Objective To analyze the current promotion status of professional titles of healthcare-associated infec-tion(HAI)management full-time professionals in medical institutions in Anhui Province.Methods A cross-sec-tional survey was designed.An electronic questionnaire survey was conducted among HAI management full-time professionals from all levels of medical institutions in 16 cities in Anhui Province by Anhui Province HAI Manage-ment Quality Control Center,and the data were analyzed.Results A total of 815 HAI management full-time pro-fessionals participated in the survey.78.16％of the professionals were with nursing background;25.89％had mas-ter's degree and higher;55.95％held an intermediate-level professional titles;49.45％engaged in HAI manage-ment for less than 5 years;most professionals with advanced title were from tertiary medical institutions.There were significant differences in the pursuing route of professional title promotion among HAI management full-time professionals with different professional backgrounds:91.94％of clinical medical professionals chose the medical promotion route;96.55％of nursing professionals chose the nursing promotion route;75.41％of public health pro-fessionals chose the medical promotion route;84.61％of laboratory professionals and 50.00％of pharmacy profe-ssionals chose the medical technician promotion route.43.31％of HAI management full-time professionals were generally satisfied with the current status of professional title promotion,only 5.65％being very satisfied.The main cause why HAI management full-time professionals were dissatisfied with professional title promotion was"current professional title promotion evaluation standards",accounting for 45.60％.There was a statistically signi-ficant difference in the evaluation on the difficulty in promoting to the next level of professional title among full-time professionals with different professional titles(P＜0.001).The higher the professional title,the more difficult it was to be promoted to the next level.48.22％of HAI management full-time professionals thought the difficulties in pro-moting their professional titles was due to"the lack of professional and technical titles in HAI management",fo-llowed by"low promotion rates"(10.43％)and"weak competitiveness in promotion based on their original posi-tions"(9.69％).Conclusion Professional title promotion route for HAI management full-time professionals in An-hui Province depends on their original professional fields,and promotion is generally difficult,especially to senior professional titles.It is urgent to establish an independent technical professional title series for HAI management as well as a matched evaluation and appointment mechanism to stabilize the talent team.

Objective To analyze the current promotion status of professional titles of healthcare-associated infec-tion(HAI)management full-time professionals in medical institutions in Anhui Province.Methods A cross-sec-tional survey was designed.An electronic questionnaire survey was conducted among HAI management full-time professionals from all levels of medical institutions in 16 cities in Anhui Province by Anhui Province HAI Manage-ment Quality Control Center,and the data were analyzed.Results A total of 815 HAI management full-time pro-fessionals participated in the survey.78.16％of the professionals were with nursing background;25.89％had mas-ter's degree and higher;55.95％held an intermediate-level professional titles;49.45％engaged in HAI manage-ment for less than 5 years;most professionals with advanced title were from tertiary medical institutions.There were significant differences in the pursuing route of professional title promotion among HAI management full-time professionals with different professional backgrounds:91.94％of clinical medical professionals chose the medical promotion route;96.55％of nursing professionals chose the nursing promotion route;75.41％of public health pro-fessionals chose the medical promotion route;84.61％of laboratory professionals and 50.00％of pharmacy profe-ssionals chose the medical technician promotion route.43.31％of HAI management full-time professionals were generally satisfied with the current status of professional title promotion,only 5.65％being very satisfied.The main cause why HAI management full-time professionals were dissatisfied with professional title promotion was"current professional title promotion evaluation standards",accounting for 45.60％.There was a statistically signi-ficant difference in the evaluation on the difficulty in promoting to the next level of professional title among full-time professionals with different professional titles(P＜0.001).The higher the professional title,the more difficult it was to be promoted to the next level.48.22％of HAI management full-time professionals thought the difficulties in pro-moting their professional titles was due to"the lack of professional and technical titles in HAI management",fo-llowed by"low promotion rates"(10.43％)and"weak competitiveness in promotion based on their original posi-tions"(9.69％).Conclusion Professional title promotion route for HAI management full-time professionals in An-hui Province depends on their original professional fields,and promotion is generally difficult,especially to senior professional titles.It is urgent to establish an independent technical professional title series for HAI management as well as a matched evaluation and appointment mechanism to stabilize the talent team.

Objective To evaluate the diagnostic value of seven autoantibodies in the differential diagnosis of lung cancer patients. Methods The serum levels of seven autoantibodies p53, PGP9.5, SOX2, GAGE7, GBU4-5, MAGEA1 and CAGE were detected by ELISA in 122 subjects, which include 65 extrapulmonary tumors, 20 benign lung diseases, 3 small cell lung cancers, 20 physical examination subjects and 14 non-small cell lung cancers. Subsequently, the results were statistically analyzed by SPSS. Results The subjects were divided into five sub-groups, included extrapulmonary tumors, benign pulmonary lesions, small cell lung cancer, physical examination and non-small cell lung cancer subgroup. p53, SOX2, GBU4-5 and MAGEA1 in small cell cancer subgroup had significantly higher expression levels. Subjects were categorized differently using a ROC curve for statistical analy-sis. The results showed that p53 (AUC=0.664, P＜0.05) was significantly higher in lung cancer group than an-other group. GBU4-5 (AUC=0.639, P＜0.05) and the combination of the seven indicators (AUC=0.635,P＜0.05) had a certain diagnostic value for differential diagnosis of the non-malignant tumor group and the tumor group. MAGEA1, CAGE, PGP9.5, SOX2 and the combination of the seven indexes(AUC＞0.8,P＜0.05)had a high value in the differential diagnosis of small cell lung cancer group and another group. MAGEA1 ( AUC =0.333,P＜0.05) had some value in the differential diagnosis of the physical examination group and another group. p53 (AUC=0.33), PGP9.5 (AUC=0.355), GBU4-5(AUC=0.280),CAGE(AUC=0.341) and seven indi-cators combined detection( AUC =0.731 ) had certain value in the differential diagnosis of benign lung diseases group and another group. Conclusion According to the different groups, the detection of seven autoantibodies and their combined detection have a certain value for differential diagnosis of lung cancer.