Objective To retrospectively assess the diagnostic value of nuchal translucency (NT) thickness and facial profile ultrasonic markers [including frontomaxillary facial (FMF) angle,and the ratio of prenasal thickness to nasal bone length (PT/NBL)] for trisomy 21 syndrome in first-trimester fetuses.Methods Ultrasonograhic images of 35 fetuses with trisomy 21 syndrome and 70 gestational age matched normal fetuses were analyzed in first-trimester.NT,FMF angle and the PT/NBL ratio were measured retrospectively in stored images from digital database between January 2012 and December 2015.The diagnostic value of NT,FMF angle and PT/NBL ratio were compared with different combinations.Results (1) The mean NT was significantly higher in the trisomy 21 group than that in controls (t =7.401,P =0.00).The NT above 2.5mm was observed in 20 trisomy 21 fetuses (57.1％) and in 3 normal fetuses (4.3％).(2) The mean FMF angle was significantly higher in the trisomy 21 group than that in controls (t =-5.283,P =0.00).The FMF angle above the 95th percentile (93.6°) was observed in 13 trisomy 21 fetuses (37.1％) and in 1 normal fetus (1.4％).(3) The mean PT/NBL ratio was significantly higher in the trisomy 21 group than that in controls (t =-7.826,P =0.00).The PT/NBL ratio above the 95th percentile (0.93) was observed in 19 trisomy 21 fetuses (54.3％) and in 4 normal fetuses (5.7％).(4) The sensitivity and Youden index for trisomy 21 increased gradually,which were 57.1 ％ and 0.528 by using NT,and 74.3％ and 0.686 by using NT and FMF angle,and 91.4％ and 0.828 by using NT,FMF angle and PT/NBL ratio.There were significant differences in the detection rates of trisomy 21 among the three strategies,while the diagnostic specificity of the three strategies were more than 90％.Conclusions The three parameters are significantly increased in trisomy 21 fetus in first-trimester.First,increased NT was most commonly detected,followed by increased PT/NBL ratio,and increased FMF angle again.Detection rates for trisomy 21 fetuses in first-trimester by ultrasound screening can be significantly improved if combination of all three parameters rather than just one parameter are performed.

Objective To observe the effects of HBO combined with comprehensive drug treatment on 58 cases of acute face neuritis.Methods In accordance with the case selection criteria,116 case of acute face neuritis were chosen for the study.With the knowledge and consent of the patients and following the signing of the letter of agreement and with the agreement of the Hospital Ethic Committee,1 16 patients were divided into 2 groups:the experimental group and the control group,each consisting of 58 patients.The patients in the control group were only treated with regular drug treatment,while the patients in the experimental group were offered HBO treatment and regular drug treatment as well.They were all treated for a succession of 3 weeks and observation was made on the therapeutic results of both groups.Results After 3 weeks of treatment,facial nerve function scores for the patients of both groups all increased when compared with those before treatment,with statistical significance (P ＜ 0.01).Scores for the patients in the experimental group were significantly higher than those for the patients of the control group (P ＜ 0.05).Conclusions Comprehensive HBO treatment seemed to produce significant effects in the treatment of acute face neuritis.

Objective To observe the effects of HBO combined with comprehensive drug treatment on 58 cases of acute face neuritis.Methods In accordance with the case selection criteria,116 case of acute face neuritis were chosen for the study.With the knowledge and consent of the patients and following the signing of the letter of agreement and with the agreement of the Hospital Ethic Committee,1 16 patients were divided into 2 groups:the experimental group and the control group,each consisting of 58 patients.The patients in the control group were only treated with regular drug treatment,while the patients in the experimental group were offered HBO treatment and regular drug treatment as well.They were all treated for a succession of 3 weeks and observation was made on the therapeutic results of both groups.Results After 3 weeks of treatment,facial nerve function scores for the patients of both groups all increased when compared with those before treatment,with statistical significance (P ＜ 0.01).Scores for the patients in the experimental group were significantly higher than those for the patients of the control group (P ＜ 0.05).Conclusions Comprehensive HBO treatment seemed to produce significant effects in the treatment of acute face neuritis.

Objective To compare high-frequency ultrasonography and MRI in diagnosis of medial patellofemoral ligament (MPFL) injury after acute lateral traumatic patellar dislocation(LTPD).Methods According to surgical data of 35 patients with acute LTPD,the incidence and sites of MPFL injury were analyzed.Further,based on high frequency ultrasonography and MRI data,the sensitivity,specificity and accuracy of high-frequency ultrasonography and MRI in different MPFL injuries were analyzed and compared.Results Among 35 patients,there were 21 cases with complete MPFL tear and 14 cases with partial MPFL tear.Tear of MPFL at the femoral attachment in 19 cases,at the patellar attachment in 15 cases,and at the mid-substance in 1 case.The sensitivity,specificity,accuracy of high-frequency ultrasonography diagnosis were 78.6％,95.2％,88.6％ respectively on partial MPFL tear and 95.2％,78.6 ％,88.6 ％ respectively on complete MPFL tear.The sensitivity,specificity,accuracy of MRI diagnosis were 85.7％,90.5％,88.6％ respectively on partial MPFL tear and 90.5％,85.7％,88.6％ respectively on complete MPFL tear.There were no significant difference between high-frequency ultrasonography and MRI in diagnosis of partial and complete MPFL injury (x2 =0.243,0.267; P =0.622,0.599).Conclusions MPFL formoral attachment is most vulnerable to damage,followed by patellar attachment.High-frequency ultrasonography,as well as MRI,can be used clearly to diagnose MPFL injury and accurately classify the damage,and it is also an easy,reliable,rapid method,which can be applied routinely to diagnose MPFL injury after actue LTPD.