1.Termination Processes of Pregnancies Due to Intrauterine Mort Fetus and Fetal Anomaly
Tugba AKCAOGLU ; Eren Elif CILER
Maternal-Fetal Medicine 2025;07(4):228-233
Objective::To compare pregnancy terminations for two reasons: intrauterine fetal death (IUFD) and fetal anomaly, focusing on obstetric data and termination processes to optimize clinical management.Methods::This retrospective, single-center study included singleton pregnancies terminated for intrauterine fetal death or fetal anomaly (≥ 10 weeks’ gestation) between January 2020 and December 2021. Demographic, obstetric, and procedural data were collected. Termination methods included misoprostol, balloon catheter, curettage, and hysterotomy, following FIGO guidelines. Feticide was performed when indicated. Statistical analysis was conducted using t-test, chi-square test, and Pearson correlation; significance was set at P < 0.050. Results::A total of 173 termination cases (104 IUFD, 69 fetal anomalies) were analyzed. Mean gestational age was 16.6 ± 4.2 weeks. Termination and hospitalization times were longer in anomaly cases ( P < 0.001). Gravida and parity were lower in the anomaly group ( P = 0.005, P = 0.011). Misoprostol use showed a positive correlation with termination time ( r = 0.251, P = 0.001); parity was negatively correlated ( r = –0.175, P = 0.021). Balloon, curettage, and feticide rates were higher in anomaly cases (all P < 0.001). Complications occurred in 4 patients (2.3%). Conclusion::Clinical approaches to pregnancy termination differ based on the underlying condition. Obstetric history and fetal pathology influence the methods and timing of the procedure, emphasizing the need for individualized care to improve patient outcomes.
2.Termination Processes of Pregnancies Due to Intrauterine Mort Fetus and Fetal Anomaly
Tugba AKCAOGLU ; Eren Elif CILER
Maternal-Fetal Medicine 2025;07(4):228-233
Objective::To compare pregnancy terminations for two reasons: intrauterine fetal death (IUFD) and fetal anomaly, focusing on obstetric data and termination processes to optimize clinical management.Methods::This retrospective, single-center study included singleton pregnancies terminated for intrauterine fetal death or fetal anomaly (≥ 10 weeks’ gestation) between January 2020 and December 2021. Demographic, obstetric, and procedural data were collected. Termination methods included misoprostol, balloon catheter, curettage, and hysterotomy, following FIGO guidelines. Feticide was performed when indicated. Statistical analysis was conducted using t-test, chi-square test, and Pearson correlation; significance was set at P < 0.050. Results::A total of 173 termination cases (104 IUFD, 69 fetal anomalies) were analyzed. Mean gestational age was 16.6 ± 4.2 weeks. Termination and hospitalization times were longer in anomaly cases ( P < 0.001). Gravida and parity were lower in the anomaly group ( P = 0.005, P = 0.011). Misoprostol use showed a positive correlation with termination time ( r = 0.251, P = 0.001); parity was negatively correlated ( r = –0.175, P = 0.021). Balloon, curettage, and feticide rates were higher in anomaly cases (all P < 0.001). Complications occurred in 4 patients (2.3%). Conclusion::Clinical approaches to pregnancy termination differ based on the underlying condition. Obstetric history and fetal pathology influence the methods and timing of the procedure, emphasizing the need for individualized care to improve patient outcomes.

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