1.Research Progress of Glioma in China in 2024
Xiaoman KANG ; Junlin LI ; Wenlin CHEN ; Shanmu JIN ; Yilin LI ; Jiahui LIU ; Yulu GE ; Wenbo WU ; Jiaheng LI ; Yiming LIAN ; Yu WANG ; Wenbin MA
Medical Journal of Peking Union Medical College Hospital 2025;16(6):1437-1448
Glioma is the most common primary malignant tumor of the central nervous system in adults. Despite the standard treatment of surgery combined with radiotherapy and chemotherapy, the prognosis for high-grade glioma patients remains poor, highlighting the urgent need to further explore its pathogenesis and develop new therapeutic strategies. This article reviews the research progress in the field of glioma in China in 2024, covering tumorigenesis mechanisms, tumor immune microenvironment composition, advances in imaging techniques and novel imaging agents, improvements in surgical approaches, mechanisms of radio- and chemoresistance, and explorations of new therapeutic modalities. These studies provide a solid theoretical foundation for advancing clinical diagnosis and treatment of gliomas and may offer new opportunities to improve patient outcomes.
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