1.Asian Conference on Tumor Ablation Guidelines for Adrenal Tumor Ablation
Byung Kwan PARK ; Masashi FUJIMORI ; Shu-Huei SHEN ; Uei PUA
Endocrinology and Metabolism 2021;36(3):553-563
Thermal ablation is a good alternative treatment in patients who are unable to undergo adrenalectomy. Even though the Asian Conference on Tumor Ablation (ACTA) has been held for many years, adrenal ablation guidelines have not been established. No guidelines for adrenal ablation are established in American and European countries, either. The aim of this review was to introduce the first version of ACTA guidelines for adrenal tumor ablation.
2.Asian Conference on Tumor Ablation Guidelines for Adrenal Tumor Ablation
Byung Kwan PARK ; Masashi FUJIMORI ; Shu-Huei SHEN ; Uei PUA
Endocrinology and Metabolism 2021;36(3):553-563
Thermal ablation is a good alternative treatment in patients who are unable to undergo adrenalectomy. Even though the Asian Conference on Tumor Ablation (ACTA) has been held for many years, adrenal ablation guidelines have not been established. No guidelines for adrenal ablation are established in American and European countries, either. The aim of this review was to introduce the first version of ACTA guidelines for adrenal tumor ablation.
3.Is routine chest radiography necessary after ultrasonography-guided catheter thoracostomy?
Yong Quan Alvin SOON ; Kian Wei Alvin TAN ; Lakshmi KUMAR ; Uei PUA
Singapore medical journal 2021;62(1):16-19
INTRODUCTION:
Many institutions still perform routine chest radiography (CXR) after tube thoracostomies despite current guidelines suggesting that this is not necessary for simple cases. We aimed to evaluate the usefulness of routine CXR following ultrasonography-guided catheter thoracostomies for the detection of complications of symptomatic pleural effusions in hospitalised patients.
METHODS:
This was a retrospective review of 2,032 ultrasonography-guided thoracostomies on hospitalised patients with symptomatic effusions at a single institution from April 2012 to May 2015. The aetiology of effusions was not systemically registered, but patient demographics, procedural details and clinical outcomes were collected. Data was analysed using descriptive statistics and chi-square test. Generalised estimating equation analysis was performed to assess the relationship between CXR findings and complications while controlling for age.
RESULTS:
Out of 2,032 CXRs, 92.96% (n = 1,889) were normal, 5.81% (n = 118) showed pneumothorax and 1.23% (n = 25) showed catheter kinking. 99 pneumothoraces and 24 kinked catheters were detected in the first hour post procedure. 97.40% (n = 115) of patients with pneumothorax were stable or had minor complications, such as a vasovagal event. 0.20% (n = 4) of the cases had a serious complication following chest drain insertion, resulting in cardiovascular collapse. There was no significant relationship between CXR results and occurrence of complications (p = 0.244). Amount of fluid drained or side of insertion did not affect the clinical outcome.
CONCLUSION
Routine use of CXR after tube thoracostomy did not significantly change patient management, which was concordant with recent guidelines. Instead, adverse clinical outcomes or procedural factors should guide investigations.
5.Routine Staging Using Chest Computed Tomography in Workup of Treatment-Naïve Hepatocellular Carcinoma Prior to Locoregional Therapy: Is There a Need?
Po Wey LEONG ; Uei PUA ; Kian Soon LIM
Annals of the Academy of Medicine, Singapore 2017;46(7):282-286
INTRODUCTIONThe lung is the most common site of distal metastasis in patients with hepatocellular carcinoma (HCC), as seen in more than half of patients with extrahepatic disease. The incidence of pulmonary metastasis in all patients with HCC, however, remains low (between 4.5% to 20%). Their presence, nevertheless, contraindicates curative locoregional therapies. The role of staging chest computed tomography (CT) before locoregional treatment is not well defined. This study aimed to assess the utility of pre-treatment chest CT prior to locoregional therapy.
MATERIALS AND METHODSRetrospective review of continuous cases of treatment-naïve HCC referred for locoregional therapy from 2004 to 2013 was performed. Patients with pre-treatment chest CT were evaluated for the presence of pulmonary metastases. HCC features (size, numbers, vascular invasion, nodal status and bone metastases) were recorded. Univariate analysis and multivariate logistic regression were performed for significant association.
RESULTSA total of 780 patients were reviewed, of which 135 received staging chest CT. Pulmonary metastases (n = 17, 12.6%), benign lesions (n = 41, 30.4%) and indeterminate lesions (n = 11, 8.1%) were detected. Among the indeterminate lesions, there were losses to follow-up (n = 2) and deaths within the study period (n = 3). All patients with pulmonary metastases were declined locoregional therapy. Univariate analysis showed statistical significant association between pulmonary metastases with the number of intrahepatic lesions (<0.01), primary tumour size (= 0.018) and presence of vascular invasion (<0.01). On multivariate analysis, the number of intrahepatic lesions (OR: 9.7; 95% CI, 1.6 to 57.2;= 0.012) and presence of both hepatic and portal venous invasions (OR: 11.8; 95% CI, 1.1 to 128.8;= 0.043) were the 2 independent positive predictors of pulmonary metastases.
CONCLUSIONThe prevalence of pulmonary metastasis is low in HCC and our study does not support the routine use of staging chest CT in all treatment-naïve patients. It can, however, be considered in cases with multiple lesions or vascular invasion.
7.The role of multidetector computed tomography versus digital subtraction angiography in triaging care and management in abdominopelvic trauma.
James Thomas Patrick Decourcy HALLINAN ; Cher Heng TAN ; Uei PUA
Singapore medical journal 2016;57(9):497-502
INTRODUCTIONThis study aimed to assess the ability of contrast-enhanced computed tomography (CECT) to detect active abdominopelvic haemorrhage in patients with blunt trauma, as compared to digital subtraction angiography (DSA).
METHODSIn this retrospective study, patients who underwent DSA within 24 hours following CECT for blunt abdominal and/or pelvic trauma were identified. The computed tomography (CT) trauma protocol consisted of a portal venous phase scan without CT angiography; delayed phase study was performed if appropriate. All selected CECT studies were independently reviewed for the presence of active extravasation of contrast by two radiologists, who were blinded to the DSA results. Fisher's exact test was used to correlate the presence of extravasation on CT with subsequent confirmed haemorrhage on DSA.
RESULTSDuring the eight-year study period, 51 patients underwent CECT prior to emergent DSA for abdominal or pelvic trauma. Evidence of active extravasation of contrast on CECT was observed in 35 patients and active haemorrhage was confirmed on DSA in 31 of these patients; embolisation was performed in all 31 patients. Two patients who were negative for active extravasation of contrast on CECT but positive for active haemorrhage on DSA had extensive bilateral pelvic fractures and haematomas. The sensitivity, specificity, and positive and negative predictive values of CECT in detecting active abdominopelvic haemorrhage, as compared to DSA, were 93.9%, 77.8%, 88.6% and 87.5%, respectively.
CONCLUSIONWhen compared with DSA, dual-phase CECT without CT angiography shows high sensitivity and positive predictive value for the detection of active haemorrhage in patients with blunt abdominopelvic trauma.
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Angiography, Digital Subtraction ; Female ; Humans ; Male ; Middle Aged ; Multidetector Computed Tomography ; Observer Variation ; Pelvic Bones ; Pelvis ; injuries ; Radiology ; methods ; Retrospective Studies ; Wounds, Nonpenetrating ; diagnostic imaging ; Young Adult
8.RE: Irreversible Electroporation of a Hepatocellular Carcinoma Lesion Adjacent to a Transjugular Intrahepatic Portosystemic Shunt Stent Graft.
Korean Journal of Radiology 2014;15(1):181-182
No abstract available.
Carcinoma, Hepatocellular/*surgery
;
Electroporation/*methods
;
Humans
;
Liver Neoplasms/*surgery
;
Male
;
*Portasystemic Shunt, Transjugular Intrahepatic
;
*Stents
9.Rapid Intra-Hepatic Dissemination of Hepatocellular Carcinoma with Pulmonary Metastases Following Combined Loco-Regional Therapy.
Korean Journal of Radiology 2013;14(4):640-642
This manuscript describes an unusual case of rapid intra-hepatic dissemination of hepatocellular carcinoma with pulmonary metastases occurring 1 month after combined chemoembolization and radiofrequency ablation. Inferior vena cava and portal vein invasion tumor thrombus was also detected, possibly accounting for the mechanism of disease dissemination route of disease.
Aged, 80 and over
;
Antineoplastic Agents/administration & dosage/*adverse effects
;
Biopsy
;
Carcinoma, Hepatocellular/diagnosis/*secondary/therapy
;
Catheter Ablation/*adverse effects
;
Chemoembolization, Therapeutic/*adverse effects
;
Cone-Beam Computed Tomography
;
Fatal Outcome
;
Humans
;
Liver Neoplasms/*pathology/therapy
;
Lung Neoplasms/diagnosis/*secondary
;
Male
10.Modified Retroperitoneal Access for Percutaneous Intervention after Pancreaticoduodenectomy.
Korean Journal of Radiology 2013;14(3):446-450
Percutaneous access to the surgical bed after pancreaticoduodenectomy can be a challenge, due to the post-operative anatomy alteration. However, immediate complications, such as surgical bed abscess or suspected tumor recurrence, are often best accessed percutaneously, as open surgical or endoscopic approaches are often difficult, if not impossible. We, hereby, describe a safe approach that is highly replicable, in accessing the surgical bed for percutaneous intervention, following pancreaticoduodenectomy.
Abscess/radiography/therapy
;
Bile Duct Neoplasms/pathology/radiography
;
Biopsy/methods
;
Catheterization/*methods
;
Cholangiocarcinoma/pathology/radiography
;
Drainage/instrumentation/*methods
;
Humans
;
Male
;
Middle Aged
;
Neoplasm Recurrence, Local/pathology/radiography
;
Pancreatic Diseases/radiography/therapy
;
*Pancreaticoduodenectomy
;
Postoperative Complications/radiography/*therapy
;
Radiography, Interventional/methods
;
Retroperitoneal Space

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