24 hours worked also as well.(OR=0.29,P=0.011).Even if patients who were given 2 times a day of HBO but not in the first 24 hours after poisoning,could not reduce the risk of evolving to DNS(OR=0.06,P>0.05);The proportion of patients in the good outcome group accepted HBO for more than six days after poisoning was higher than that in the DNS group (68.5% vs.48.7%).After adjusting confounding factors,patients who treated with HBO within the first 24 hours (OR=0.22,95%CI:0.09-0.52),2 times per day(OR=0.30,95%CI:0.10-0.87)and lasted for more than 6 days(OR=0.30,95%CI:0.10-0.87)were in a lower risk of involving to DNS.Conclusions For patients diagnosed ACOP,HBOT began in the first 24 hours,1 or 2 times per day or early sustaining to give HBO for more than 6 days could reduce the risk of DNS.
7. The level of formaldehyde in the air of the anatomic laboratories and its prevention measures
Hongmei QIU ; Jianwu CHEN ; Li TANG ; Hui WANG ; Wanyu DU ; Lin YANG ; Yuxing DU
China Occupational Medicine 2018;45(06):723-726
OBJECTIVE: To investigate the level of formaldehyde in the air of anatomical laboratories and to explore the effect of different prevention measures on reducing the level of formaldehyde. METHODS: The level of formaldehyde in two morphological laboratories of a medical college of a university were measured with a comprehensive atmospheric sampler at different physical ventilation time,different time after spraying biological enzymes and different masks. RESULTS: The level of formaldehyde decreased with the increase of ventilation time in front,middle and back of the laboratory( P < 0. 05).The level of formaldehyde at 30 and 60 minutes after spraying bio-enzymes in three parts of the laboratory was lower than that at 0 minute in the same part of the laboratory( P < 0. 05),and lower than that in the bio-enzymes non-spraying laboratory at the same part and same time point( P < 0. 05). At 0,30 and 60 minutes ventilation time points,the level of formaldehyde in the activated carbon mask group was lower than that in the normal sampling group,the non-woven mask group and the defatted gauze mask group at the same time point( P < 0. 05). CONCLUSION: Both physical ventilation and bio-enzyme degradation can reduce indoor formaldehyde pollution. Active carbon mask can achieve good protection effect.
8.Development of combat readiness archive kit
Chinese Medical Equipment Journal 2003;0(11):-
Currently, cadre information management has a development trend of digitalization and intelligentization. and this evolution Can meet the modern high-tech war demand that the cadres be rapidly regulated and high level persons with ability be reasonably equipped. New-generation combat readiness archive kit developed in this paper applies advanced protective apparel and related modern informatized device, and can improve the field usage and management of cadre archives.
9.Development of S2001 field operating table
Wanyu GAO ; Zhenjie DU ; Yingjie QIN
Chinese Medical Equipment Journal 1989;0(04):-
To meet the requirements of modern field first-aid operation, a field operating table, which can be wholly folded, is developed in this paper. The table consists of a bracket and a board. The trigonal bracket, with double arms, has an articulated shoring. The posture regulation part is composed of the wormwheel, worm, rocker of plate and shoring fittings of all segments of the table. According to the measurements of its dimensions and posture angle, military experiment, experiments for stability, load, regulation moment and simulate transportation on the third level of road, S2001 field operating table is suitable for the operations on head and cervix, chest and abdomen, limbs, urinary organs and the five sense organs, whose wholly-fold structure contributes to rapid deployment and undeployment in the field.

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