Acute ischemic stroke poses a substantial burden on families and society with its high inci-dence,mortality,and disability rates.As the population ages,the number of elderly patients with acute ische-mic stroke has risen significantly.However,clinicians face considerable challenges in selecting optimal treat-ment strategies due to the clinical characteristics of this geriatric population.This article reviewed the efficacy and safety of mechanical thrombectomy in elderly patients with acute ischemic stroke,aiming to offer some suggestions for personalized therapeutic decision-making in these patients.