1.Predictive value of preoperative CT-based diagnosis of sarcopenia on the prognosis of patients with pancreatic cancer
Chen CHEN ; Ziyao WANG ; Shuseng QIAN
Tumor 2025;45(3):269-275
Objective:Exploring the predictive value of sarcopenia based on preoperative CT diagnosis for the prognosis of patients with pancreatic cancer.Methods:A retrospective analysis was conducted on the clinical,pathological,and imaging data of 488 patients who underwent radical resection for pancreatic cancer,to analyze the correlation between sarcopenia and the prognosis of patients with pancreatic cancer.Results:Among the 488 patients included,281 had sarcopenia before surgery and 207 did not.The COX proportional hazards regression model showed that sarcopenia was an independent risk factor for overall survival in pancreatic cancer patients[hazard ratio 1.43(95%confidence interval:1.02-1.99);P=0.04],while preoperative sarcopenia was not associated with postoperative disease-free survival(P>0.05).Conclusion:Sarcopenia diagnosed based on preoperative CT is significantly correlated with the overall survival of patients with pancreatic cancer after surgery and is an independent risk factor for the overall survival of patients with pancreatic cancer after surgery.
2.Predictive value of preoperative CT-based diagnosis of sarcopenia on the prognosis of patients with pancreatic cancer
Chen CHEN ; Ziyao WANG ; Shuseng QIAN
Tumor 2025;45(3):269-275
Objective:Exploring the predictive value of sarcopenia based on preoperative CT diagnosis for the prognosis of patients with pancreatic cancer.Methods:A retrospective analysis was conducted on the clinical,pathological,and imaging data of 488 patients who underwent radical resection for pancreatic cancer,to analyze the correlation between sarcopenia and the prognosis of patients with pancreatic cancer.Results:Among the 488 patients included,281 had sarcopenia before surgery and 207 did not.The COX proportional hazards regression model showed that sarcopenia was an independent risk factor for overall survival in pancreatic cancer patients[hazard ratio 1.43(95%confidence interval:1.02-1.99);P=0.04],while preoperative sarcopenia was not associated with postoperative disease-free survival(P>0.05).Conclusion:Sarcopenia diagnosed based on preoperative CT is significantly correlated with the overall survival of patients with pancreatic cancer after surgery and is an independent risk factor for the overall survival of patients with pancreatic cancer after surgery.

Result Analysis
Print
Save
E-mail