1.The NO-sGC-cGMP pathway and heart failure
Dilu LI ; Yuanyuan PEI ; Wuchao WANG ; Lingjie CAO ; Fengtao YANG ; Shuangkui SHI ; Guyue ZHOU ; Kunyu YANG ; Jihong ZHU
Chinese Journal of Clinical Pharmacology and Therapeutics 2025;30(5):702-708
Heart failure,as a global public health challenge,is experiencing an increasingly severe disease burden.Given the close relationship be-tween the Nitric Oxide-Soluble Guanylate Cyclase-Cyclic Guanosine Monophosphate(NO-sGC-cGMP)signaling pathway and heart failure,this study,through a comprehensive search and review of re-cent literature on the NO-sGC-cGMP pathway and heart failure,aims to outline the mechanism of ac-tion of this signaling pathway and its connection with heart failure,in order to explore new avenues for the treatment of heart failure.
2.The NO-sGC-cGMP pathway and heart failure
Dilu LI ; Yuanyuan PEI ; Wuchao WANG ; Lingjie CAO ; Fengtao YANG ; Shuangkui SHI ; Guyue ZHOU ; Kunyu YANG ; Jihong ZHU
Chinese Journal of Clinical Pharmacology and Therapeutics 2025;30(5):702-708
Heart failure,as a global public health challenge,is experiencing an increasingly severe disease burden.Given the close relationship be-tween the Nitric Oxide-Soluble Guanylate Cyclase-Cyclic Guanosine Monophosphate(NO-sGC-cGMP)signaling pathway and heart failure,this study,through a comprehensive search and review of re-cent literature on the NO-sGC-cGMP pathway and heart failure,aims to outline the mechanism of ac-tion of this signaling pathway and its connection with heart failure,in order to explore new avenues for the treatment of heart failure.
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