Plastics are widely used in all areas of human life,providing convenience while also causing serious en-vironmental pollution problems.Microplastic pollution is one of its derivative problems.Microplastics are plastic parti-cles with a diameter of less than 5 mm.They are currently widely present in the environment,so humans are at considera-ble risk of exposure to microplastics.Humans are mainly exposed to microplastics through the respiratory tract,digestive tract and skin.When exposed to a large number of microplastics,some of them will enter the body and be transported throughout the body via the bloodstream,accumulating in multiple tissues and organs.A significant amount of microplas-tics has also been detected in the cardiovascular system.This paper systematically describes human exposure to and dam-age by microplastics,highlighting the distribution and pathological damage of microplastics in the cardiovascular system.The pathological mechanisms of cardiovascular damage caused by microplastics are analyzed,and relevant clinical research progress is followed.This paper aims to evaluate the pathological risk of microplastics from the perspective of cardiovascu-lar damage,and provide a basis for disease prevention and scientific prevention and control of microplastic pollution.

Plastics are widely used in all areas of human life,providing convenience while also causing serious en-vironmental pollution problems.Microplastic pollution is one of its derivative problems.Microplastics are plastic parti-cles with a diameter of less than 5 mm.They are currently widely present in the environment,so humans are at considera-ble risk of exposure to microplastics.Humans are mainly exposed to microplastics through the respiratory tract,digestive tract and skin.When exposed to a large number of microplastics,some of them will enter the body and be transported throughout the body via the bloodstream,accumulating in multiple tissues and organs.A significant amount of microplas-tics has also been detected in the cardiovascular system.This paper systematically describes human exposure to and dam-age by microplastics,highlighting the distribution and pathological damage of microplastics in the cardiovascular system.The pathological mechanisms of cardiovascular damage caused by microplastics are analyzed,and relevant clinical research progress is followed.This paper aims to evaluate the pathological risk of microplastics from the perspective of cardiovascu-lar damage,and provide a basis for disease prevention and scientific prevention and control of microplastic pollution.