Objective:To explore the relationship between acute leukemia and blood lipid level.Methods:The Chinese and English literature on the relationship between acute leukemia and blood lipid level published in PubMed, Web of Science, Cochrane library, CNKI, Wanfang, and VIP databases from the establishment of the database to December 2023 was searched, the literature that met the evaluation criteria was screened, and the quality of the literature was evaluated by using the Newcastle-Ottawa scale. Basic clinical characteristics and blood lipid-related data were obtained from the acute leukemia patients (acute leukemia group) and the healthy individuals who underwent physical examination or patients with non-hematological disorders that did not lead to abnormal blood lipid metabolism and who did not take medications that affected blood lipid during the same period (control group). Meta-analysis of the differences in peripheral blood levels of total cholesterol (TC), triacylglycerol (TG), low-density lipoprotein cholesterol (LDL-c), and high-density lipoprotein cholesterol (HDL-c) between the two groups was carried out by using Stata 14.0 software to make forest plots and to calculate the combined weighted mean difference (WMD) or standardised mean difference (SMD) and 95% CI. Results:Six articles were finally included, published between 2005 and 2023, all of which were of moderate quality. Finally, 558 patients with acute leukemia and 323 controls were included in the analysis. By Meta-analysis, TG level in the acute leukemia group was higher than that in the control group (WMD = 0.30, 95% CI: 0.07-0.54, P = 0.012), HDL-c (SMD = -1.54, 95% CI: -2.11--0.97, P < 0.001) and LDL-c (WMD = -0.57, 95% CI: -0.72 - -0.41, P < 0.001) levels were lower than those in the control group, and the differences were all statistically significant; the difference in TC between the acute leukemia group and the control group was not statistically significant (WMD = -0.34, 95% CI: -0.82-0.13, P = 0.157). Conclusions:Compared with normal subjects, patients with acute leukemia have high TG level and low LDL-c and HDL-c levels.

Objective:To explore the effect of group psychological counseling on the improvement of negative emotion and vision-related quality of life in patients with primary glaucoma during the perioperative period.Methods:A total of 96 patients who underwent primary glaucoma surgery in Ophthalmology Ward of Beijing Tongren Hospital were selected from June 2018 to December 2019 and they were divided into the intervention group ( n=48) and the control group ( n=48) by the random number table method. The control group was given routine care during the perioperative period of glaucoma, while the intervention group was given group psychological counseling on the basis of the control group. Self-Rating Anxiety Scale (SAS) , Self-Rating Depression Scale (SDS) and self-made Vision-related Quality of Life Questionnaire were used to evaluate the patients. Results:The SAS score of the intervention group and the control group before intervention was respectively (56.79±1.86) and (56.77±1.92) , and the difference was not statistically significant ( P>0.05) . After the intervention, SAS score of the intervention group and the control group was respectively (41.31±3.37) and (47.45±2.05) , and the difference was statistically significant ( P<0.01) . The SDS score of the intervention group and the control group before intervention was respectively (66.97±3.27) and (66.64±2.43) , and the difference was not statistically significant ( P>0.05) . After the intervention, SDS score of the intervention group and the control group was respectively (44.91±2.04) and (52.52±1.86) , and the difference was statistically significant ( P<0.01) . The sleep quality and self-care ability in the intervention group were better than those in the control group, and the differences were statistically significant ( P<0.05) . Conclusions:Group psychological counseling can help to reduce negative emotions of patients, improve their sleep quality and self-care ability and improve their quality of life.

Objective? To explore the mental state of laryngeal carcinoma patients after total laryngectomy and to analyze its correlations with coping style and social support. Methods? From January 2017 to October 2017, we selected 36 laryngeal carcinoma patients with total laryngectomy in otolaryngology dead and neck surgery at Beijing Tongren Hospital, Capital Medical University as subjects by convenience sampling. All of the patients were investigated with the Self-rating Depression Scale (SDS), Self-rating Anxiety Scale (SAS), Medical Coping Modes Questionnaire (MCMQ) and Social Support Rating Scale (SSRS). A total of 36 questionnaires were sent out and 34 of them were collected. Results? Among 34 patients, the total scores of SAS and SDS were (45.38±10.27) and (50.32±11.82) respectively. The score of "avoidance" coping style of patients after total laryngectomy was higher than that of norm with a statistical difference (P＜ 0.05). Pearson correlation analysis showed that SAS and SDS were negatively correlated with the total score of social support (P＜0.05);SAS and SDS were positively correlated with the confrontation dimension of coping style (P＜0.05), and were negatively correlated with the avoidance dimension (P＜ 0.05). Conclusions? After total laryngectomy, patients are with high levela of anxiety and depression. Medical staff should guide patients to take correct coping styles after surgery to face diseases, and improve patients' social support to relieve patients' negative emotions and total laryngectomy,and to promote the rehabilitation of diseases.

Objective To explore the detection rate and clinical characteristics of multiple somatic symptoms among adult outpatients in cardiology,neurology and GI clinics.Methods The general demographic data and disease-related information of 1 497 patients in Beijing Chaoyang Hospital,Beijing Anzhen Hospital and Beijing Tongren Hospital were collected through continuous inquiry and screening.Physical symptoms and depressive symptoms were assessed by Patient Health Questionnaire-15 (PHQ-15) and Patient Health Questionnaire-9 (PHQ-9).The patients were divided into multiple somatic symptoms group (SOM+group,PHQ-15≥10) and non-multiple somatic symptoms group (SOM-group,PHQ-15＜10).The detection rate of multiple somatic symptoms was calculated.Partial correlation analysis was used to analyze the correlation of PHQ-15 with the demographic,course of disease,cumulative number of visits,and the total score of PHQ-9.Results The overall detection rate of multiple somatic symptoms was 32.67％ (489/1 497)in the three hospitals,and the highest was found in the department of digestive medicine (37.74％,191/506).There were significant differences in gender (x2=36.85,P＜0.01),working status (x2=19.78,P＜0.01),visiting department (x2=9.64,P＜0.01),first visiting/repeated visiting (x2=6.67,P＜0.01),and the total score of PHQ-9 (x2=231.52,P＜0.01).The detection rate of female patients was higher than that of male patients.The detection rates of retired patients and patients who had no daily stable work were higher than patients who had daily stable work.The detection rate of re-visited patients was higher than that of first-visited patients.The illness duration (r=0.07,P＜0.05,Bonferroni correction) and the total score of PHQ-9 (r=0.66,P＜0.05,Bonferroni correction) were positively correlated with the severity of somatic symptoms measured by PHQ-15.Conclusions The detection rate of multiple somatic symptoms was high in general hospitals,especially highest in digestive outpatient clinics,and significantly higher in female,retired,unemployed,re-visited and patients who have depressive symptoms.Depressive symptoms and the illness duration were positively correlated with the severity of somatic symptoms.

Objective To explore the detection rate and clinical characteristics of multiple somatic symptoms among adult outpatients in cardiology,neurology and GI clinics.Methods The general demographic data and disease-related information of 1 497 patients in Beijing Chaoyang Hospital,Beijing Anzhen Hospital and Beijing Tongren Hospital were collected through continuous inquiry and screening.Physical symptoms and depressive symptoms were assessed by Patient Health Questionnaire-15 (PHQ-15) and Patient Health Questionnaire-9 (PHQ-9).The patients were divided into multiple somatic symptoms group (SOM+group,PHQ-15≥10) and non-multiple somatic symptoms group (SOM-group,PHQ-15＜10).The detection rate of multiple somatic symptoms was calculated.Partial correlation analysis was used to analyze the correlation of PHQ-15 with the demographic,course of disease,cumulative number of visits,and the total score of PHQ-9.Results The overall detection rate of multiple somatic symptoms was 32.67％ (489/1 497)in the three hospitals,and the highest was found in the department of digestive medicine (37.74％,191/506).There were significant differences in gender (x2=36.85,P＜0.01),working status (x2=19.78,P＜0.01),visiting department (x2=9.64,P＜0.01),first visiting/repeated visiting (x2=6.67,P＜0.01),and the total score of PHQ-9 (x2=231.52,P＜0.01).The detection rate of female patients was higher than that of male patients.The detection rates of retired patients and patients who had no daily stable work were higher than patients who had daily stable work.The detection rate of re-visited patients was higher than that of first-visited patients.The illness duration (r=0.07,P＜0.05,Bonferroni correction) and the total score of PHQ-9 (r=0.66,P＜0.05,Bonferroni correction) were positively correlated with the severity of somatic symptoms measured by PHQ-15.Conclusions The detection rate of multiple somatic symptoms was high in general hospitals,especially highest in digestive outpatient clinics,and significantly higher in female,retired,unemployed,re-visited and patients who have depressive symptoms.Depressive symptoms and the illness duration were positively correlated with the severity of somatic symptoms.