Objective: To explore the correlation of balance ability with short term memory and executive function among college students, so as to provide a theoretical basis for balance training and cognitive enhancement in college students. Methods: In November 2024, 80 college students were recruited from Chongqing Normal University. The dynamic and static balance abilities were measured using the Y-balance test(YBT) and PhysioSensing equipment. Short term memory and executive function were assessed through the digital span test, trail making test(TMT) and Stroop colour-word task. Pearson or Spearman analysis was used to explore the correlation between balance ability and cognitive function among college students. Results: The comprehensive scores of the balance YBT for college students were as follows: left side (95.14±5.93)% and right side (95.17±5.24)%.The average sway velocity of static balance under the conditions of stable surface with eyes open, stable surface with eyes closed, unstable surface with eyes open and unstable surface with eyes closed were 27.58(20.45, 37.64), 23.56(17.57, 34.77), 61.15(40.73, 78.05), 55.88 (40.84, 66.65)mm/s. The comprehensive scores of the YBT for both lower limbs in college students were negatively correlated with the time taken for TMT Part A (TMT-A), TMT Part B (TMT-B), and the difference in time spent between TMT-A and TMT-B (TMT-D) ( r =-0.55 to -0.24，all P <0.05). The average sway velocity under the four conditions was positively correlated with TMT-A, TMT-B, TMT-D, consistent reaction time, conflict reaction time and reaction time difference ( r =0.26-0.69，all P < 0.05). Under conditions of normal vestibular sensation with proprioception interference, the visual contribution in college students was negatively correlated with TMT-A, TMT-B, conflict reaction time and reaction time difference ( r =-0.28 to -0.22,all P < 0.05 ). Under conditions of normal vision and vestibular sensation, the proprioception contribution in college students was positively correlated with TMT-A, TMT-B, consistent reaction time, conflict reaction time and reaction time difference( r =0.26-0.39,all P < 0.05). Under conditions of normal vestibular sensation with visual interference, the proprioception contribution in college students was positively correlated with consistent reaction time and conflict reaction time ( r =0.24, 0.25,both P <0.05). Conclusions There is a correlation between balance ability and executive function in college students. When maintaining static balance, if the visual or proprioceptive system is interfered with, college students with poorer executive function rely more on other systems for compensation.

ObjectiveTo systematically investigate the discrepancies between employment preferences and actual job placements among postgraduate students in rehabilitation medicine, explore the influencing factors, and elucidate the underlying mechanisms of their employment decisions. MethodsA cross-sectional questionnaire survey was conducted among 100 full-time postgraduate students who had graduated from Capital Medical University School of Rehabilitation in the past six years. A self-designed questionnaire was used to collect information on personal background, self-assessed competencies, employment preferences, and actual job placements. Logistic regression models were employed to analyze the factors influencing employment preferences and actual job placements, respectively. ResultsEmployment preferences among rehabilitation medicine postgraduates were highly concentrated on large tertiary hospitals (79.0%), yet the actual placement rate (61.0%) showed a significant gap. Preference for tertiary hospitals showed no significant association with individual factors such as gender, degree type or self-assessed competencies (P > 0.05). Univariate analysis revealed that those who entered tertiary hospitals scored significantly higher in self-assessed clinical skills, research ability, communication and coordination, and resource integration (|t| > 3.661, P < 0.001), and demonstrated clearer career planning (P = 0.012). Multivariate logistic regression analysis did not identify any independent predictors of actual employment within the context of this study sample (P > 0.05). ConclusionEmployment among rehabilitation medicine postgraduates is characterized by highly homogeneous preferences coexisting with complexity of factors influencing actual employment. It is recommended to optimize the training system, deepen personalized career education, and establish diversified employment guidance mechanisms to promote rational talent flow and facilitate the balanced development of the rehabilitation medical service system.

Objective To evaluate the efficacy of minimally invasive neuroendoscopy combined with intraventricular drainage in the treatment of intraventricular hemorrhage.Methods A retrospective analysis was conducted on the clinical data of 88 patients with intraventricular hemorrhage who underwent surgical treatment from January 2018 to December 2023.All patients received bilateral ventricular indwelling external drainage tubes.Among them,37 cases were included in the endoscopy group.The bleeding side or side with more blood accumulation underwent a midline fistula.With the assistance of neuroendoscopy,the intraventricular blood clots were removed and a ventricular drainage tube was inserted.The contralateral ventricle was punctured and a ventricular drainage tube was inserted;The remaining 51 cases were included in the drainage group,in which bilateral ventricular drainage tubes were placed according to the traditional intraventricular drainage protocol.Results There was no significant statistical difference(P>0.05)between the endoscopic group and the drainage group in terms of mortality rate(10.8%vs.13.7%),rebleeding rate(8.1%vs.11.8%,P=0.576),intracranial infection rate(10.8%vs.17.6%,P=0.372),and hydrocephalus rate(10.8%vs.23.5%,P=0.166).Similarly,no significant statistical difference was found in the total hospitalization cost between the endoscopy group and the drainage group[(90700±73000)yuan vs.(99500±66000)yuan]and the GOS score during the 6-month follow-up(3.16±1.14 vs 3.02±1.12)showed(P>0.05).However,the postoperative GCS score improvement was significantly better in the endoscopic group than in the drainage group[2.00(2.00,4.00)vs.1.00(0.00,3.00),P=0.002].The duration of the extracranial drainage catheter placement was significantly shorter in the endoscopic group than in the drainage group[(7.16±2.99)days vs.(10.12±3.93)days,P<0.001].Conclusion Neuroendoscopy-assisted evacuation of intraventricular hemorrhage facilitates effective hematoma clearance,reduces the duration of ventricular drainage catheterization,and may contribute to improved patient outcomes.

Objective:To investigate the current situation and influencing factors of work ability in gynecological cancer patients, so as to provide a reference for occupational rehabilitation management of cancer patients.Methods:A total of 183 gynecological cancer patients who visited the gynecological oncology outpatient department of Women′s Hospital of Nanjing Medical University from November 2022 to March 2023 were selected by the convenience sampling. The General Information Questionnaire, Return-to-Work Self-efficacy Questionnaire, Social Support Rating Scale, the European Organization for Research and Treatment of Cancer Quality of Life Quesionnaire Core 30, Work Ability Index were selected for cross-sectional investigaton. The multiple linear regression analysis was used to explore the influencing factors of work ability in gynecological cancer patients.Results:A total of 189 questionnaires were sent out in this study, and 183 were effectively collected, with an effective recovery rate of 96.83% (183/189). The patients were (44.64 ± 7.06) years old. The scores of the patients were (27.77 ± 7.58) points on Work Ability Index, (4.72 ± 1.14) points on Return-to-Work Self-efficacy Questionnaire, (86.93 ± 23.44) points on Social Support Rating Scale, (79.46 ± 19.53) points on overall health status area and (41.23 ± 27.80) points on the field of fatigue symptoms area of the European Organization for Research and Treatment of Cancer Quality of Life Quesionnaire Core 30. Multiple linear regression analysis showed that fatigue, comorbidities, clinical stage of disease, primary treatment, per capita monthly income of families, return-to-work self efficacy and job nature were independent influencing factors of work ability in gynecological cancer patients ( t values were -10.47-2.86, all P<0.05), which explained 67.9% of the total variance. Conclusions:Clinical medical staff should pay attention to the influencing factors that affect work ability in gynecological cancer patients, in order to take targeted occupational rehabilitation measures to improve their work ability.

Objective To observe the value of 2D SECara-Net and 3D U2-Net models constructed based on 2D maximal intensity projection(MIP)and 3D time-of-flight MR angiography(3D TOF-MRA)images,respectively,also of their combination for MRA detecting unruptured saccular intracranial aneurysms(USIA).Methods Totally 973 patients with single USIA and 300 subjects who underwent healthy physical examination were retrospectively collected and divided into training set(n=923,containing 723 cases of USIA and 200 healthy subjects)and test set(n=350,containing 250 cases of USIA and 100 healthy subjects)at the ratio of 7:3.Pre-processed 3D TOF-MRA and the obtained 2D-MIP images in training set were imported into 3D U2-Net and 2D SECara-Net models for training and adjusting parameters,respectively.The efficiency of 2 models and their combination for detecting USIA were evaluated.Results The sensitivity,specificity and accuracy of 2D SECara-Net model for detecting USIA in test set was 78.80％(197/250),95.00％(95/100)and 83.43％(292/350),of 3D U2-Net model was 82.80％(207/250),86.00％(86/100)and 83.71％(293/350),respectively.The specificity of 2D SECara-Net model was higher than that of 3D U2-Net model(P=0.030),while no significant difference of sensitivity nor accuracy was found between 2 models(both P＞0.05).The specificity of the combination of the 2 models was 99.00％(99/100),higher than that of 3D U2-Net model(P＜0.05),and the sensitivity and accuracy of the combination was 91.20％(228/250)and 93.43％(327/350),respectivelty,both higher than those of 2 single models(all P＜0.05).Conclusion 2D SECara-Net and 3D U2-Net models had similar,sensitivity and accuracy for MRA detecting USIA.Combination of them could improve the detecting efficacy.

Objective The biomechanical performance of Ilizarov fixator models with different configurations for humeral shaft defect was compared,so as to provide a biomechanical basis for selecting the appropriate circular external fixation structure for the clinical treatment of humeral shaft defects using Ilizarov technology.Methods Based on CT data of the humerus from a healthy volunteer,the external fixators with three configurations,namely,hybrid frame,semi-ring frame and 90° fan frame were established.The finite element method was used to simulate the displacement and stress distribution under different loading conditions,and the finite element results were validated by biomechanical tests.Results Finite element analysis results:in terms of displacement,under compression,tensile and torque conditions,the displacement of 90° fan model was smaller than that of hybrid and semi-ring models.In terms of stress,the 90° fan model had the smallest displacement under tensile condition.In compression and torque tests,the semi-annular model had the lowest stress.Biomechanical test results:the semi-ring model exhibited the smallest displacement under axial compression,but there was no significant difference between the three models(P＞0.05).Conclusions The semi-ring and 90° fan frames can achieve a similar stability as the traditional hybrid frame through the strategy of'reducing the ring and increasing the stem'.The unilateral structure of the 90° fan frame has the advantages of small size,light weight,and structural stability,as well as a small impact on the shoulder and elbow joints,which makes it more valuable in clinical applications.

Objective To evaluate the efficacy of minimally invasive neuroendoscopy combined with intraventricular drainage in the treatment of intraventricular hemorrhage.Methods A retrospective analysis was conducted on the clinical data of 88 patients with intraventricular hemorrhage who underwent surgical treatment from January 2018 to December 2023.All patients received bilateral ventricular indwelling external drainage tubes.Among them,37 cases were included in the endoscopy group.The bleeding side or side with more blood accumulation underwent a midline fistula.With the assistance of neuroendoscopy,the intraventricular blood clots were removed and a ventricular drainage tube was inserted.The contralateral ventricle was punctured and a ventricular drainage tube was inserted;The remaining 51 cases were included in the drainage group,in which bilateral ventricular drainage tubes were placed according to the traditional intraventricular drainage protocol.Results There was no significant statistical difference(P>0.05)between the endoscopic group and the drainage group in terms of mortality rate(10.8%vs.13.7%),rebleeding rate(8.1%vs.11.8%,P=0.576),intracranial infection rate(10.8%vs.17.6%,P=0.372),and hydrocephalus rate(10.8%vs.23.5%,P=0.166).Similarly,no significant statistical difference was found in the total hospitalization cost between the endoscopy group and the drainage group[(90700±73000)yuan vs.(99500±66000)yuan]and the GOS score during the 6-month follow-up(3.16±1.14 vs 3.02±1.12)showed(P>0.05).However,the postoperative GCS score improvement was significantly better in the endoscopic group than in the drainage group[2.00(2.00,4.00)vs.1.00(0.00,3.00),P=0.002].The duration of the extracranial drainage catheter placement was significantly shorter in the endoscopic group than in the drainage group[(7.16±2.99)days vs.(10.12±3.93)days,P<0.001].Conclusion Neuroendoscopy-assisted evacuation of intraventricular hemorrhage facilitates effective hematoma clearance,reduces the duration of ventricular drainage catheterization,and may contribute to improved patient outcomes.

Metastatic Crohn's disease (MCD) represents one of the rare cutaneous extraintestinal manifestations in patients with Crohn's disease. The genital area, particularly the vulva in females, is the most commonly affected site in MCD. However, clinical cases of metastatic vulval Crohn's disease (MVCD) are relatively scarce, and the symptoms often lack specificity, making differential diagnosis challenging. This article aims to summarize the clinical characteristics, diagnostic approaches, and treatment modalities of MVCD, thereby providing a reference for the clinical management of this condition.

Objective To study the relationship between irisin and the risk of sarcopenia in elderly patients with hyperhomocysteine-mia of different genders.Methods A retrospective study was conducted on 180 elderly patients with hyperhomocysteinemia who were ad-mitted to the Geriatrics Department of the First Hospital of Lanzhou University between January 2021 and January 2023.The study partici-pants were categorized into the male sarcopenia group(n=43)and the male non-sarcopenia group(n=57),the female sarcopenia group(n=44),and the female non-sarcopenia group(n=36)according to the《2019 Consensus Update on the Diagnosis and Treat-ment of Sarcopenia》.Serum irisin levels were measured by enzyme-linked immunosorbent assay,and the clinical data of patients in sar-copenia and non-sarcopenia groups were compared under different genders.Serum irisin concentrations were grouped into quartiles,and the differences in the indicators related to sarcopenia[appendicular skeletal muscle mass index(ASMI),grip strength,and step speed]were statistically assessed among the four groups using analysis of ANOVA or the Kruskal-Wallis test.Multifactorial Logistic regression a-nalysis was used to evaluate the influencing factors of sarcopenia in elderly patients with hyperhomocysteinemia of different genders.Results Among elderly male patients,there were statistically significant differences in age,irisin,hemoglobin,total protein,albumin,triglycerides,High-density lipoprotein cholesterol,ASMI and percent body fat between the sarcopenia group and the non-sarcopenia group(P＜0.05).Among elderly female patients,there were statistically significant differences in irisin,C-reactive protein,platelets count,uric acid,ASMI and percent body fat between the sarcopenia group and the non-sarcopenia group(P＜0.05).After statistical a-nalysis,it was found that the ASMI was significantly different between the irisin quartile groups of elderly male patients with hyperhomo-cysteinemia(P＜0.001);grip strength and step speed were significantly different between the irisin quartile groups of elderly female pa-tients with hyperhomocysteinemia(P=0.016,0.020).Multiple Logistic regression analysis showed that serum irisin(OR=0.951,95％CI:0.905-0.999)and percent body fat(OR=0.741,95％CI:0.641-0.857)were independent influences on the development of sarcopenia in elderly male patients with hyperhomocysteinemia(P＜0.05).Serum irisin(OR=0.942,95％CI:0.892-0.994),per-cent body fat(OR=0.698,95％CI:0.576-0.846),and platelet count(OR=1.013,95％CI:1.002-1.024)were independent influencing factors for sarcopenia in the elderly female patients with hyperhomocysteinemia(P＜0.05).Conclusion Elevated serum iri-sin and body fat percentage are independent protective factors against sarcopenia in elderly male and female patients with hyperhomocys-teinemia;elevated platelet count is an independent risk factor for sarcopenia in elderly female patients with hyperhomocysteinemia.

With the increasing prevalence of chronic kidney disease (CKD) and the progress of renal replacement therapy, there were more and more patients with long-term hemodialysis (hemodialysis). Cardiovascular diseases were the leading cause of death among hemodialysis patients, and a lot of these patients needed to be treated with percutaneous coronary intervention (PCI). However, hemodialysis patients had higher risks of both bleeding and thrombotic events, which made it difficulty to select drugs and their dosages for post-PCI dual antiplatelet therapy in clinical practice, and the impacts of hemodialysis on dual antiplatelet therapy were still unclear. We reported a 65-year-old male patient with CKD, who was on long-term hemodialysis treatment and underwent PCI for acute non-ST segment elevation myocardial infarction. The patient was given dual antiplatelet therapy with aspirin and clopidogrel after the procedure, and on the fourth day after PCI (14 hours after restarting hemodialysis), he developed subacute stent thrombosis due to clopidogrel resistance, which was resolved after revascularization. Based on the treatment experience in this patient and review of relevant literature, we proposed recommendations on management of dual antiplatelet therapy in long-term hemodialysis patients from 3 aspects: drug selection, clopidogrel dose adjustment, and hemodialysis management after PCI.