Objective:To explore the aperiodic components(1/f slopes)and their associations with cognitive impairment in patients with schizophrenia.Methods:Nineteen patients with schizophrenia according to the Interna-tional Statistical Classification of Diseases and Related Health Problem,Tenth Revision(ICD-10)and 21 normal controls were administrated the total Brief Assessment of Cognition in Schizophrenia(BACS)to measure the cogni-tive performance.The 5-minute eyes-closed and eyes-open resting EEG signals were collected and parameterized in-to aperiodic components(1/f slope).Finally,Pearson correlation was used to examine the relationships between the 1/f slope and cognition assessment scores.Results:The patients with schizophrenia had higher 1/f slope compared to HC on central location of scalp(P＜0.05).The vocal memory scores showed a significantly positive relation with 1/f slopes in patients with schizophrenia(anterior location:r=-0.68,P＜0.05;central location:r=-0.44,P＜0.05),but a significantly negative relation in normal controls(anterior location:r=0.57,P＜0.05;posterior lo-cation:r=0.54,P＜0.05).Conclusion:The 1/f slopes of EEG in schizophrenia were steeper than normal control,suggesting its strong cognitive functional significance and complex mechanisms in schizophrenia.

Objective:To explore the aperiodic components(1/f slopes)and their associations with cognitive impairment in patients with schizophrenia.Methods:Nineteen patients with schizophrenia according to the Interna-tional Statistical Classification of Diseases and Related Health Problem,Tenth Revision(ICD-10)and 21 normal controls were administrated the total Brief Assessment of Cognition in Schizophrenia(BACS)to measure the cogni-tive performance.The 5-minute eyes-closed and eyes-open resting EEG signals were collected and parameterized in-to aperiodic components(1/f slope).Finally,Pearson correlation was used to examine the relationships between the 1/f slope and cognition assessment scores.Results:The patients with schizophrenia had higher 1/f slope compared to HC on central location of scalp(P＜0.05).The vocal memory scores showed a significantly positive relation with 1/f slopes in patients with schizophrenia(anterior location:r=-0.68,P＜0.05;central location:r=-0.44,P＜0.05),but a significantly negative relation in normal controls(anterior location:r=0.57,P＜0.05;posterior lo-cation:r=0.54,P＜0.05).Conclusion:The 1/f slopes of EEG in schizophrenia were steeper than normal control,suggesting its strong cognitive functional significance and complex mechanisms in schizophrenia.

Objective To investigate the current status of compassion fatigue among nurses in the geriatrics department of a tertiary hospital in Chongqing,analyze its influencing factors,and construct a predictive model.Methods A total of 39 nurses from the geriatrics department were enrolled as study participants.General demographic data were collected,and the Chi-nese versions of the Compassion Fatigue Scale,Big Five Personality Scale,and Social Support Rating Scale were used to assess the nurses'compassion fatigue,Big Five personality traits,and social support.A logistic regression model was constructed to ana-lyze the data.Results Among the 39 nurses,31 experienced compassion fatigue,with an incidence rate of 79.49％.Univariate analysis revealed that average daily working hours,income satisfaction,job satisfaction,and sleep quality had significant impacts on the occurrence of compassion fatigue(P＜0.05).Correlation analysis showed that compassion satisfaction scores were posi-tively correlated with conscientiousness and negatively correlated with neuroticism.Multiple regression analysis confirmed the sig-nificant relationship between neuroticism and compassion satisfaction.The regression equation was established as follows:Com-passion Satisfaction Score=28.104-4.111 x Average Daily Working Hours-2.171 x Income Satisfaction-2.83 x Job Satis-faction-0.226 x Sleep Quality-0.452 x Neuroticism Score+0.721 x Conscientiousness Score+0.176 x Subjective Support Score+0.684 x Support Utilization.Conclusion Neuroticism is an independent influencing factor of compassion fatigue among nurses in the geriatrics department.The constructed logistic regression model provides valuable reference for the management of compassion fatigue and offers new scientific evidence for the early clinical identification of nurses at risk of compassion fatigue.

The development of health-promoting hospitals is an important part of the Healthy China Initiative， facilitating the transformation of medical institutions from a primary focus on medical and surgical treatments to a patient-centered approach prioritizing public health. To promote the scientific， standardized， and sustainable development of health-promoting hospitals， the Shanghai Municipal Center for Health Promotion， together with Shanghai General Hospital and other institutions， has jointly developed the Standards for the Development of Health⁃promoting Hospitals （Standards） in accordance with the principles of scientific rigor， feasibility， and advancing with the times. The Standards outlines the requirements for the development of health-promoting hospitals across four aspects： organizational and institutional guarantees， creation of a healthy environment， implementation of health education and promotion， and evaluation. It is applicable to all levels and types of public medical institutions in Shanghai， and can also be referred to and implemented by other medical institutions. The introduction of the Standards is of great significance for promoting the formation of a long-term mechanism in health-promoting hospitals. This paper introduces the basis， principles， main content， precautions， and implementation suggestions of the Standards. Taking into account relevant policies and standards， it interprets the technical aspects in the process of developing health-promoting hospitals， which is helpful for medical institutions and their management to better understand and apply the standards in their work.

Objective To investigate the current status of compassion fatigue among nurses in the geriatrics department of a tertiary hospital in Chongqing,analyze its influencing factors,and construct a predictive model.Methods A total of 39 nurses from the geriatrics department were enrolled as study participants.General demographic data were collected,and the Chi-nese versions of the Compassion Fatigue Scale,Big Five Personality Scale,and Social Support Rating Scale were used to assess the nurses'compassion fatigue,Big Five personality traits,and social support.A logistic regression model was constructed to ana-lyze the data.Results Among the 39 nurses,31 experienced compassion fatigue,with an incidence rate of 79.49％.Univariate analysis revealed that average daily working hours,income satisfaction,job satisfaction,and sleep quality had significant impacts on the occurrence of compassion fatigue(P＜0.05).Correlation analysis showed that compassion satisfaction scores were posi-tively correlated with conscientiousness and negatively correlated with neuroticism.Multiple regression analysis confirmed the sig-nificant relationship between neuroticism and compassion satisfaction.The regression equation was established as follows:Com-passion Satisfaction Score=28.104-4.111 x Average Daily Working Hours-2.171 x Income Satisfaction-2.83 x Job Satis-faction-0.226 x Sleep Quality-0.452 x Neuroticism Score+0.721 x Conscientiousness Score+0.176 x Subjective Support Score+0.684 x Support Utilization.Conclusion Neuroticism is an independent influencing factor of compassion fatigue among nurses in the geriatrics department.The constructed logistic regression model provides valuable reference for the management of compassion fatigue and offers new scientific evidence for the early clinical identification of nurses at risk of compassion fatigue.

Objective:To introduce a novel anatomical supra-pectineal quadrilateral surface buttress plate, and explore its advantages, disadvantages and clinical efficacy in the treatment of complex acetabular fractures.Methods:Data of eighteen cases of acetabular fractures treated in our department from March 2017 to March 2019were retrospectively analyzed. There were 15 males and 3 females with an average age of 49.6 years (range, 27-62 years). According to the Letournel-Judet’s classification, there were 3 cases of anterior column fractures (involving quadrilateral surface), 2 cases of "T" shaped, 8 of cases anterior column and posterior hemi-transverse (ACPHT) and 5 cases of double columns fractures. The time from injury to operation was 5-14 days (mean, 7 days). Before operation, all patients were taken pelvic anterior-posterior X-ray and CT scan. All patients were adopted supra-ilioinguinal approach and fixed by supra-pectineal quadrilateral surface buttress plate. Surgical time, intraoperative blood loss and postoperative complications were collected. After operations all patients were taken pelvic X-ray in anterior-posterior and Judet position, as well as CT scan. The radiographic quality of reduction was evaluated by Matta criteria and hip functions were evaluated by Matta Modified Merle d’Aubigné-Postel scoring system.Results:The average surgical time was 130 min (range, 100-200 min). The average blood loss was 560 ml (range, 400-900 ml). An additional shaping was unnecessary in 18 patients who were implanted with the anatomical supra-pectineal quadrilateral surface buttress plate and all patients were operated successfully. All patients were followed up for an average time of 9 months (range, 6-15 months). The quality of fracture reduction was evaluated according to Matta standard, of which there were 11 cases excellent, 4 cases good, and 3 cases poor, with an excellent rate of 83.3% (15/18). At the latest follow-up, the function of the hip joint was evaluated according to the Matta Modified Merle d’Aubigné-Postel scoring system for a mean of 15.8 scores (range, 12-18 scores), of which there were 10 cases excellent, 6 cases good, 2 cases fair, with an excellent rate of 88.9% (16/18). All patients recovered well, and there were 2 cases of lateral femoral cutaneous nerve injury postoperative who had recovered one month later. There was no other postoperative complications.Conclusion:The anterior and posterior column and quadrilateral surface could be stabilized simultaneously by the anatomical supra-pectineal quadrilateral surface buttress plate without intraoperative shaping. Moreover, it is more likely to obtain a satisfactory clinical outcome by using this special plate with lower complications and rigid fixation. Therefore, it is a kind of internal fixation method worthy of promotion in the treatment of complex acetabular fractures.

1.15). Rosiglitazone at the concentration of 1.25 ?mol?L -1 augme nted the induction apoptosis of A549 cells by treatment with Cisplatin at variou s concentrations of 1.98 mg?L -1, 2.8 mg?L -1 and 4.0 mg?L -1 . A549 cells treated with Rosiglitazone at concentration of 1.25 ?mol?L -1 domostrated nuclear traslocations of PPAR? protein and down-regulation of Bcl-2 protein. Conclusion The ligand of PPAR? Rosiglitazone enhanc ed the inhibition of proliferation and induction of apoptosis by treatment with Cisplatin in A549 cells cultured in vitro. Activation of PPAR? protein and the down-regulation of Bcl-2 possiblely play an improtant role in chemosenstiz eic mechanism of Rosiglitazone in vitro.