Objective To explore the values of transvaginal ultrasound combined with abdominal ultrasound in diagnosis of patients with early ectopic pregnancy.Methods A total of 120 patients with ectopic pregnancy were selected and divided into two groups,60 cases in each group.The control group was treated with transvaginal ultrasound,and the experimental group was treated with transvaginal ultrasound and abdominal ultrasound.The diagnostic accuracy was compared between the two groups.Results In the detection of pelvic effusion,mass,germ,pregnancy sac,the experimental group was significantly higher than the control group (P ＜ 0.05).The positive rate of the experimental group was significantly higher than the control group (P ＜ 0.05).Conclusion Both transvaginal ultrasound and abdominal ultrasound have advantages and disadvantages.The combination of the two methods can obviously increase the positive rate of diagnosis of ectopic pregnancy and reduce the incidence of misdiagnosis and missed diagnosis.

Objective To explore the values of transvaginal ultrasound combined with abdominal ultrasound in diagnosis of patients with early ectopic pregnancy.Methods A total of 120 patients with ectopic pregnancy were selected and divided into two groups,60 cases in each group.The control group was treated with transvaginal ultrasound,and the experimental group was treated with transvaginal ultrasound and abdominal ultrasound.The diagnostic accuracy was compared between the two groups.Results In the detection of pelvic effusion,mass,germ,pregnancy sac,the experimental group was significantly higher than the control group (P ＜ 0.05).The positive rate of the experimental group was significantly higher than the control group (P ＜ 0.05).Conclusion Both transvaginal ultrasound and abdominal ultrasound have advantages and disadvantages.The combination of the two methods can obviously increase the positive rate of diagnosis of ectopic pregnancy and reduce the incidence of misdiagnosis and missed diagnosis.

Objective To study the therapeutic window of rapamycin(RPM) concentration in primary recipients of renal transplantation. Methods An open label, multi center study was performed. One hundred primary renal allograft recipients with cadaveric donors were enrolled from 4 transplantation centers in China. The immunosuppressive regimen was triple therapy,i.e.RPM combined with CsA and steroid. A loading dose of RPM 6 mg/d was administered within 48 hours after transplantation, then a maintaining dose of 2 mg/d was administered. The whole blood concentration of RPM was measured by HPLC method. Results The whole blood concentration of RPM in this group was (6.65?2.75)ng/ml, the 10th and 90th percentile for RPM concentration was 3 2 ng/ml and 10 26 ng/ml,respectively.9 5%(8/84)patients suffered from acute rejection during the 6 month period after transplantation in this study, and the concentration of RPM in these was lower than that in non rejection patients(P=0.001). Hyperlipidemia and liver dysfunction were the most frequently adverse events, and RPM concentration was significantly associated with the concentration of triglyceride. Conclusions 4～8 ng/ml is a suitable level for RPM concentration. Regular drug monitoring and reasonable dose modulation may increase the validity and security of RPM.