1.Effect of Metabolic Syndrome and Metabolic Abnormalities on Remission of Bipolar Disorder Inpatients: A Retrospective Chart Review Study
Suwan KIM ; Young Sup WOO ; Won-Seok CHOI ; Won-Myong BAHK
Mood and Emotion 2024;22(1):27-35
Background:
Associations between metabolic abnormalities and poor treatment outcomes in bipolar disorder (BD) have been reported. This study examined the influence of metabolic abnormalities on remission in Korean inpatients with BD.
Methods:
This study retrospectively reviewed the chart of 128 adult patients with BD who were hospitalized at a university hospital in Korea. The collected data included fasting plasma glucose, total cholesterol, triglycerides, and high-density lipoprotein levels at admission, as well as height, weight, and blood pressure measurements. The prevalence of metabolic abnormalities was compared between the remission (17-item Hamilton Depression Rating Scalescore of ≤7 and Young Mania Rating Scale score of <8) and nonremission groups.
Results:
Prevalence of hyperglycemia and hypertriglyceridemia significantly differed between the nonremission and remission groups. Multivariate analysis revealed hyperglycemia as the only significant risk factor for nonremission in subjects with mood and manic/hypomanic episodes.
Conclusion
The study findings reveal a negative effect of hyperglycemia on the treatment outcome of BD. Clinical attention to metabolic abnormalities, specifically insulin resistance and hyperglycemia, is recommended during early stages of the disease.
2.Effect of Metabolic Syndrome and Metabolic Abnormalities on Remission of Bipolar Disorder Inpatients: A Retrospective Chart Review Study
Suwan KIM ; Young Sup WOO ; Won-Seok CHOI ; Won-Myong BAHK
Mood and Emotion 2024;22(1):27-35
Background:
Associations between metabolic abnormalities and poor treatment outcomes in bipolar disorder (BD) have been reported. This study examined the influence of metabolic abnormalities on remission in Korean inpatients with BD.
Methods:
This study retrospectively reviewed the chart of 128 adult patients with BD who were hospitalized at a university hospital in Korea. The collected data included fasting plasma glucose, total cholesterol, triglycerides, and high-density lipoprotein levels at admission, as well as height, weight, and blood pressure measurements. The prevalence of metabolic abnormalities was compared between the remission (17-item Hamilton Depression Rating Scalescore of ≤7 and Young Mania Rating Scale score of <8) and nonremission groups.
Results:
Prevalence of hyperglycemia and hypertriglyceridemia significantly differed between the nonremission and remission groups. Multivariate analysis revealed hyperglycemia as the only significant risk factor for nonremission in subjects with mood and manic/hypomanic episodes.
Conclusion
The study findings reveal a negative effect of hyperglycemia on the treatment outcome of BD. Clinical attention to metabolic abnormalities, specifically insulin resistance and hyperglycemia, is recommended during early stages of the disease.
3.Effect of Metabolic Syndrome and Metabolic Abnormalities on Remission of Bipolar Disorder Inpatients: A Retrospective Chart Review Study
Suwan KIM ; Young Sup WOO ; Won-Seok CHOI ; Won-Myong BAHK
Mood and Emotion 2024;22(1):27-35
Background:
Associations between metabolic abnormalities and poor treatment outcomes in bipolar disorder (BD) have been reported. This study examined the influence of metabolic abnormalities on remission in Korean inpatients with BD.
Methods:
This study retrospectively reviewed the chart of 128 adult patients with BD who were hospitalized at a university hospital in Korea. The collected data included fasting plasma glucose, total cholesterol, triglycerides, and high-density lipoprotein levels at admission, as well as height, weight, and blood pressure measurements. The prevalence of metabolic abnormalities was compared between the remission (17-item Hamilton Depression Rating Scalescore of ≤7 and Young Mania Rating Scale score of <8) and nonremission groups.
Results:
Prevalence of hyperglycemia and hypertriglyceridemia significantly differed between the nonremission and remission groups. Multivariate analysis revealed hyperglycemia as the only significant risk factor for nonremission in subjects with mood and manic/hypomanic episodes.
Conclusion
The study findings reveal a negative effect of hyperglycemia on the treatment outcome of BD. Clinical attention to metabolic abnormalities, specifically insulin resistance and hyperglycemia, is recommended during early stages of the disease.
4.Effect of Metabolic Syndrome and Metabolic Abnormalities on Remission of Bipolar Disorder Inpatients: A Retrospective Chart Review Study
Suwan KIM ; Young Sup WOO ; Won-Seok CHOI ; Won-Myong BAHK
Mood and Emotion 2024;22(1):27-35
Background:
Associations between metabolic abnormalities and poor treatment outcomes in bipolar disorder (BD) have been reported. This study examined the influence of metabolic abnormalities on remission in Korean inpatients with BD.
Methods:
This study retrospectively reviewed the chart of 128 adult patients with BD who were hospitalized at a university hospital in Korea. The collected data included fasting plasma glucose, total cholesterol, triglycerides, and high-density lipoprotein levels at admission, as well as height, weight, and blood pressure measurements. The prevalence of metabolic abnormalities was compared between the remission (17-item Hamilton Depression Rating Scalescore of ≤7 and Young Mania Rating Scale score of <8) and nonremission groups.
Results:
Prevalence of hyperglycemia and hypertriglyceridemia significantly differed between the nonremission and remission groups. Multivariate analysis revealed hyperglycemia as the only significant risk factor for nonremission in subjects with mood and manic/hypomanic episodes.
Conclusion
The study findings reveal a negative effect of hyperglycemia on the treatment outcome of BD. Clinical attention to metabolic abnormalities, specifically insulin resistance and hyperglycemia, is recommended during early stages of the disease.
5.Effect of Metabolic Syndrome and Metabolic Abnormalities on Remission of Bipolar Disorder Inpatients: A Retrospective Chart Review Study
Suwan KIM ; Young Sup WOO ; Won-Seok CHOI ; Won-Myong BAHK
Mood and Emotion 2024;22(1):27-35
Background:
Associations between metabolic abnormalities and poor treatment outcomes in bipolar disorder (BD) have been reported. This study examined the influence of metabolic abnormalities on remission in Korean inpatients with BD.
Methods:
This study retrospectively reviewed the chart of 128 adult patients with BD who were hospitalized at a university hospital in Korea. The collected data included fasting plasma glucose, total cholesterol, triglycerides, and high-density lipoprotein levels at admission, as well as height, weight, and blood pressure measurements. The prevalence of metabolic abnormalities was compared between the remission (17-item Hamilton Depression Rating Scalescore of ≤7 and Young Mania Rating Scale score of <8) and nonremission groups.
Results:
Prevalence of hyperglycemia and hypertriglyceridemia significantly differed between the nonremission and remission groups. Multivariate analysis revealed hyperglycemia as the only significant risk factor for nonremission in subjects with mood and manic/hypomanic episodes.
Conclusion
The study findings reveal a negative effect of hyperglycemia on the treatment outcome of BD. Clinical attention to metabolic abnormalities, specifically insulin resistance and hyperglycemia, is recommended during early stages of the disease.
6.Sternoclavicular xanthogranulomatous osteomyelitis in a patient after kidney transplantation: a case report
Kiyoung CHOI ; Youngmin YOON ; Ran HONG ; Hyun Lee KIM ; Jong Hoon CHUNG ; Byung Chul SHIN
Clinical Transplantation and Research 2024;38(2):150-153
Xanthogranulomatous osteomyelitis (XO) is a rare chronic inflammatory bone disease characterized by the presence of cholesterol-laden foam macrophages, histiocytes, and plasma cells. We report the case of a 41-year-old man with end-stage renal disease who had undergone deceased donor kidney transplantation 4 years earlier. He presented with a chest wall mass that he had first identified 2 weeks prior to admission. Computed tomography revealed a periosseous heterogeneously enhancing soft tissue mass adjacent to the sternal end of the left clavicle, accompanied by irregular and destructive osteolytic lesions on the left side of the sternal manubrium. A total mass resection, which included partial clavicle and sternum removal, was performed. Pathological examination revealed foamy histiocytes along with numerous lymphoplasmacytic cells, confirming the diagnosis of XO. This case underscores the potential for XO to develop following kidney transplantation.
7.Differences in Pilon Fractures According to Ipsilateral Fibular Injury Patterns: A Clinical Computed Tomography-Based Mapping Study
Jae-Hwan LIM ; Jun-Young LEE ; Ba-Rom KIM ; Suenghwan JO ; Dong-Hyuk CHA ; Hyo-Jun LEE ; Gu-Hee JUNG
Clinics in Orthopedic Surgery 2023;15(3):358-366
Background:
Preoperative verification of fracture morphology is essential for determining the definitive fixation strategy in the management of a pilon fracture. This study aimed to determine the correlation between fibular injury patterns and fracture morphologies and introduce clinical implications.
Methods:
Computed tomography scans of 96 pilon fractures were retrospectively analyzed and divided into three types: intact fibula, simple fracture, and multifragment fracture. The principal fracture line and comminution zones were illustrated on a plafond template and diagrammatized on a 6 × 6 grid using PowerPoint software as fracture mapping. Correlations between fibular injury patterns and fracture morphologies, including comminution zones and principal fracture lines, were analyzed.
Results:
The thickest comminution zone was most often located in the anterolateral quadrant. According to fibular injury patterns, the comminution zone of the multifragment group was placed two grids more lateral than that of other groups. Lateral exits of the principal fracture line in the multifragment group were much more concentrated within the fibular incisura.
Conclusions
In pilon fractures, a more complex fibular fracture pattern was related to the valgus position. Moreover, the articular fracture pattern of pilon fractures differed according to coronal angulation and fibular fracture pattern. These differences should influence the operative approach and placement of the plate.
8.Educational Applications of Psychotherapy for the Medical Students: Development of Psychotherapy Education Model
Hyun Young OH ; Yong Chon PARK ; Seon-Cheol PARK ; Eun Kyung KIM
Journal of Korean Neuropsychiatric Association 2021;60(1):86-95
Objectives:
We have been providing psychotherapy training for medical students enrolled in the course of ‘Clinical Practice.’ The aim of this study is to introduce the psychotherapy education developed in this process, conceptualize objective education methods, and check the impact of educational applications of psychotherapy for medical students.
Methods:
Psychotherapy was applied to the medical students during their clerkship in psychiatry. 221 medical students participated in this program from 2017–2019, which consisted of 2–3 people in a group. One was in charge of clients, and the other was an observer. Their clerkship was based on psychodynamic psychotherapy, especially Taopsychotherapy. Before and after the practice, participants completed a self-reporting questionnaire about ego identity, self-concealment, and professional help-seeking attitudes. Statistical analysis using a two-way repeated measure analysis of variance was conducted.
Results:
Participants learned of the nuclear feelings associated with the current problem and were surprised to find a connection with past experiences, but accepted the connection. Selfidentity decreased in the client role students (p=0.001), and professional help-seeking attitude increased in both client and observer role students (p=0.001).
Conclusion
In the general course of psychotherapy, patients are reminded of their first interpersonal relationships, like parents, and in the beginning, they only think of positive aspects under repressed emotions. However, they gradually recalled negative emotions. The above practical course featured this same pattern. As they recognized negative emotions that were repressed, self-identity decreased in client role students.

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