A premenopausal woman witj multiple risk factors for endometrial cancer, diagnosed with giant endometrial polyp with benign features on preoperative biopsy is presented. On hysteroscopy, intraoperative frozen section revealed a benign polyp, but was malignant on final histopathology. Definitive surgery yielded simple hyperplasia and endometrial polyp. Giant endometrial polyp grows to 9-12cm diameter. Complications in hysterosocopic removal of giant polyps are higher risk of perforation, more blood loss, hyponatremia, pulmonary edema, and hyperglycemia. All associated with dificult visualization and prolonged surgery. Frozen section of endometrial mass may help in instituting appropriate treatment. Local studies show high accuracy, although some reports were conflicting. In case of malignancy, maintenace of intrauterine pressure distention to less than 70mm Hg prevents dissemination of cancer cells. The hyperestogenic state seen in obesity with uncontrolled hypertension, diabetes, nulliparity and vaginal bleeding were associated in developing endometrial cancer arising from endometrial polyp resected by hysteroscopy.
Human ; Female ; Middle Aged ; CARCINOMA, ENDOMETRIOID ; HYSTEROSCOPY ; ENDOMETRIAL NEOPLASMS

<p style="text-align: justify;">A 21-year old commercial sex worker, G2P1(0101) presented at 20·21 weeks of gestation with a rapidly enlarging infected cauliflower-like vulvar mass. Infection and anemia were managed and followed by surgical excision of the vulvar mass. One week postoperatively, intrauterine fetal demise occurred and the patient delivered spontaneously after 2 weeks (beginning tumor regrowth was seen at this time). Preliminary histopathologic findings showed Condyloma acuminata and treatment with an immune modifier cream was started but there was no response. Further evaluation of histopathologic result led to the final diagnosis of giant Condyloma acuminata of Buschke and Lowenstein/Verrucous carcinoma. There was rapid enlargement of the tumor in six weeks, despite medical treatment, with enlargement of bilateral inguinal lymph nodes. A radical vulvectomy with bilateral groin node dissection was done.This successfully treated the tumor with no recurrence on her 6th month follow up.p>
Human ; Female ; Adult ; Groin ; Vulvectomy ; Sex Work ; Buschke-lowenstein Tumor ; Carcinoma, Verrucous ; Condylomata Acuminata ; Vulva ; Lymph Nodes ; Anemia ; Fetal Death ; Brassica