Objective To understand the change trend and characteristics of nosocomial infection through the comprehensive surveillance on nosocomial infection in infectious diseases specialized hospitals dur-ing 2017-2023 to provide an evidence for the prevention,control and management of nosocomial infection.Methods The surveillance indicators of nosocomial infection in a hospital during 2017-2023 were collected.The nosocomial infection rate,nosocomial infection rate in different inpatient wards,nosocomial infection sites,nosocomial infection pathogenic bacterial distribution and susceptibility factors conducted the statistical analysis.Results A total of 93 254 patients were admitted and treated during 2017-2023.The nosocomial in-fection rate and infection case-times rate showed the decreasing trend(P＜0.05).The case-times rate of the patients in the AIDS wards was 3.75％,which was higher than 0.79％in the tuberculosis wards(P＜0.05).The nosocomial infection case-times rate in the two wards areas during 2017-2023 showed the decreasing trend(P＜0.05).The infection sites were mainly the respiratory system(61.56％),blood system(9.44％)and urinary system(8.61％).A total of 803 strains of pathogenic bacteria were detected out,which were mainly Gram negative bacteria(63.89％),the top five were in turn Klebsiella pneumoniae(16.19％),Esche-richia coli(15.57％),Acinetobacter baumannii(10.83％),Pseudomonas aeruginosa(8.84％)and Staphylo-coccus aureus(7.22％).The top three of susceptibility factors were low immune function(58.78％),long term antibiotic use(11.29％)and ventilator use(9.20％).Conclusion Initiatively carrying the hospital infec-tion surveillance could accurately grasp the incidence trends and provide the direction and data support for pre-vention and control priorities.

Objective:To develop an age-appropriate and disease-specific social adaptation measurement tool for adolescents infected with HIV in the context of Chinese culture, and to test its reliability and validity.Methods:Through literature review and consultation with 8 experts, this study constructed the conceptual framework of social adaptation of adolescents infected with HIV and formulated the dimensions and items of the scale. The convenient sampling method was adopted, and questionnaires were distributed online and offline at Beijing Ditan Hospital, Xuzhou Center for Disease Control and Prevention and Yunnan Provincial Infectious Disease Hospital from October 2020 to February 2021 for questionnaire validity testing. A preliminary age-specific and disease-adaptable Social Adaptation Scale for HIV Infected Adolescents was prepared using methods such as project analysis and reliability and validity testing.Results:The scale consisted of 3 dimensions of cognition, emotion and will, 5 variables, and a total of 23 items. The Cronbach's α coefficient of the scale was 0.856, and the split reliability was 0.836. The item-level content validity index ( I- CVI) of the scale was 0.750-1.000, the scale-level content validity index ( S- CVI) was 0.940, and the scale score and subjective well-being scale score were positivelycorrelated ( P<0.05) . Factor analysis extracted 5 common factors, and the cumulative explanatory variable was 61.156%. Conclusions:The scale has good reliability, validity and feasibility, which can be used as an evaluation tool for social adjustment of HIV-infected adolescents in China.