OBJECTIVE： To investigate and analyze the current status and existing problems of Chinese patent medicine instructions in outpatient department of our hospital， and to provide suggestions for the improvement of Chinese patent medicine instructions. METHODS： A total of 435 copies of Chinese patent medicines instructions using in the outpatient pharmacy of our hospital were collected in 2018. The labeling of usage and dosage of the instructions and other items were not clear and missing items were analyzed statistically. RESULTS： In 435 copies of drug instructions， unclear usage and dosage included usage and dosage were marked only in grams or milliliters （54 kinds， 12.4％）； daily dosage was not clear （165 kinds， 37.9％）； the words “or follow the doctor’s advice” were involved in drug instructions （86 kinds， 19.8％）； the labeling of usage and dosage for special population were not clear （34 kinds， 7.8％）； medication time was not labeled （365 kinds， 83.9％）. Unclear labeling of other items included unclear drug interaction （121 kinds， 27.8％）， unclear matters needing attention （12 kinds， 2.8％）， unclear ADR （307 kinds， 70.6％）， unclear contraindications （257 kinds， 59.1％） and unclear indications （1 kind， 0.2％）. The missing items included that drug dosage for special population （41 kinds， 94.5％）， pharmacological and toxicological items （305 kinds， 70.1％）， clinical trial data （395 kinds， 90.8％）， storage temperature label （377 kinds， 86.7％）. CONCLUSIONS： Missing items and unclear information on safe medication are common in Chinese patent medicine instructions， which need to be standardized and perfected in order to provide reference for rational drug use and guarantee the safety of drug use in patients.

Objective To evaluate clinical significance of platelet/lymphocyte ratio ( PLR) in the differentiation and severity determination of ulcerative colitis .Methods One hundred and ninety-two patients who sought medical care from June 2009 to June 2016, in Changhai Hospital , were enrolled as study subjects , of whom 97 were patients with ulcerative colitis and 95 were patients with irritable bowel syndrome .Differences in PLR between the 2 groups were analyzed and the sensitivity and specificity of PLR in the diag-nosis of ulcerative colitis were also evaluated .Through the modified Mayo score system , the activity of ulcerative colitis was evaluated , and pathological spreading site was determined by colonoscopy , and the correlation between PLR and disease activity and pathological spreading site was evaluated .Results As compared with those of the control group with irritable bowel syndrome , the while blood cell counts, blood platelet counts , PLR, the erythrocyte sedimentation rate and the C-reaction protein of the patients with ulcerative colitis were significantly increased, and statistical significance could be noted when comparisons were made between them (P<0.05).Statis-tical significance could be found in PLR differences between the ulcerative colitis patients and irritable bowel syndrome patients .ROC a-nalysis indicated that sensitivity and specificity of the PLR biomarker were respectively 67%and 58%.PLR data for the patients with irritable bowel syndrome and those with light , moderate and severe ulcerative colitis were 123.73 ±60.47, 114.32 ±43.66, 160.19 ± 56.52 and 253.35 ±86.82 respectively.Results indicated that there was no statistical significance in the clinical data between irritable bowel syndrome and light ulcerative colitis (P=0.54).However, statistical significance could be noted in the data between irritable bowel syndrome and moderate/severe ulcerative colitis(P<0.05).Statistical significance could all be seen in the differences of the clinical data between light, moderate and severe ulcerative colitis (P<0.05).But there was no statistical difference in PLR between different pathological lesions in the patients with ulcerative colitis (P>0.05).Conclusion PLR has certain clinical value and signifi-cance in the identification and diagnosis of ulcerative colitis and irritable bowel syndrome , and at the same time , it could evaluate the degree of inflammation of ulcerative colitis .