[Objective]To summarize WU Guowei's clinical experience in treating IgA nephropathy.[Methods]Analyze WU Guowei's diagnosis and treatment of IgA nephropathy,summarize his syndrome differentiation and treatment of IgA nephropathy,and analyze one typical case for proof.[Results]WU Guowei believes that the core pathogenesis of IgA nephropathy is deficiency of origin and substance,which is closely related to"wind,poison,stasis and deficiency".In the early stage or the onset of the disease,the evil substance of wind and poison is the main factor,and according to the different characteristics of different concurrence and toxin,it adopts different syndrome differentiation and treatment rules,while removing the evil,but also does not forget to strengthen the body resistance;In the middle and late stages of this disease,the spleen-kidney deficiency is the main factor,so the treatment is mainly to strengthen the spleen and kidney,and according to the difference of Yin and Yang deficiency,different treatment methods and prescriptions are taken.Stasis of kidney collateral is accompanied by the whole pathological process of the disease,so"promoting blood circulation and removing blood stasis"runs through the whole treatment.The attached medical case was edema,which was a syndrome of lung invaded by wind-heat and damp toxin,treated with opening wind,clearing heat and detoxification,relieving cough,promoting water and blood circulation,and achieved good curative effect.[Conclusion]WU Guowei's treatment of IgA nephropathy starts from"wind,poison,stasis and deficiency",and the combination of syndrome differentiation and disease differentiation has achieved remarkable curative effect.His clinical experience is worth learning and promoting.

[Objective]To summarize WU Guowei's clinical experience in treating IgA nephropathy.[Methods]Analyze WU Guowei's diagnosis and treatment of IgA nephropathy,summarize his syndrome differentiation and treatment of IgA nephropathy,and analyze one typical case for proof.[Results]WU Guowei believes that the core pathogenesis of IgA nephropathy is deficiency of origin and substance,which is closely related to"wind,poison,stasis and deficiency".In the early stage or the onset of the disease,the evil substance of wind and poison is the main factor,and according to the different characteristics of different concurrence and toxin,it adopts different syndrome differentiation and treatment rules,while removing the evil,but also does not forget to strengthen the body resistance;In the middle and late stages of this disease,the spleen-kidney deficiency is the main factor,so the treatment is mainly to strengthen the spleen and kidney,and according to the difference of Yin and Yang deficiency,different treatment methods and prescriptions are taken.Stasis of kidney collateral is accompanied by the whole pathological process of the disease,so"promoting blood circulation and removing blood stasis"runs through the whole treatment.The attached medical case was edema,which was a syndrome of lung invaded by wind-heat and damp toxin,treated with opening wind,clearing heat and detoxification,relieving cough,promoting water and blood circulation,and achieved good curative effect.[Conclusion]WU Guowei's treatment of IgA nephropathy starts from"wind,poison,stasis and deficiency",and the combination of syndrome differentiation and disease differentiation has achieved remarkable curative effect.His clinical experience is worth learning and promoting.

Type B insulin resistance syndrome(TBIR)is a rare autoimmune disease caused by the presence of autoantibodies against insulin receptors in the human body,leading to severe refractory hyperglycemia or refractory hypoglycemia.This article reports a case of TBIR patient,summarizes and analyzes its epidemiological characteristics and diagnosis and treatment methods,providing a basis for clinical treatment.