1.Metagenomic Next-Generation Sequencing-Assisted Diagnosis of Japanese Spotted Fever: Report of One Case.
Yong-Chun RUAN ; Yi-Qing ZHOU ; Hai-Wang ZHANG ; Jie ZHOU ; Jin-Nan DUAN ; Xiao-Jing ZHANG ; L I MING-HUI
Acta Academiae Medicinae Sinicae 2025;47(1):146-149
Japanese spotted fever(JSF)is an infectious disease caused by Rickettsia japonica,with nonspecific clinical symptoms and a high risk of misdiagnosis.We reported a case of JSF,in which Rickettsia japonica was detected in blood cells by metagenomic next-generation sequencing.The patient recovered after treatment with doxycycline.This report provides a reference for the clinical diagnosis and treatment of JSF.
Humans
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High-Throughput Nucleotide Sequencing
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Metagenomics
;
Rickettsia/isolation & purification*
;
Spotted Fever Group Rickettsiosis/microbiology*

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