The therapeutic effects of transcranial magnetic stimulation (TMS) are closely related to the structure of the stimulation coil. Based on this, this study designed an A-word coil and proposed a multi-strategy fusion multi-objective slime mould algorithm (MSSMA) aimed at optimizing the stimulation depth, focality, and intensity of the coil. MSSMA significantly improved the convergence and distribution of the algorithm by integrating a dual-elite guiding mechanism, a hyperbolic tangent control strategy, and a hybrid polynomial mutation strategy. Furthermore, compared with other stimulation coils, the novel coil optimized by the MSSMA demonstrates superior performance in terms of stimulation depth. To verify the optimization effects, a magnetic field measurement system was established, and a comparison of the measurement data with simulation data confirmed that the proposed algorithm could effectively optimize coil performance. In summary, this study provides a new approach for deep TMS, and the proposed algorithm holds significant reference value for multi-objective engineering optimization problems.
Algorithms ; Transcranial Magnetic Stimulation/instrumentation* ; Equipment Design ; Humans

Trans-cranial magnetic stimulation (TMS) is the process that excitable human brain tissue is activated with the electric field induced from a changing magnetic field. Magnetic focusing characteristic is one of the most important technical considerations of coil design in TMS. In this paper, a half solenoid coil was proposed to be used in TMS and the magnitude profile of the induced electric fields in different depth was studied based on the induced electric field theory of magnetic stimulating coil. The magnitude profile of the induced electric fields produced by half solenoid coils was compared with that of butterfly-shaped coils. The result shows that half solenoid coils retain the good focusing characteristics of the main lobe of the butterfly-shaped coils. At the same time side effect of the side lobes on notargeted tissue is mitigated, which would otherwise lead to undesirable stimulation. Hence magnetic focusing is optimized, which is expected to give a more accurate delivery of the focal point for more effective stimulation.
Brain ; physiology ; Electromagnetic Fields ; Equipment Design ; Humans ; Transcranial Magnetic Stimulation ; instrumentation

Transcranial magnetic stimulation (TMS) is a non-invasive diagnostic and therapeutic technigue. This paper expounds the design and manufacture of the TMS system, which meets all the requirements of the TMS study and clinical diagnosis and treatments.
Cerebral Cortex ; physiology ; Electric Stimulation ; instrumentation ; Electromagnetic Fields ; Equipment Design ; Humans ; Transcranial Magnetic Stimulation ; instrumentation

It is the intent of this paper to locate the activation point in Transcranial Magnetic Stimulation (TMS) efficiently. The schemes of coil array in torus shape is presented to get the electromagnetic field distribution with ideal focusing capability. Then an improved adaptive genetic algorithm (AGA) is applied to the optimization of both value and phase of the current infused in each coil. Based on the calculated results of the optimized current configurations, ideal focusing capability is drawn as contour lines and 3-D mesh charts of magnitude of both magnetic and electric field within the calculation area. It is shown that the coil array has good capability to establish focused shape of electromagnetic distribution. In addition, it is also demonstrated that the coil array has the capability to focus on two or more targets simultaneously.
Algorithms ; Brain ; physiology ; Electric Stimulation ; instrumentation ; Electromagnetic Fields ; Equipment Design ; Evoked Potentials, Motor ; physiology ; Humans ; Neurons ; physiology ; Transcranial Magnetic Stimulation