OBJECTIVES

The increasing prevalence of Kawasaki disease in Southeast Asia (SEA) and its potential relation with Coronavirus Disease 2019 (COVID-19) infection resulted in heightened interest in KD in the region, thus, this paper aimed to determine the trend and the socioeconomic facilitators of scientific productivity of KD research within the region. Specifically, this article determined the number of publication and citations related to KD per country, institution, and journal. We also explored the networks of countries within the region to the rest of the world and the keywords mostly associated with KD research in the region. Lastly, correlation of these bibliometric indices with socioeconomic factors in the region was analyzed.

METHODS

A literature search of KD papers in SEA was performed using Scopus database. We obtained bibliographic data from the available literature and visualized network of existing collaborations and keywords using VOSviewer software.

RESULTS

A total of 196 papers were included in the study. Bibliometric analysis showed a rising trend in publication within the region, most of which were from institutions in Singapore and Thailand. The most common topics on KD studies included clinical features, complications, treatment, and comorbidities. 

Country characteristics such as gross domestic product (GDP) per capita, research and development (R&D) expenditure (% GDP), and number of physician and R&D researchers were positively correlated with bibliometric indices of KD research in SEA. Moreover, number of international linkages was significantly associated with KD research productivity in the region. 

CONCLUSION

In summary, we showed an increasing trend of KD research in SEA. Funding allocation and capacity building are necessary to strengthen research productivity within the region.

Asia ; Asia, Southeastern ; Bibliometrics ; Capacity Building ; Coronavirus ; Covid-19 ; Database ; Disease ; Efficiency ; Gross Domestic Product ; Guanosine Diphosphate ; Infection ; Infections ; Literature ; Mucocutaneous Lymph Node Syndrome ; Paper ; Physicians ; Prevalence ; Publications ; Research ; Research Personnel ; Rest ; Singapore ; Socioeconomic Factors ; Software ; Thailand ; Therapeutics

Introduction: Phase angle (PhA) derived from bioelectrical impedance analysis reflects cellular integrity and has emerged as a potential marker of metabolic health. Its role in detecting early physiological changes during lifestyle intervention remains underexplored in workplace obesity programmes. Methodology: This longitudinal study included 30 adults with complete paired measurements enrolled in a 12-month workplace lifestyle programme. Body composition was assessed using multifrequency bioelectrical impedance analysis. Measurements included whole-body PhA, body cell mass (BCM), skeletal muscle index (SMI), and extracellular water to total body water ratio. Paired comparisons and correlation analyses were performed. Results: Mean PhA increased modestly from 5.59 ± 0.70° to 5.67 ± 0.69°, although this did not reach statistical significance (p = 0.17). Changes in PhA were not significantly associated with changes in BCM (r = −0.03, p = 0.89). However, baseline PhA demonstrated a moderate positive association with SMI (r ≈ 0.51, p <0.01), suggesting a link between cellular integrity and muscle status. Individual trajectories revealed heterogeneous responses despite minimal weight change. Conclusion Whole-body phase angle provides insight into cellular health beyond conventional anthropometric measures. While short-term changes were modest, PhA may serve as a clinically useful adjunct for monitoring physiological response in obesity management programmes.
Workplace

Introduction: Obesity is a chronic disease characterized by complex alterations in body composition and metabolic health. Traditional reliance on body weight may overlook important physiological adaptations during lifestyle intervention. Methodology: A cohort of 99 participants at programme entry underwent body composition assessment using bioelectrical impedance analysis. Parameters included percent body fat (PBF), visceral fat area (VFA), skeletal muscle index (SMI), and phase angle (PhA). Correlation analyses were performed to explore relationships between adiposity, muscle mass, and cellular health. Results: Participants demonstrated elevated adiposity (PBF 38.9 ± 8.9%; VFA 142.9 ± 56.1 cm²). PhA was inversely associated with VFA (r ≈ −0.23, p <0.05) and positively associated with SMI (r ≈ 0.49, p <0.001). Notably, a subset of overweight individuals exhibited relatively preserved PhA, indicating heterogeneity in metabolic health despite similar adiposity levels. Conclusion Body composition and PhA provide complementary insights into metabolic health beyond body weight. These findings support the role of bioimpedance-derived parameters in identifying metabolic heterogeneity and guiding personalized obesity management.
Body Composition ; Body Weight ; Workplace ; Obesity

Rabies remains a persistent public health issue in the Philippines, despite the existence of national and local policies and programs aimed at addressing its eradication. The viral disease, which elicits fatality yet is preventable, disproportionately affects rural areas, especially geographically isolated and disadvantaged area due to the junction of socio-cultural and technical challenges. This commentary article explores the myriad of barriers to rabies prevention and control, including poverty, cultural beliefs, limited health literacy, health delivery, and access inequity. However, the implementation of Rabies Act of 2007, which mandates mass vaccination, education, and the establishment of Animal Bite Treatment Centers (ABTCs), has gaps in the implementation that compromises the program’s sustainability and effectiveness. Deep-rooted cultural practices and beliefs delay or, more so replace evidence-informed medical practices, while geographic isolation and underfunded healthcare facilities hinder optimal provision of care. Moreover, interagency coordination and fragmented reporting surveillance systems further complicate effective rabies control. To address the gaps, this paper advocates for a culturally tailored and community-centered One Health approach that addresses both social and technical aspects of rabies prevention. Important recommendations include decentralizing ABTCs, sustaining vaccination programs with local government support and funding, integrating rabies education into schools and community outreach, and intensifying through multisectoral collaboration both government and nongovernment institutions. Achieving a rabies-free country requires not only biomedical interventions but also a holistic approach – equitable access to healthcare, trust building in communities, and long-term political commitment. In this manner, regardless of location and socioeconomic status, it ensures that this viral disease will be controlled and prevented.

Human ; Philippines ; Social Class ; Rabies ; Virus Diseases ; Mass Vaccination

Congenital musculoskeletal and limb deformities (CMLD) seriously affect the physical and mental health of patients, and pose great challenges to healthcare systems worldwide. We explored the specific situation and changes of incidence, prevalence, disability-adjusted life years rates, and mortality of CMLD in under-5 children from 1990 to 2021 in different groups, including different regions, periods, genders and socio-demographic indices (SDI), through corresponding analytical models. Overall, the global disease burden of CMLD in under-5 children has decreased from 1990 to 2021. The disease burden of CMLD in under-5 children varied significantly among different regions and countries, and there was a strong correlation between the corresponding burden of disease and the level of SDI. In addition, cross-country inequality analysis showed that while absolute inequalities in the disease burden of CMLD in under-5 children have improved, relative inequalities have worsened. It is essential to reduce the global health impact of CMLD by implementing targeted interventions to improve health care in underdeveloped areas.
Humans ; Global Burden of Disease/trends* ; Child, Preschool ; Global Health/statistics & numerical data* ; Infant ; Male ; Prevalence ; Limb Deformities, Congenital/mortality* ; Musculoskeletal Abnormalities/mortality* ; Female ; Disability-Adjusted Life Years ; Incidence ; Infant, Newborn ; Cost of Illness ; Socioeconomic Factors

OBJECTIVE: This study aimed to identify high-risk areas for type 2 diabetes mellitus (T2DM) mortality to provide relevant evidence for interventions in emerging economies. METHODS: Empirical Bayesian Kriging and a discrete Poisson space-time scan statistic were applied to identify the spatiotemporal clusters of T2DM mortality. The relationships between economic factors, air pollutants, and the mortality risk of T2DM were assessed using regression analysis and the Poisson Log-linear Model. RESULTS: A coastal district in East Guangdong, China, had the highest risk (Relative Risk [RR] = 4.58, P < 0.01), followed by the 10 coastal districts/counties in West Guangdong, China (RR = 2.88, P < 0.01). The coastal county in the Pearl River Delta, China (RR = 2.24, P < 0.01), had the third-highest risk. The remaining risk areas were two coastal counties in East Guangdong, 16 districts/counties in the Pearl River Delta, and two counties in North Guangdong, China. Mortality due to T2DM was associated with gross domestic product per capita (GDP per capita). In pilot assessments, T2DM mortality was significantly associated with carbon monoxide. CONCLUSION High mortality from T2DM occurred in the coastal areas of East and West Guangdong, especially where the economy was progressing towards the upper middle-income level.
Diabetes Mellitus, Type 2/epidemiology* ; China/epidemiology* ; Humans ; Risk Factors ; Spatio-Temporal Analysis ; Air Pollutants/analysis* ; Socioeconomic Factors ; Bayes Theorem ; Female ; Male ; Middle Aged

OBJECTIVE: To investigate the spatiotemporal patterns and socioeconomic factors influencing the incidence of tuberculosis (TB) in the Guangdong Province between 2010 and 2019. METHOD: Spatial and temporal variations in TB incidence were mapped using heat maps and hierarchical clustering. Socioenvironmental influencing factors were evaluated using a Bayesian spatiotemporal conditional autoregressive (ST-CAR) model. RESULTS: Annual incidence of TB in Guangdong decreased from 91.85/100,000 in 2010 to 53.06/100,000 in 2019. Spatial hotspots were found in northeastern Guangdong, particularly in Heyuan, Shanwei, and Shantou, while Shenzhen, Dongguan, and Foshan had the lowest rates in the Pearl River Delta. The ST-CAR model showed that the TB risk was lower with higher per capita Gross Domestic Product (GDP) [Relative Risk ( RR), 0.91; 95% Confidence Interval ( CI): 0.86-0.98], more the ratio of licensed physicians and physician ( RR, 0.94; 95% CI: 0.90-0.98), and higher per capita public expenditure ( RR, 0.94; 95% CI: 0.90-0.97), with a marginal effect of population density ( RR, 0.86; 95% CI: 0.86-1.00). CONCLUSION The incidence of TB in Guangdong varies spatially and temporally. Areas with poor economic conditions and insufficient healthcare resources are at an increased risk of TB infection. Strategies focusing on equitable health resource distribution and economic development are the key to TB control.
Humans ; China/epidemiology* ; Incidence ; Bayes Theorem ; Spatio-Temporal Analysis ; Tuberculosis/epidemiology* ; Socioeconomic Factors

BACKGROUND

Ahigh-quality measurement tool is essential to accurately assess the innovative teaching strategies in health professions education. The Blended Teaching Assessment Tool (BTAT) aims to evaluate quality blended teaching or instructional delivery in Philippine health science programs. However, there is a lack of studies examining students' cognitive processes to support the validity of questionnaires.

METHODOLOGY

Cognitive interviewing (CI) was employed to determine whether students interpreted and responded to the items correctly. Content analysis was done using Tourangeau's Cognitive framework. Four CIs were conducted by an expert moderator and note-taker with a total of 8 health science students (2 groups with 3 members, and 2 one-on-one interview) for around 1 to 2 hours via Zoom following a retroactive approach with verbal and spontaneous probing, guided by a semi-structured interview questionnaire.

RESULTS

Various issues related to comprehension, retrieval, judgment, and response were identified, leading to significant revisions of the tool from 82 items across 8 dimensions to 53 items across 5 dimensions. The challenges included unfamiliar terminology, ambiguous phrasing, complex statements, inconsistencies and irrelevance to students' real-life experiences. These findings emphasize the importance of students' feedback in enhancing the validity and reliability of assessment tools.

CONCLUSION

The Cognitive Interview identified crucial issues in comprehension, retrieval, judgment, and response, making it essential for developing the Blended Teaching Assessment Tool and ensuring valid responses on the quality of blended teaching and learning delivery.

Health Occupations ; Education ; Teaching

BACKGROUND

Youth with disabilities (YWDs) in countries like the Philippines face substantial employment barriers. While school-to-work (STW) transition programs and strong family support are crucial for their success, family involvement in planning is often insufficient.

OBJECTIVES

This study aims to explore the perspectives of families of YWDs on STW transition in the Philippines and the differences in perspectives among families from varying socioeconomic backgrounds.

METHODS

This exploratory-descriptive qualitative study utilized semi-structured interviews with seven primary caregivers of YWDs in Metro Manila, representing diverse socioeconomic backgrounds. Thematic analysis was employed.

RESULTS

Three key themes emerged. First, families underscored the value of education in shaping STW transition outcomes, emphasizing its role in building literacy and practical life skills and highlighting the need for improved school support and educator training. Second, significant challenges in accessing support and transition services were reported, with financial constraints in obtaining government aid being a major hurdle regardless of socioeconomic status. Finally, caregivers stressed the family's vital role in transitioning YWDs for adulthood and work, particularly in fostering independence, nurturing strengths, and developing relevant skills for future employment.

CONCLUSION

This study explored the Filipino families' shared perspectives on STW transition, highlighting the value of education, challenges in accessing support, and the family's role in the transition process. It emphasized the need for accessible and inclusive transition services addressing socioeconomic and cultural factors affecting YWDs and their families. Enhanced stakeholder collaboration is crucial in creating comprehensive and culturally relevant STW services that promote successful workforce integration of YWDs.

Human ; Employment, Supported ; Occupations ; Vocation

Human ; Health Occupations ; Education ; Philippines