As the national centralized volume-based procurement of drugs has become normalized and institutionalized,the number of antimicrobials listed in the centralized volume-based procurement catalog has also increased.The rational use of antimicrobials under the background of centralized volume-based procurement has gained significant attention in the industry.After repeated discussions based on pertinent national and Shandong provincial policies and regulations as well as prior centralized volume-based procurement management experience,the Professional Committee of Clinical Application of Antimicrobials of Shandong Pharmaceutical Association,the Quality Control Center of Hospital Infection Management of Shandong Province,and the Quality Control Center of Monitoring of Bacterial and Fungal Drug Resistance of Shandong Province organized experts in Shandong Province to complete this consensus.To provide a reference for centralized volume-based procurement of antimicrobials in Shandong Province and even domestic medical institutions,this consensus primarily entails the establishment of a centralized volume-based procurement management system for antimicrobials,selection rules and management of the antimicrobial list,declaration of centralized volume-based procurement varieties and task decomposition of antimicrobials,monitoring,and management of antimicrobial use in medical institutions,comprehensive evaluation of clinical applications of centralized volume-based procurement of antimicrobials based on real-world,training and education,corporate responsibility,etc.