Objective:An isolated wireless electronic stethoscope was developed to solve the problem that doctors cannot auscultate in personal protective equipment（PPE）during the COVID-19 outbreak.Methods:The development adopted low-noise audio amplification，high-frequency sampling，high-precision analog-to-digital conversion，and stainless-steel unibody design to improve the audio quality. In order to solve the problem of difficulty in turning on the Bluetooth headsets after automatic power off when the doctors are wearing PPE，we customized the Bluetooth headsets without the setting of automatically power off.Results:The isolated wireless electronic stethoscope has been clinically applied in Huoshenshan hospital in Wuhan，GuangGu branch of Hubei Maternal and Child Healthcare Hospital，Shanghai Public Health Clinical Center and other hospitals，receiving good feedback from doctors at front line.Conclusion:The isolated wireless electronic stethoscope can meet the needs of auscultation when the doctors are wearing PPE.

Objective:An isolated wireless electronic stethoscope was developed to solve the problem that doctors cannot auscultate in personal protective equipment（PPE）during the COVID-19 outbreak.Methods:The development adopted low-noise audio amplification，high-frequency sampling，high-precision analog-to-digital conversion，and stainless-steel unibody design to improve the audio quality. In order to solve the problem of difficulty in turning on the Bluetooth headsets after automatic power off when the doctors are wearing PPE，we customized the Bluetooth headsets without the setting of automatically power off.Results:The isolated wireless electronic stethoscope has been clinically applied in Huoshenshan hospital in Wuhan，GuangGu branch of Hubei Maternal and Child Healthcare Hospital，Shanghai Public Health Clinical Center and other hospitals，receiving good feedback from doctors at front line.Conclusion:The isolated wireless electronic stethoscope can meet the needs of auscultation when the doctors are wearing PPE.