1.Progress in the application of exosomes in the diagnosis and treatment of diabetic retinopathy
Songguo DONG ; Chunyan SONG ; Xiaofeng HOU ; Weihua YANG ; Yun WANG
International Eye Science 2025;25(2):235-241
Exosomes are ubiquitous in all types of body fluids, exhibiting a high degree of abundance and diversity. Given their distinctive structure and function, exosomes are involved in a range of life activities, including intercellular communication, material transport, and immune regulation. An increasing number of studies have identified exosomes as a source of diagnostic markers for diabetic retinopathy. Furthermore, exosomes represent a novel avenue for therapeutic intervention, with promising clinical applications. This paper examines the diagnostic and therapeutic mechanisms of exosomes in diabetic retinopathy, reviews the advancements in exosomes-based diagnostics and therapeutics for diabetic retinopathy, and aims to enhance the precision and efficiency of clinical diagnosis and treatment of diabetic retinopathy.
2.Biallelic mutations in CDC20 cause female infertility characterized by abnormalities in oocyte maturation and early embryonic development.
Lin ZHAO ; Songguo XUE ; Zhongyuan YAO ; Juanzi SHI ; Biaobang CHEN ; Ling WU ; Lihua SUN ; Yao XU ; Zheng YAN ; Bin LI ; Xiaoyan MAO ; Jing FU ; Zhihua ZHANG ; Jian MU ; Wenjing WANG ; Jing DU ; Shuai LIU ; Jie DONG ; Weijie WANG ; Qiaoli LI ; Lin HE ; Li JIN ; Xiaozhen LIANG ; Yanping KUANG ; Xiaoxi SUN ; Lei WANG ; Qing SANG
Protein & Cell 2020;11(12):921-927

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