Pathology images,being an essential part of medical imaging,are critical for early diagnosis of diseases such as cancer.The study introduces edge computing into pathology image research,and presents an edge inference solution for medical pathological image recognition and analysis,aiming to leverage the advantages of edge computing and combine with deep learning methods to achieve real-time pathology image detection.Experimental results show that the solution protects patient privacy well,improves the efficiency and real time of medical image processing,and greatly reduces costs,demonstrating that it has high practical application value and can provide more and efficient accurate support for medical diagnosis and treatment.

Pathology images,being an essential part of medical imaging,are critical for early diagnosis of diseases such as cancer.The study introduces edge computing into pathology image research,and presents an edge inference solution for medical pathological image recognition and analysis,aiming to leverage the advantages of edge computing and combine with deep learning methods to achieve real-time pathology image detection.Experimental results show that the solution protects patient privacy well,improves the efficiency and real time of medical image processing,and greatly reduces costs,demonstrating that it has high practical application value and can provide more and efficient accurate support for medical diagnosis and treatment.

The incidence of chronic fatigue syndrome(CFS)has gradually increased in recent years.Although CFS can severely affect patient quality of life,its clinical diagnosis is easily overlooked.Elucidating the pathogenesis of CFS and treating it from both etiological and symptomatological perspectives are crucial for patient recovery;however,its unclear pathogenesis means that etiological treatment options are limited,and current treatments mainly focus on improving clinical symptoms.In this context,there is a need to establish and evaluate a suitable animal model.This article comprehensively integrates the diagnostic criteria of CFS and progress in related basic research.We also summarize the behavioral experimental method used to evaluate CFS models in basic research in the past 5 years and discuss these evaluations from the perspectives of general condition,fatigue state,cognitive function,emotional state,and pain degree.This review aims to present the current situation,expose problems,trigger reflection,and promote improvements in the behavioral evaluation of animal models of CFS.

The incidence of chronic fatigue syndrome(CFS)has gradually increased in recent years.Although CFS can severely affect patient quality of life,its clinical diagnosis is easily overlooked.Elucidating the pathogenesis of CFS and treating it from both etiological and symptomatological perspectives are crucial for patient recovery;however,its unclear pathogenesis means that etiological treatment options are limited,and current treatments mainly focus on improving clinical symptoms.In this context,there is a need to establish and evaluate a suitable animal model.This article comprehensively integrates the diagnostic criteria of CFS and progress in related basic research.We also summarize the behavioral experimental method used to evaluate CFS models in basic research in the past 5 years and discuss these evaluations from the perspectives of general condition,fatigue state,cognitive function,emotional state,and pain degree.This review aims to present the current situation,expose problems,trigger reflection,and promote improvements in the behavioral evaluation of animal models of CFS.

Objective:To evaluate the role of high-resolution computer tomography (HRCT) with multiplanar reformation (MPR) in the differential diagnosis of renal papillary calcification and renal calculi.Methods:Retrospective study was used upon collecting the clinical data of pilots who were suspected of renal calculi by HRCT and diagnosed by ureteroscopy in the Air Force Medical Center from June of 2017 to October of 2021. MPR was used to analyze and measure the acquired images. According to the results of ureteroscopy, they were divided into renal papillary calcification group and renal calculi group. The sizes (transverse diameter, longitudinal diameter, and difference between transverse and longitudinal diameters) and CT values of the lesions were compared between 2 groups and analyzed.Results:Eighteen pilots were included. A total of 33 lesions were detected, including 8 renal papillary calcification and 25 renal calculi. ①The transverse diameter of renal papillary calcification lesions was (2.93±0.42) mm, the longitudinal diameter was (3.00±0.41) mm, and the difference between transverse and longitudinal diameters was (0.12±0.81) mm; the transverse diameter of renal calculi lesions was (4.47±2.18) mm, the longitudinal diameter was (4.01±1.49) mm, and difference between longitudinal and transverse diameters was (0.89±0.96) mm. The differences between 2 groups were statistically significant ( t=3.78, 2.93, 3.77, P=0.001, 0.007, 0.001). ②The CT values of renal papillary calcification and renal calculi was (270.87±86.95) HU and (610.74±347.03) HU, respectively, with a statistically significant difference ( t=4.32, P<0.001). ③The area under the receiver operating characteristic curve of the transverse diameter, longitudinal diameter and difference between longitudinal and transverse diameters, as well as CT values, was 0.793, 0.701, 0.894, 0.788, respectively; the critical value of the difference between longitudinal and transverse diameters was 0.225 mm, and the Youden′s J statistic was 0.745. Its sensitivity and specificity was 87.0% and 87.5% respectively. Conclusions:HRCT combined with MPR is helpful to differentiate renal papillary calcification from renal calculi. The diagnostic accuracy is the highest on differentiating the difference between the longitudinal and transverse diameter of the lesion.

At present, China has entered a deeply aging society, and preparing for elderly care actively can respond to the aging population. This article reviews the theoretical basis, research status, evaluation tools, and influencing factors of elderly care preparation, aiming to provide reference for deepening the elderly care preparation work and achieving healthy aging.

Traditional Chinese Medicine (TCM) external therapy for sleep disorder of chronic fatigue syndrome (CFS) has good anti-fatigue effect and can improve sleep quality of patients. The treatment for sleep disorders of CFS with TCM external treatment mainly adopts acupuncture, moxibustion, massage, TCM bath, transcutaneous acupoint electrical stimulation and auricular point sticking, etc., or alone, or comprehensive application, or combined with oral Chinese materia medica. The appropriate treatment method can be selected according to the patients' condition and compliance, which reflects the unique advantages of TCM syndrome differentiation and treatment and the treatment according to people and time. The existing research still needs to further form a standardized and recognized diagnosis and treatment system, so as to better guide clinical popularization and application.

Objective:To evaluate the role of high-resolution computer tomography (HRCT) with multiplanar reformation (MPR) in the differential diagnosis of renal papillary calcification and renal calculi.Methods:Retrospective study was used upon collecting the clinical data of pilots who were suspected of renal calculi by HRCT and diagnosed by ureteroscopy in the Air Force Medical Center from June of 2017 to October of 2021. MPR was used to analyze and measure the acquired images. According to the results of ureteroscopy, they were divided into renal papillary calcification group and renal calculi group. The sizes (transverse diameter, longitudinal diameter, and difference between transverse and longitudinal diameters) and CT values of the lesions were compared between 2 groups and analyzed.Results:Eighteen pilots were included. A total of 33 lesions were detected, including 8 renal papillary calcification and 25 renal calculi. ①The transverse diameter of renal papillary calcification lesions was (2.93±0.42) mm, the longitudinal diameter was (3.00±0.41) mm, and the difference between transverse and longitudinal diameters was (0.12±0.81) mm; the transverse diameter of renal calculi lesions was (4.47±2.18) mm, the longitudinal diameter was (4.01±1.49) mm, and difference between longitudinal and transverse diameters was (0.89±0.96) mm. The differences between 2 groups were statistically significant ( t=3.78, 2.93, 3.77, P=0.001, 0.007, 0.001). ②The CT values of renal papillary calcification and renal calculi was (270.87±86.95) HU and (610.74±347.03) HU, respectively, with a statistically significant difference ( t=4.32, P<0.001). ③The area under the receiver operating characteristic curve of the transverse diameter, longitudinal diameter and difference between longitudinal and transverse diameters, as well as CT values, was 0.793, 0.701, 0.894, 0.788, respectively; the critical value of the difference between longitudinal and transverse diameters was 0.225 mm, and the Youden′s J statistic was 0.745. Its sensitivity and specificity was 87.0% and 87.5% respectively. Conclusions:HRCT combined with MPR is helpful to differentiate renal papillary calcification from renal calculi. The diagnostic accuracy is the highest on differentiating the difference between the longitudinal and transverse diameter of the lesion.

Objective: To investigate the clinical effect of percutaneous curved vertebroplasty in the treatment of thoracolum-bar osteoporotic vertebral compression fractures (OVCFs). Methods: All of 85 patients with single thoracolumbar vertebral OVCFs who met the admission criteria from January 2017 to July 2018 were divided into three groups according to the random dig-its table method. They were treated with percutaneous curved vertebroplasty, routine unipedicular PVP and routine bipedicular PVP respectively. There were 25 patients in the percutaneous curved vertebroplasty group, 6 males and 19 females; aged 56-80 years, with an average age of 70.6±9.7 years. Fracture vertebral body distribution: T₁₀ 2 cases, T₁₁ 4 cases, T₁₂ 3 cases, L₁ 9 cases, L₂ 3 cases, L₃ 1 case, L₄ 1 case and L₅ 2 cases. There were 32 patients in the routine unipedicular PVP group, 6 males and 26 fe-males; aged 58-75 years, with an average age of 69.5±9.3 years. Fracture vertebral body distribution: T₁₀ 2 cases, T₁₁ 4 cases, T₁₂ 5 cases, L₁ 11 cases, L₂ 6 cases, L₃ 1 case, L₄ 1 case and L₅ 2 cases. There were 28 patients in the routine bipedicular PVP group, 5 males and 23 females; aged 59-81 years, with an average age of 69.8±8.8 years. Fracture vertebral body distribution: T₁₀ 2 cases, T₁₁ 4 cases, T₁₂ 4 cases, L₁ 10 cases, L₂ 4 cases, L₃ 1 case, L₄ 1 case and L₅ 2 cases. The operation time, injected cement volume, in-traoperative blood loss were recorded and analyzed. Preoperative, postoperative 1 week and 3 months visual analogue scale scores and oswestry disability index were adopted to value the clinical improvements. Preoperative, postoperative 1 week and 3 months relative vertebral height and kyphosis correction, and the cement leakage rate were measured and analyzed. Results: There was no significant difference in the data of gender, age, VAS scores, ODI and distribution of fracture vertebrae among the three groups (P>0.05), and the baseline data was comparable. The average VAS score in the percutaneous curved vertebroplasty group was 2.3±0.5 at 1 week after surgery, that of the routine unipedicular PVP group was 2.4±0.4 and that of the routine bipe-dicular PVP group was 2.4±0.4; the average ODI in the percutaneous curved vertebroplasty group was 19.8%±3.9%, that of the routine unipedicular PVP group was 20.0%±4.1% and that of the routine bipedicular PVP group was 19.9%±3.8%; they were lower than the preoperative data, which were statistically significant (P<0.001). The average relative vertebral height in the percutaneous curved vertebroplasty group was 48.99%±9.23% at 3 months after surgery, that of the routine unipedicular PVP group was 47.11%±10.12% and that of the routine bipedicular PVP group was 46.71%±11.16%; the average kyphosis cor-rection in the percutaneous curved vertebroplasty group was 6.21%±1.94%, that of the routine unipedicular PVP group was 5.22%±2.07% and that of the routine bipedicular PVP group was 5.97%±2.09%; there was 1 cement leakage case in the per-cutaneous curved vertebroplasty group; those of the routine unipedicular PVP group were 4 cases and those of the routine bipe-dicular PVP group were 6 cases; there was no significant difference among the three groups (P>0.05). Operation time 39.10±2.00 min vs 38.70±1.70 min, injected cement volume 3.60±0.11 ml vs 3.50±0.13 ml and blood loss 5.10±0.30 ml vs 5.00±0.40 ml of the percutaneous curved vertebroplasty group and the routine unipedicular PVP group were less than those of the routine bipedicular PVP group, which were statistically significant (P<0.05). Conclution Percutaneous curved vertebroplasty could achieve satisfactory clinical outcomes for OVCFs, with advantages of less operation time, less blood loss, limited X-ray expo-sure, less injected cement volume, and more balanced augmentation for stabilization of the affected vertebrae and total verte-bral column.

Objective To investigate the occurrence of deep venous thrombosis (DVT) in the perioperative period of patients with fracture distal to the knee,so that clinicians have a better understanding of the occurrence of DVT in the perioperative period of the fracture distal to the knee.Methods A retrospective analysis of the clinical data of 365 patients with distal knee fractures who underwent surgery in the Department of Orthopaedics Trauma,Xi'an Jiaotong University Medical College Red Cross Hospital from June 2014 to March 2018 was conducted.There were 213 males and 152 females,aged (45.05 ± 15.24) years,with an age range of 17-83 years.Classification of fracture sites:177 cases of tibiofibular shaft fracture,130 cases of ankle fracture,and 58 cases of foot fracture.According to whether thrombosis occurred or not,the patients were divided into thrombotic group and non-thrombotic group before and after operation.There were 66 patients with thrombosis before operation,299 patients without thrombosis before operation,88 patients with thrombosis after operation,and 277 patients without thrombosis after operation.The incidence of thrombosis and the location of the thrombus were recorded.The sex,age,fracture site,ASA score,operation time,the time from injury to admission,the time from injury to surgery,intraoperative tourniquet time,intraoperative blood transfusion volume,intraoperative blood loss,intraoperative transfusion volume,hemoglobin volume at admission and 1 day after operation,D-dimer level at admission and 1 day after operation,multiple injuries,chronic hepatitis and medical diseases were analyzed.The measuremernt data of normal distribution and homogeneity of variance were expressed as mean ± standard deviation (Mean ± SD),the t test was used for comparison between two groups.The comparison of count data was performed by x2 test or Fisher exact probability method,and multivariate logistic regression analysis was performed on the risk factors affecting the occurrence of DVT in both lower extremities.Results The preoperative DVT rate was 18.1％ (66/365).In patients with thrombosis,distal thrombosis accounted for 93.94％ (62/66),and mixed thrombosis accounted for 6.06％ (4/66).The incidence of postoperative DVT was 24.1％ (88/365).In patients with thrombosis,distal thrombosis accounted for 94.32％ (83/88),proximal thrombosis accounted for 1.14％ (1/88),and mixed thrombus accounted for 4.55％ (4/88).Fracture site,ASA score,operation time,intraoperative tourniquet time,intraoperative blood transfusion volume,intraoperative blood loss,intraoperative transfusion volume were not statistically significant(P ＞0.05).Age ≥ 40 years (OR =2.691,95％ CI:1.422-5.093,P =0.002),the time from injury to admission ＞ 3 days (OR =1.927,95 ％ CI:1.072-3.463,P =0.028)were independent risk factors for DVT formation in fracture distal to the knee before operation.Age ≥ 40 years (OR =3.925,95 ％ CI:2.161-7.129,P =0.000),the time from injury to surgery ＞ 5 days (OR =1.835,95 ％ CI:1.080-3.119,P =0.025),D-dimer level at 1 day after operation (OR =1.191,95％ CI:1.096-1.293,P =0.000),combined with multiple injuries (OR =1.981,95％ CI:1.006-3.902,P =0.048),combined with coronary atherosclerotic heart disease (OR =2.692,95％ CI:1.112-6.517,P =0.028) were independent risk factor for DVT formation after operation for fracture distal to the knee.Conclusions The occurrence of DVT before and after the fracture of the knee is mainly caused by distal thrombosis,and proximal thrombosis also occurs.Those patients aged≥40 years,combined with multiple injuries and coronary heart disease,should focus on preventing the occurrence of DVT.After the injury,the patient is immediately admitted to the hospital for DVT screening,and when the general condition allowed,shortening the preoperative waiting time can reduce the occurrence of DVT.