1.Generative AI–assisted “Gratitude Song” as Legacy-making in End-of-life Care: A Case Report
Suguru MATSUZAKA ; Emi HARADA ; Hideyuki KASHIWAGI
Palliative Care Research 2025;20(4):259-263
Objective: To report a single-case legacy-making intervention in which generative AI transformed gratitude messages into a song for a terminally ill patient. Methods: A 68-year-old woman with advanced ovarian cancer underwent a 30-minute semi-structured interview to elicit family messages and musical preferences. Lyrics and musical style were generated with AI, and six vocal tracks were produced; one was selected with the patient. Results: The process was feasible within 90 minutes, accepted by the patient and family, and caused no apparent adverse events. The patient stated that “my message took shape,” showing enhanced life review, and the song’s use at her funeral provided comfort for the family. Ethics: Personal identifiers were excluded, and data retention was disabled. Conclusions: A generative AI “Gratitude Song” enabled visualization and sonification of messages despite physical limitations, suggesting a potential option for spiritual care.
2.A Giant Cranial Sebaceous Adenocarcinoma Which Responded to Multi-modal Therapy Including Palliative Radiotherapy
Suguru MATSUZAKA ; Kiyofumi OYA ; Katsuyuki KATAYAMA ; Mina MATSUMOTO ; Rie SASAKI ; Ivor CAMMACK ; Hideyuki KASHIWAGI
Palliative Care Research 2021;16(1):67-72
Introduction: We report a case in which multidisciplinary treatment including palliative radiotherapy reduced the size, exudate production and symptoms of a sebaceous carcinoma that had been neglected and allowed to form into a large destructive lesion. Case: A 48-year-old unemployed man who lived alone, was estranged from his family and socially isolated presented with a cranial tumor which had been present for three years. He did seek medical attention on one occasion. But a definitive diagnosis was not made, and he neglected to seek further treatment. The tumor became very large, painful and began to ooze exudate, and the patient became unwell with difficulty mobilizing. He was transported to the hospital by ambulance. The tumor was centered on the vertex of the scalp and had a maximum diameter of 30 cm. It was diagnosed pathologically as a sebaceous carcinoma and was inoperable. The tumor was treated with palliative radiotherapy, a total dose of 27 Gy / 9 Fr, causing it to shrink by approximately 30% and markedly reduced the rate of exudate production. His condition improved markedly and he was able to go out on leave. Discussion: This case highlights the management and clinical course of an uncommon and large cranial sebaceous carcinoma.


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