Objective To study the change law of immunoglobulin (Ig) (IgG,IgA,IgM) and complement levels (C3,C4) in the peripheral blood of pilots by quantitative detection and to suggest the preventive measures.Methods IMMAGE800 instrument was used to detect the immunoglobulin and complement levels in 383 active pilots and 100 ground crews.Pilots were divided into bomber,transporter,helicopter and fighter groups by aircraft type.The ground crews were chosen as control group.Results Comparing to the control group,pilots showed lower peripheral blood IgG and IgM but higher C3 and C4 levels.Bomber group had lower IgG and higher C3 and C4 levels (P＜0.05).Transporter group had lower IgG and IgM but higher C3 and C4 levels (P＜0.05).Helicopter group showed lower IgG and IgM but higher C4 level (P＜0.05).Fighter group showed lower IgG but higher C3 and C4 levels (P＜0.05).Conclusions The changes on immunoglobulin and complement levels indicate the certain harmful effects on pilot's immune system.The environment factors may be the main reason led to pilot's lower IgG and IgM but higher C3 and C4 levels.The prevention of electromagnetic radiation in flight should be strengthened as the basic measures for maintaining pilot's immune functions.

Objective To study the change law of immunoglobulin (Ig) (IgG,IgA,IgM) and complement levels (C3,C4) in the peripheral blood of pilots by quantitative detection and to suggest the preventive measures.Methods IMMAGE800 instrument was used to detect the immunoglobulin and complement levels in 383 active pilots and 100 ground crews.Pilots were divided into bomber,transporter,helicopter and fighter groups by aircraft type.The ground crews were chosen as control group.Results Comparing to the control group,pilots showed lower peripheral blood IgG and IgM but higher C3 and C4 levels.Bomber group had lower IgG and higher C3 and C4 levels (P＜0.05).Transporter group had lower IgG and IgM but higher C3 and C4 levels (P＜0.05).Helicopter group showed lower IgG and IgM but higher C4 level (P＜0.05).Fighter group showed lower IgG but higher C3 and C4 levels (P＜0.05).Conclusions The changes on immunoglobulin and complement levels indicate the certain harmful effects on pilot's immune system.The environment factors may be the main reason led to pilot's lower IgG and IgM but higher C3 and C4 levels.The prevention of electromagnetic radiation in flight should be strengthened as the basic measures for maintaining pilot's immune functions.