Objective To evaluate the compatibility of commonly used intravenous drugs in the ICU of Hebei General Hospital and to propose optimization strategies.Methods Data from 35 intravenous drugs used in ICU from January 1 to December 31,2023 were analyzed using the Micromedex database and relevant literature.Results A compatibility chart for 35 drugs was created.Total 595 combinations,of which 279(46.9％)were compatible,22(3.7％)were incompatible,28(4.7％)were uncertain,and 266(44.7％)were unknown.Conclusion Drug co-administration is common in the ICU,but there is a lack of safety evidence and guidelines.There is an urgent to improve compatibility data and develop comprehensive resources to ensure safer intravenous drug administration.

Objective To evaluate the compatibility of commonly used intravenous drugs in the ICU of Hebei General Hospital and to propose optimization strategies.Methods Data from 35 intravenous drugs used in ICU from January 1 to December 31,2023 were analyzed using the Micromedex database and relevant literature.Results A compatibility chart for 35 drugs was created.Total 595 combinations,of which 279(46.9％)were compatible,22(3.7％)were incompatible,28(4.7％)were uncertain,and 266(44.7％)were unknown.Conclusion Drug co-administration is common in the ICU,but there is a lack of safety evidence and guidelines.There is an urgent to improve compatibility data and develop comprehensive resources to ensure safer intravenous drug administration.