Objective:To analyze the disease burden of liver cancer and its changing trends in China from 1990 to 2021,so as to provide support for optimizing policies related to the prevention,control and treatment of liver cancer.Methods:Using the data from the Global Burden of Disease Study 2021,a descriptive analysis was conducted on the mortality and disease burden of liver cancer among different genders and age groups in China from 1990 to 2021.Joinpoint Software was used to estimate the average annual changes in the incidence rate,prevalence rate,mortality rate and DALY rate of liver cancer,as well as the annual percentage changes of each index in different time periods,so as to analyze the changing trends of the disease burden of liver cancer in China.Results:In 2021,the prevalence rate of liver cancer in China was 13.29 per 100 000,the incidence rate was 9.52 per 100 000,the mortality rate was 8.53 per 100 000,and the DALY rate was 239.91 per 100 000.From 1990 to 2021,the age-standardized prevalence rate of liver cancer in China increased by an average of 0.02％per year,while the incidence rate,mortality rate and DALY rate decreased by an average of 0.31％,0.79％and 1.03％per year respectively.The incidence rate,prevalence rate,mortality rate and DALY rate of males were all higher than those of females.Conclusion:From 1990 to 2021,the age-standardized DALY rate of liver cancer in China showed a downward trend,and the decline rate was faster than the global level.Interventions on excessive alcohol consumption,smoking and drug abuse should be further strengthened.

Objective:To analyze the disease burden of liver cancer and its changing trends in China from 1990 to 2021,so as to provide support for optimizing policies related to the prevention,control and treatment of liver cancer.Methods:Using the data from the Global Burden of Disease Study 2021,a descriptive analysis was conducted on the mortality and disease burden of liver cancer among different genders and age groups in China from 1990 to 2021.Joinpoint Software was used to estimate the average annual changes in the incidence rate,prevalence rate,mortality rate and DALY rate of liver cancer,as well as the annual percentage changes of each index in different time periods,so as to analyze the changing trends of the disease burden of liver cancer in China.Results:In 2021,the prevalence rate of liver cancer in China was 13.29 per 100 000,the incidence rate was 9.52 per 100 000,the mortality rate was 8.53 per 100 000,and the DALY rate was 239.91 per 100 000.From 1990 to 2021,the age-standardized prevalence rate of liver cancer in China increased by an average of 0.02％per year,while the incidence rate,mortality rate and DALY rate decreased by an average of 0.31％,0.79％and 1.03％per year respectively.The incidence rate,prevalence rate,mortality rate and DALY rate of males were all higher than those of females.Conclusion:From 1990 to 2021,the age-standardized DALY rate of liver cancer in China showed a downward trend,and the decline rate was faster than the global level.Interventions on excessive alcohol consumption,smoking and drug abuse should be further strengthened.

Objective To observe the value of multimodal imaging for diagnosis of cardiac space-occupying lesions.Methods Data of 70 patients with cardiac space-occupying lesions who underwent echocardiography and cardiac CT(CCT)were retrospectively analyzed,among them 35 also underwent cardiac MRI(CMRI).The value of multimodal imaging for diagnosis of cardiac space-occupying lesions were explored according to the results of surgical pathology or clinical diagnosis.Results Among 70 cases,benign tumors were confirmed by surgical pathology in 43 cases,while malignant tumors were confirmed by surgical pathology in 3 cases and clinically diagnosed in 1 case.Meanwhile,non-tumor-occupying lesions were clinically diagnosed in 23 cases,all obviously shrunken after treatments.Among 70 cases,echocardiography correctly diagnosed 57 cases,misdiagnosed 8 cases and unclearly diagnosed 5 cases,with diagnostic accuracy rate of 81.43%(57/70).CCT correctly diagnosed 63 cases,misdiagnosed 4 cases but missed 3 cases,with diagnostic accuracy rate of 90.00%(63/70).CMRI outcomes in all 35 cases were consistent with surgical pathologic results,with diagnostic accuracy rate of 100%(35/35).Conclusion Multimodal imaging might provide objective evidences for diagnosis and treatment of cardiac space-occupying lesions.