1.Neoadjuvant sintilimab and apatinib combined with perioperative FLOT chemotherapy for locally advanced gastric cancer: A prospective, single-arm, phase II study.
Huinian ZHOU ; Bo LONG ; Zeyuan YU ; Junmin ZHU ; Hanteng YANG ; Changjiang LUO ; Wenjuan ZHANG ; Chi DONG ; Xiaoying GUAN ; Long LI ; Gengyuan ZHANG ; Hongtai CAO ; Shigong CHEN ; Linyan ZHOU ; Qichen HE ; Shiying GAN ; Xiangyan JIANG ; Qianlin GU ; Keshen WANG ; Wengui SHI ; Long QIN ; Zuoyi JIAO
Chinese Medical Journal 2024;137(21):2615-2617
2.Investigation on medical practice of overseas acupuncturists based on the top 5 general hospitals in the United States of America and the inspiration
Shuaishuai LIU ; Shiying HUANG ; Lu GAN ; Yang LUO ; Leyao XIAN ; Luwen ZHANG
International Journal of Traditional Chinese Medicine 2023;45(6):667-672
This study selected the top five general hospitals in the United States of America, collected the practice information of acupuncturists through the official website, and analyzed the professional department, expertise, professional title, education background, residency, fellowship, board certification, etc. of these acupuncturists to understand the practice situation of acupuncturists in the hospitals. The results of the study showed the practice of acupuncturists in the United States of America is improving. With further localization, locally trained acupuncturists have gradually become the main body of acupuncturists; acupuncture treatment is still mainly for analgesia, but the scope of treatment continues to expand, and departments that accept acupuncturists are gradually increasing. However, the group of licensed acupuncturists is still a minority in the group of acupuncturists in the United States of America. Native American physicians still use acupuncture as an alternative option and neglect to obtain a license. The entry barrier for acupuncturists still needs to be raised.
3.Relationship between abuse experience with suicidal ideation and behavior of junior middle school students in Chongqing
WEI Min, TANG Yonglong, LI Shiying, FU Mingcheng, GAN Nina, XIE Fanglu, LUO Ya
Chinese Journal of School Health 2021;42(11):1679-1682
Objective:
To explore the relationship between abuse experience with suicidal ideation and suicide attempts of junior middle school students, and to provide a reference for suicide prevention of junior middle school students.
Methods:
Cluster sampling method were used to selct 10 289 junior middle school students from 25 districts and counties of Chongqing were included in the analysis of this study from July to September in 2020. And Questionnaire on Abuse in Childhood and Mental Health Scale for Middle School Students were applied to collect the data about demographic information, suicide ideation and behavior.
Results:
The prevalence of suicidal ideation and suicide attempts among junior middle school students were 20.93% and 10.83%, respectively. Multivariate Logistic regression model found that after controlling for demographic variables and mental health, emotional abuse ( OR =2.07) and emotional neglect ( OR =2.03) showed higher correlations with suicidal ideation than the other three types of childhood abuse( OR physical neglect =1.19, OR physical abuse =1.60, OR sexual abuse =1.37, P <0.05); and sexual abuse ( OR =2.29) and physical neglect ( OR =1.87) showed higher associations with suicide attempt than the other three types of abuse( OR emotional abuse =1.63, OR emotional neglect =1.59, OR physical abuse =1.50, P <0.01).
Conclusion
All five types of child abuse were independent risk factors for suicidal ideation and suicide attempts, and emotional neglect and emotional abuse had a greater effect on suicidal ideation, sexual abuse and physical neglect had a greater effect on suicide attempts.
4. Correlation analysis between Dx-pH monitoring and proton pump inhibitor test in the diagnosis of laryngopharyngeal reflux disease
Zhiling CHEN ; Huawei WU ; Xianwei MEI ; Wenhua YIN ; Shiying XU ; Suqin LIU ; Yanchun CHEN ; Gan WANG ; Chenjia ZHANG ; Xiaolong DING ; Jiani WU
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2020;55(1):34-39
Objective:
The consistency of 24-hour oropharyngeal Dx-pH monitoring and proton pump inhibitor(PPI) test in the diagnosis of laryngopharyngeal reflux disease (LPRD) was investigated.
Methods:
Sixty patients with laryngopharyngeal reflux (LPR) related symptoms who had never received PPI treatment were assessed by reflux symptom index (RSI) and reflux finding score (RFS) between October 2017 and October 2018, including 28 males and 38 females, aged from 16 to 72 years, with a medium age of 38 years. Prior to treatment, all patients were evaluated with 24 hours oropharyngeal Dx-pH monitoring(Restech). After empiric therapy with PPI twice-daily for 8 weeks, the efficacy was evaluated according to posttreatment RSI score.The data was analysed with Kruskal-Wallis test, Student Newman Keuls test and consistency check.
Results:
(1)Among all 60 patients,13 patients (21.7%) had pathologic Ryan score and all resulted responsive to PPI;27 patients (45.0%) with a negative Ryan score were unresponsive to PPI; 20 patients (33.3%) despite a negative Ryan score resulted responsive to PPI therapy. Considering responsiveness to PPI therapy as the gold standard for the diagnosis of LPRD, the sensitivity, specificity, positive predictive value and negative predictive value of Ryan score were 39.4%, 100%, 100% and 57.4% respectively. The Kappa value was 0.369 (


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